Results 191 to 200 of about 310,367 (307)

Targeting toll-like receptors: unveiling potential therapeutic strategies for deep vein thrombosis. [PDF]

Front Immunol
Shao W, Wang Z, Wu J, Guo T, Mo J.
europepmc   +1 more source

Toll-like receptors

, 2000
Marta Muzio, Alberto Mantovani
openalex   +1 more source

Toll-like Receptors as Sensors of Pathogens [PDF]

, 2001
Mikko Hallman, Mika Rämet, R. Alan B. Ezekowitz   +2 more
openalex   +1 more source

A Blast‐Resistant NLR Gene Confers Drought Resistance by Competitively Interacting with an E3 Ligase to Protect Phenylalanine Ammonia‐Lyase in Rice

Advanced Science, EarlyView.
The NLR protein PibH8 interacts with phenylalanine ammonia‐lyase OsPAL1 and E3 ubiquitin ligase OsFBK16. Through competitive binding, PibH8 weakens the interaction between OsFBK16 and OsPAL1, thereby reducing the degradation of OsPAL1 by OsFBK16. The Hap1 allele of PibH8 exhibits a higher expression level than Hap2, thus accumulating more PibH8 protein,
Denghao Xiang, Haifu Tu, Yang Yuan, Yilong Yao, Wanwen Liao, Huaijun Wang, Yu Yan, Yao Wang, Yu Chen, Di Liu, Qingya Lv, Haidong He, Honghong Hu, Xuelei Lai, Meng Yuan, Haiyan Xiong, Faming Dong, Lizhong Xiong   +17 more
wiley   +1 more source

The role of microbiota and toll-like receptors in polycystic ovary syndrome: regulatory mechanisms of androgen metabolism. [PDF]

Endocr Connect
Huang X, Wu L, Zhang Y, Lai X, Sun D.
europepmc   +1 more source

Different Toll-like receptor agonists induce distinct macrophage responses [PDF]

, 2001
Bryan W. Jones, Terry K. Means, Kurt A. Heldwein, Marc A. Keen, Preston J. Hill, John T. Belisle, Matthew J. Fenton   +6 more
openalex   +1 more source

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

Advanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu, Jingchun Shi, Heung‐Lam Mok, Cheng Lyu, Junbang Chen, Chunhua Huang, Hongyan Qin, Chengyuan Lin, Hor‐Yue Tan, Zhaoxiang Bian   +9 more
wiley   +1 more source

RNA Viruses, Toll-Like Receptors, and Cytokines: The Perfect Storm? [PDF]

J Innate Immun
Stegeman SK, Kourko O, Amsden H, Pellizzari Delano IE, Mamatis JE, Roth M, Colpitts CC, Gee K.   +7 more
europepmc   +1 more source

A Novel Polymorphism in the Toll-Like Receptor 2 Gene and Its Potential Association with Staphylococcal Infection

, 2000
Eva Lorenz, Jean Paul Mira, Kristyn L. Cornish, Nancy C. Arbour, David A. Schwartz   +4 more
openalex   +1 more source

Adiponectin Assists Thrombopoietic Agents in ITP Treatment by Enhancing Myosin‐9/Rab6A‐Mediated Trafficking of c‐Mpl in MKs

Advanced Science, EarlyView.
This study revealed that adiponectin facilitates the therapeutic efficiency of thrombopoietic agents by stimulating the membrane trafficking of c‐Mpl in MKs, which provides a point for ITP therapy. Moreover, a novel c‐Mpl trafficking mechanism based on the Myosin‐9/Rab6A complex is constructed. These findings provide new insights into the applicability
Xin Zhao, Huixian Ma, Guosheng Li, Jilong Xiao, Zhiyu Shi, Mingying Li, Xinguang Liu, Tao Sun, Chunyan Ji   +8 more
wiley   +1 more source