A central role for Toll-like 4 receptors in interstitial cystitis? [PDF]
, 2018 Chess-Williams, Russ +2 more
core +1 more source
AGE-LDL Activates Toll Like Receptor 4 Pathway and Promotes Inflammatory Cytokines Production in Renal Tubular Epithelial Cells [PDF]
, 2013 Ao Cheng +5 more
openalex +1 more source
Advanced Science, EarlyView.A solid self‐emulsifying (SSE) platform is loaded with peptide antigens and CpG to form the SSE vaccine. An ApoE‐enriched corona promotes dendritic cell internalization, enabling antigen presentation and T cell activation. Squalene from the SSE also sensitizes T cells by promoting lipid raft formation.
Xueying Shen +8 more
wiley +1 more source
Discovery of substituted 4-aminoquinazolines as selective Toll-like receptor 4 ligands
, 2014 Afshin Nour +13 more
openalex +1 more source
Platelet Ca2+ responses coupled to glycoprotein VI and Toll-like receptors persist in the presence of endothelial-derived inhibitors: roles for secondary activation of P2X1 receptors and release from intracellular Ca2+ stores [PDF]
, 2012 Candice Fung +5 more
openalex +1 more source
A Microbiota‐ and IL‐15‐Dependent Innate‐Like B Cell Progenitor Expressing E4BP4
Advanced Science, EarlyView.This work identifies CD3.NKp46.CD19.NK1.1. NK‐B cells enriched in PDK1‐deficient yet present in wild‐type bone marrow. IL‐15 (via CD122) and TLR9‐microbiota signaling maintain their E4BP4 expression. These cells demonstrate innate immunity, preferentially differentiate into B cells, and unveil a novel microbiota‐ and IL‐15‐dependent regulatory pathway ...
Junming He +11 more
wiley +1 more source
Advanced Science, EarlyView.Polymeric carriers provide versatile platforms for nucleic acid delivery. This review introduces a novel perspective inspired by protein structural organization to explore structure–function relationships of polymeric carriers, highlighting requirements of different nucleic acid payloads.
Hanieh Moradian +3 more
wiley +1 more source
CpG-oligodeoxynucleotides developed for grouper toll-like receptor (TLR) 21s effectively activate mouse and human TLR9s mediated immune responses [PDF]
, 2017 Da‐Wei Yeh +9 more
openalex +1 more source
Toll-like receptors and diseases [PDF]
International Immunopharmacology, 2011 Pablo, Iribarren, Ji Ming, Wang
openaire +2 more sources
Dual Disruption of the Immune Cytokine Spätzle Facilitates Fungal Infection of Diverse Insect Hosts
Advanced Science, EarlyView.The Toll pathway is essential for insect defense against fungal pathogens. This works reports that fungal parasites employ two divergent virulent effectors to target the Toll receptor ligand Spätzle: a metalloprotease degrading it and a hairpin‐like effector hijacking it to block signal transduction. This dual strategy enables the fungus to kill a wide
Shuangxiu Song +7 more
wiley +1 more source