Results 61 to 70 of about 66,338 (163)

Consistency and clarity of pharmacogenomic guidance in UK medicine patient information leaflets: A cross‐sectional analysis

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1934-1939, June 2026.
Pharmacogenomic (PGx) information has the potential to support the safe and effective use of medicines, yet there is uncertainty about how this information can be best communicated to patients. Summaries of product characteristics (SmPCs) and patient information leaflets (PILs) for all UK‐approved medicines with strong evidence supporting a PGx ...
Parth Narlawar, Chloe Ratcliffe, Videha Sharma, William G. Newman, Munir Pirmohamed, John McDermott   +5 more
wiley   +1 more source

HIF inhibition: Current strategies and clinical challenges. [PDF]

Redox Biol
Więch-Walów A, Bartoszewska S, Barton A, Czechowicz P, Dudzik J, Wielockx B, Collawn JF, Bartoszewski R.   +7 more
europepmc   +1 more source

Treatment Advances in Gynecologic Cancers: Insights From Recent Clinical Trials

Cancer Innovation, Volume 5, Issue 3, June 2026.
Overview of immunotherapy and antibody‐drug conjugates, and their mechanism against cancer. (The Graphical Abstract Image was created with BioRender.) ABSTRACT Gynecologic cancers remain a major global health burden for women. Their management has evolved toward a gynecologic oncologist‐led multimodal paradigm.
Yiyang Shen, Xiaofei Jiao, Yuanjia Wen, Zikun Peng, Xuejiao Zhao, Jiahao Liu, Qinglei Gao   +6 more
wiley   +1 more source

Topoisomerase inhibitors in cervical cancer: mechanistic insights and therapeutic strategies. [PDF]

Mol Med
Reddy Y, Pai P, Das I, Nayak S, D'Souza NV, Shetty MG, Sundara BK.   +6 more
europepmc   +1 more source

Surgical Resection of Metastatic Male Breast Cancer to the Brain: An Illustrative Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Preop MRI brain w/ and w/o contrast ‐ T1 post‐contrast coronal view demonstrating a heterogeneously‐enhancing left parietal lobe lesion with surrounding vasogenic edema. ABSTRACT Male breast cancer is rare, accounting for less than 1% of all breast cancers, and central nervous system (CNS) metastases are an uncommon but poor prognostic manifestation ...
Faozia Pio, Max S. Fleisher, Malik Obeidallah, Meagan Mitchell, Lekhaj Daggubati   +4 more
wiley   +1 more source

Design, synthesis, and antibacterial assessment of a new series of ciprofloxacin-based compounds as possible dual DNA gyrase/topoisomerase IV inhibitors. [PDF]

Sci Rep
Al-Wahaibi LH, Alzahrani HA, Bräse S, Youssif BGM, Hisham M.   +4 more
europepmc   +1 more source

Rezatapopt and the Return of Targetable p53

MedComm, Volume 7, Issue 7, July 2026.
Yuanze Luo, Assam El‐Osta
wiley   +1 more source

Syncope as the Initial Presentation of Takayasu Arteritis in a 57‐Year‐Old Female: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Takayasu arteritis (TA) is a rare chronic granulomatous large‐vessel vasculitis predominantly affecting the aorta and its major branches, leading to stenosis, occlusion, or aneurysm formation. It typically presents in young women, though atypical cases can occur in older adults.
Chao Liu, Jiale Gan, Lili Feng, Yang Yang, Lianwei Dong, Jiabao Liu, Dingguo Zhang   +6 more
wiley   +1 more source

Trial watch: antibody-drug conjugates in cancer therapy. [PDF]

Oncoimmunology
Doffe F, Deng X, Shen Z, Xue E, Schauer K, Kroemer G, Kepp O.   +6 more
europepmc   +1 more source

Integrating antibody–drug conjugates into solid tumor oncology: Current standards and future directions

Cancer, Volume 132, Issue S1, 1 June 2026.
Abstract Antibody–drug conjugates (ADCs) represent a major advance in precision oncology, combining the selectivity of monoclonal antibodies with the cytotoxic potency of chemotherapy. By enabling targeted intracellular delivery of highly potent payloads, ADCs aim to maximize antitumor activity while minimizing systemic toxicity. This review summarizes
André Mansinho, Joana Albuquerque, Andreia Lopes, Emiliano Calvo   +3 more
wiley   +1 more source