Results 101 to 110 of about 2,288,208 (167)

Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains

, 2020
The architectural protein CTCF is a mediator of chromatin conformation, but how CTCF binding to DNA is orchestrated to maintain long-range gene expression is poorly understood.
Peters, TJ (15710243), Achinger-Kawecka, J (15630923), Stirzaker, C (15630950), Smith, GC (15499028), Clark, SJ (15612428), Statham, AL (15612431), Bert, SA (15630941), Parry, AJ (15710246), Du, Q (15650006), Valdes-Mora, F (15710249), Phillippa Taberlay (14750539), French, HJ (15710237), Luu, P-L (15710240), Khoury, A (15710234)   +13 more
core  

Linking DNA-packing density distribution and TAD boundary locations

DNA is heterogeneously packaged into chromatin, which is further organized into topologically associating domains (TADs) with sharp boundaries. These boundary locations are critical for genome regulation.
Sheong, Fu Kit, Meng, Luming, Luo, Qiong
core   +1 more source

Evolutionary and Functional Conservation of Topologically Associating Domain Boundaries in Rice Genomes. [PDF]

Int J Mol Sci
Geyman O, Kurbidaeva A.
europepmc   +1 more source

Two Unrelated Families With Noncoding Duplications Upstream of MSX2 Refine the Critical Regulatory Region Likely Involved in Cranial Bone Development and a Cleidocranial Dysplasia-Like Phenotype. [PDF]

Hum Mutat
Yamada M, Cleghorn M, Krishnamurthy P, French T, Francis D, Kosaki K, Tan TY.   +6 more
europepmc   +1 more source

AxialTAD: an axial contrast architecture for TAD boundary prediction from Hi-C. [PDF]

Brief Bioinform
Choi WY, Rhee JK.
europepmc   +1 more source

Integrating heterogeneity into topologically associating domain boundary prediction in large genomic context in human. [PDF]

NAR Genom Bioinform
Sun Y, Jensen LJ, Tommerup N, Gorodkin J.   +3 more
europepmc   +1 more source

Systematic evaluation of the heterogeneity of topologically associating domain boundaries in a large genomic context in humans. [PDF]

NAR Genom Bioinform
Sun Y, Tommerup N, Jensen LJ, Gorodkin J.   +3 more
europepmc   +1 more source

Identification of differential topologically associating domains from low sequencing depth and pseudobulk chromatin contact maps. [PDF]

Genome Res
Li J, Xu H, Chen H, Lin J, Ye Y, Gao L.
europepmc   +1 more source

Genome-Wide Chromatin Structure Changes During Caste Differentiation in Honeybees. [PDF]

Cells
Zhang X, Lu H, Qu X, Xin L, Wang R, Liang C, Liu X, Chen X.   +7 more
europepmc   +1 more source

Foundation model reveals the shared organization of transcription and topologically associating domains. [PDF]

Cell Syst
Liang H, Berger B, Singh R.
europepmc   +1 more source