Results 141 to 150 of about 2,288,208 (167)

Decoding 3D chromatin architecture reveals distinct enhancer classes underlying hierarchical gene regulation in prostate cancer. [PDF]

Genome Biol
Cao H, Wu Z, Ji B, Yang S, Gonzalez-Smith L, Vu A, Rhie SK.   +6 more
europepmc   +1 more source

Chromatin accessibility classification of TAD boundaries discloses new architectural proteins. [PDF]

Nucleic Acids Res
Jácome-López K, Ledesma-Domínguez L, Esquivel-López A, Pérez-Molina R, Pénagos-Puig A, Aguilar-Lomas A, Gómora-García JC, Furlan-Magaril M.   +7 more
europepmc   +1 more source

RFX5 as a regulator of spatial chromatin contacts and gene expression. [PDF]

Commun Biol
Ge X, Zhang Y, Han Y, Liu X, Jia Z, Liang Y, Wang Y.   +6 more
europepmc   +1 more source

A canonical role of SMAD4 in safeguarding 3D genome architecture to suppress lung tumorigenesis. [PDF]

Oncogene
Xu Y, Han X, Li J, Zhang S, Lian C, Yu C, Xu Z, Zhang Z, Yang B, Ji R, Wang H, Xiao M, Wang Z, Wang B, Chen S, Wang Y, Liu Y, Li S, Shen Z, Lu X, Han X, Zhou Y, Yao Y, Deng J, Guo Y, Wang L, Chen S, Chen X, Chi Y, Yu Y, Tang Y, Kosar M, Fan J, Yang N, Liu J.   +34 more
europepmc   +1 more source

Chromatin insulators in gene regulation and 3D genome organization. [PDF]

Biochem Soc Trans
Sultana H, Kunar R, Matera AG.
europepmc   +1 more source

LAWS-HiC: A Locally Adaptive Weighting and Screening (LAWS) Approach to Improve Detection of Long-Range Chromatin Interactions from Hi-C Data. [PDF]

Methods Protoc
Zhou L, Chen C, Zhao JZ, Hu M, Li Y.
europepmc   +1 more source

Escape from X inactivation varies across genes and tissues and shapes sex-biased sex chromosome gene expression. [PDF]

BMC Genomics
DeCasien AR.
europepmc   +1 more source

Loss of SUMOylation drives aberrant PRC1 clustering and 3D genome rewiring independent of H3K27me3. [PDF]

Nucleic Acids Res
Akilli N, Puel PS, Stefano MD, Muzzopappa F, Fritsch L, Erdel F, Jost D, Cheutin T, Cavalli G.   +8 more
europepmc   +1 more source

Topologically Associating Domain Boundaries That Are Stable Across Diverse Cell Types Are Evolutionarily Constrained and Enriched for Heritability [PDF]

American Journal of Human Genetics, 2021
Topologically associating domains (TADs) are fundamental units of three-dimensional (3D) nuclear organization. The regions bordering TADs-TAD boundaries-contribute to the regulation of gene expression by restricting interactions of cis-regulatory ...
John Anthony Capra, Evonne McArthur
exaly   +2 more sources

Functional Similarities of Protein-Coding Genes in Topologically Associating Domains and Spatially-Proximate Genomic Regions

Genes, 2022
Topologically associating domains (TADs) are the structural and functional units of the genome. However, the functions of protein-coding genes existing in the same or different TADs have not been fully investigated.
Tong Liu, Zheng Wang, Chenguang Zhao
exaly   +2 more sources