Results 31 to 40 of about 2,288,208 (167)

Image3_Glucocorticoid stimulation induces regionalized gene responses within topologically associating domains.tif

open access: yes, 2023
Transcription-factor binding to cis-regulatory regions regulates the gene expression program of a cell, but occupancy is often a poor predictor of the gene response.
Arnaud Droit (36418)   +10 more
core   +1 more source

Pan-3D genome analysis reveals structural and functional differentiation of soybean genomes

open access: yesGenome Biology, 2023
Background High-order chromatin structure plays important roles in gene regulation. However, the diversity of the three-dimensional (3D) genome across plant accessions are seldom reported.
Lingbin Ni   +11 more
doaj   +1 more source

Image1_Glucocorticoid stimulation induces regionalized gene responses within topologically associating domains.tif

open access: yes, 2023
Transcription-factor binding to cis-regulatory regions regulates the gene expression program of a cell, but occupancy is often a poor predictor of the gene response.
Arnaud Droit (36418)   +10 more
core   +1 more source

Overcoming Artificial Structures in Resolution‐Enhanced Hi‐C Data by Signal Decomposition and Multi‐Scale Attention

open access: yesAdvanced Science, EarlyView.
Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Qinyao Li   +6 more
wiley   +1 more source

Table4_Glucocorticoid stimulation induces regionalized gene responses within topologically associating domains.XLSX

open access: yes, 2023
Transcription-factor binding to cis-regulatory regions regulates the gene expression program of a cell, but occupancy is often a poor predictor of the gene response.
Arnaud Droit (36418)   +10 more
core   +1 more source

Matrix Rigidity Mechanoprimes Microglia for Inflammation Through Cytoskeletal‐to‐Nuclear Signaling and 3D Spatio‐Epigenomic Remodeling

open access: yesAdvanced Science, EarlyView.
Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng   +15 more
wiley   +1 more source

Model of TAD boundaries at the mouse and chicken HoxD cluster.

open access: yes, 2018
(A, B) TAD boundaries at the HoxD locus in mouse (A) and chick (B) limb buds. (A) In the mouse, the boundary is dynamic and moves along a few genes within a window determined by a series of CTCF sites. Accordingly, T-DOM enhancers interact with promoters
Christopher Chase Bolt (6008798)   +5 more
core   +1 more source

Table5_Glucocorticoid stimulation induces regionalized gene responses within topologically associating domains.XLSX

open access: yes, 2023
Transcription-factor binding to cis-regulatory regions regulates the gene expression program of a cell, but occupancy is often a poor predictor of the gene response.
Arnaud Droit (36418)   +10 more
core   +1 more source

Regulation of single-cell genome organization into TADs and chromatin nanodomains. [PDF]

open access: yes, 2020
Super-resolution microscopy identifies sub-topologically associating domain (TAD) nanodomains and intercellular heterogeneity in TAD conformation and insulation.
Cheutin, Thierry   +32 more
core   +1 more source

Table3_Glucocorticoid stimulation induces regionalized gene responses within topologically associating domains.XLSX

open access: yes, 2023
Transcription-factor binding to cis-regulatory regions regulates the gene expression program of a cell, but occupancy is often a poor predictor of the gene response.
Arnaud Droit (36418)   +10 more
core   +1 more source

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