Results 91 to 100 of about 1,018,957 (214)

Nano Borophene as a Programmable 2D Scaffold for Organized DNA Assembly and Long‐Range Energy Transfer

open access: yesAdvanced Functional Materials, EarlyView.
Borophene is introduced as a programmable 2D bio‐interface that organizes DNA through dual boron–sulfur and nucleobase interactions. This molecular architecture enables efficient long‐range nanosurface energy transfer, establishing new design principles for functional nano–bio interfaces and amplification‐free optical biosensing.
Teresa Aditya   +11 more
wiley   +1 more source

HPV16 genome integration does not disrupt host topologically associating domain (TAD) boundaries at the integration site in W12 clones G2 and D2.

open access: yes, 2021
(A, D) Hi-C data for W12 clone G2 is compared to (B, E) Hi-C data for W12 clone D2 using (C, F) an insulation score interpreting the boundaries of topologically associating domains (TADs) for HPV16 integration sites within W12 clone G2 (Chr5: 50–55 Mbp ...
Emma L. A. Drane (11331464)   +11 more
core   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Gene regulation during development in the light of topologically associating domains

open access: yes, 2016
During embryonic development, complex transcriptional programs govern the precision of gene expression. Many key developmental genes are regulated via cis-regulatory elements that are located far away in the linear genome.
François Spitz   +5 more
core   +1 more source

Image1_Glucocorticoid stimulation induces regionalized gene responses within topologically associating domains.tif

open access: yes, 2023
Transcription-factor binding to cis-regulatory regions regulates the gene expression program of a cell, but occupancy is often a poor predictor of the gene response.
Arnaud Droit (36418)   +10 more
core   +1 more source

Understanding Spatial Genome Organization: Methods and Insights

open access: yesGenomics, Proteomics & Bioinformatics, 2016
The manner by which eukaryotic genomes are packaged into nuclei while maintaining crucial nuclear functions remains one of the fundamental mysteries in biology.
Vijay Ramani, Jay Shendure, Zhijun Duan
doaj   +1 more source

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

open access: yesAdvanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi   +2 more
wiley   +1 more source

HIFI: estimating DNA-DNA interaction frequency from Hi-C data at restriction-fragment resolution

open access: yesGenome Biology, 2020
Hi-C is a popular technique to map three-dimensional chromosome conformation. In principle, Hi-C’s resolution is only limited by the size of restriction fragments.
Christopher JF Cameron   +2 more
doaj   +1 more source

Evidence for Itinerant Ferromagnetic Flat Bands Producing Large Transverse Responses

open access: yesAdvanced Materials, EarlyView.
Itinerant ferromagnetic flat bands are demonstrated in GdCo5 with a high Curie temperature of 940K, a stacked honeycomb–kagome lattice, through angle‐resolved photoemission spectroscopy and magneto‐thermoelectric measurements. These topological flat bands generate large Berry curvaturte, producing gigantic anomalous Nernst effect with record‐high ...
Susumu Minami   +15 more
wiley   +1 more source

Topologically defined classes of going-down domains

open access: yes, 1976
Let R be an integral domain. Our purpose is to study GD (going-down) domains which arise topologically; that is, we investigate how certain going-down assumptions on R and its overrings relate to the topological space Spec
Ira J. Papick
core   +1 more source

Home - About - Disclaimer - Privacy