Results 71 to 80 of about 5,441 (220)

From Photoalignment to Structured Light: Liquid Crystal Platforms for Beam Shaping and Complex Wavefronts

open access: yesAdvanced Functional Materials, EarlyView.
Photoaligned and photopatterned liquid crystal platforms provide programmable control of optical phase, polarization, and spin‐orbit interactions, enabling compact generation of structured light and complex wavefronts. This review highlights how tailored molecular orientations transform simple beams into designed optical fields, opening versatile ...
Le Zhou   +6 more
wiley   +1 more source

Large scale genomic reorganization of topological domains at the HoxD locus

open access: yesGenome Biology, 2017
Background The transcriptional activation of HoxD genes during mammalian limb development involves dynamic interactions with two topologically associating domains (TADs) flanking the HoxD cluster.
Pierre J. Fabre   +6 more
doaj   +1 more source

Effect of Optical Illumination on Bubble Nanodomains

open access: yesAdvanced Functional Materials, EarlyView.
Stable surface‐confined nanoscale bubble domains are created and manipulated in PMN‐PT single crystals. Under above‐bandgap illumination, these bubble nanodomains remain unchanged. However, upon illumination cessation, they rapidly expand to switch the entire crystal surface, due to the accumulation of a large reservoir of electrons at the crystal ...
Haoze Zhang   +8 more
wiley   +1 more source

Insulator-based loops mediate the spreading of H3K27me3 over distant micro-domains repressing euchromatin genes

open access: yesGenome Biology, 2020
Background Chromosomes are subdivided spatially to delimit long-range interactions into topologically associating domains (TADs). TADs are often flanked by chromatin insulators and transcription units that may participate in such demarcation. Remarkably,
Alexandre Heurteau   +6 more
doaj   +1 more source

Tales from topographic oceans: topologically associated domains and cancer [PDF]

open access: yesEndocrine-Related Cancer, 2019
The 3D organization of the genome within the cell nucleus has come into sharp focus over the last decade. This has largely arisen because of the application of genomic approaches that have revealed numerous levels of genomic and chromatin interactions, including topologically associated domains (TADs). The current review examines how these domains were
openaire   +2 more sources

Three‐Dimensional Biomimetic Aerogel Conduits with Electro‐Ionic‐Immune Coupling Reverse the Pathological Cascade of Spinal Cord Injury

open access: yesAdvanced Functional Materials, EarlyView.
A biomimetic aerogel conduit was engineered from a nanofiber of gelatin/poly(l‐lactic acid) doped with polypyrrole nanoparticles, integrated with tannic acid and Mg2+. This “electro‐ionic‐immune” strategy mimicked spinal cord properties, reduced calcium overload, inflammation, oxidative damage, promoted neural stem cell differentiation, suppressed ...
Qingxiang Liu   +9 more
wiley   +1 more source

From Geometry to Function: Programmable Mechanical Response in 3D‐Printed Adipose‐Inspired Soft Metamaterials

open access: yesAdvanced Functional Materials, EarlyView.
Geometry‐driven design of soft cellular metamaterials is systematically investigated by combining experiments, finite element modeling, and statistical prediction. The study quantifies how unit cell geometry and material properties govern stiffness, instability, densification, and energy absorption.
Alice Berardo   +4 more
wiley   +1 more source

Extraordinary n‐type Tellurium‐Free Thermoelectric Performance of Y‐Doped BiSe via Synergistic Effect of Vacancies and Band Engineering

open access: yesAdvanced Functional Materials, EarlyView.
Yttrium doping in Sb‐alloyed BiSe synergistically induces Bi vacancies and flattens conduction bands, simultaneously slashing lattice thermal conductivity by 50% and boosting the power factor. The optimized n‐type Bi0.64Sb0.3Y0.06Se delivers a peak zT of 0.91 at 393 K (average zT 0.76, 300–523 K) and an 8‐pair module with 4.6% conversion efficiency ...
Wenhao Xie   +16 more
wiley   +1 more source

InterTADs: Integration of Multi-Omics Data on Topological Associated Domains

open access: yes, 2020
Abstract Background: The integration of multi-omics data can greatly facilitate the advancement of research in Life Sciences by providing new insights on how biological systems interact. However, there is currently no widespread procedure for a robust, efficient and meaningful multi-omics data integration; the approach presented here is a first
Nikolaos Pechlivanis   +2 more
openaire   +1 more source

Impact of Disorder on Microscopic Superconducting and Normal‐State Responses in a Kagome Metal

open access: yesAdvanced Functional Materials, EarlyView.
Using depth‐resolved, field‐ and pressure‐dependent μSR$\umu{\rm SR}$ measurements, we show that disorder in Ta‐doped KV3Sb5 drives a crossover from nodal to nodeless superconductivity while strongly modifying the normal‐state magnetic response. Our results reveal that disorder affects superconductivity and magnetism in fundamentally different ways ...
J. N. Graham   +18 more
wiley   +1 more source

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