Results 81 to 90 of about 6,238 (235)
Making sense of the linear genome, gene function and TADs
Epigenetics & Chromatin, 2022 Background Topologically associating domains (TADs) are thought to act as functional units in the genome. TADs co-localise genes and their regulatory elements as well as forming the unit of genome switching between active and inactive compartments.
Helen S. Long +5 more
doaj +1 more source
MeCP2 and transcriptional control of eukaryotic gene expression
European Journal of Cell Biology, 2022 Eukaryotic gene expression is controlled at multiple steps that work in harmony to ensure proper maintenance of cellular morphology and function. Such regulatory mechanisms would include transcriptional gene regulation, which is in turn controlled by ...
Ghanan Bin Akhtar +2 more
doaj +1 more source
, 2021 (A, D) Hi-C data for W12 clone G2 is compared to (B, E) Hi-C data for W12 clone D2 using (C, F) an insulation score interpreting the boundaries of topologically associating domains (TADs) for HPV16 integration sites within W12 clone G2 (Chr5: 50–55 Mbp ...
Emma L. A. Drane (11331464) +11 more
core +1 more source
Advanced Engineering Materials, EarlyView.Coarse‐grained (left) and atomistic (right) models of the shape memory polymer ESTANE ETE 75DT3 are shown schematically. The two representations bridge molecular detail and mesoscopic description. Both models capture shape memory behavior, linking segmental mobility and conformational relaxation of anisotropic chains to macroscopic recovery, and ...
Fathollah Varnik
wiley +1 more source
From Shear to Sound: Mechanics–Acoustics Mapping of TPMS Lattices
Advanced Engineering Materials, EarlyView.Triply periodic minimal surface (TPMS) lattices are mapped across mechanical and acoustic performance, revealing that descriptors validated in compression fail under shear. First‐time comparison with trusses included. A transition from porous to resonance‐driven absorption emerges at 25% density.
Lucía Doyle +3 more
wiley +1 more source
Exploring Curvature Effects in Direct‐Written 3D Curved Hollow Magnetic Nanoshells
Advanced Functional Materials, EarlyView.Fabricated by a hybrid FEBID/CVD method, 3D PtC/Co3Fe core–shell heterostructures with engineered curvature and shell thickness exhibit complex reversal modes with axially symmetric N'eel‐type domain walls. XMCD‐PEEM combined with full‐scale micromagnetic simulations reveal how curvature and thickness govern the domain wall energy landscape and shape ...
Oleksii M. Volkov +10 more
wiley +1 more source
Genome Biology, 2020 Background Chromosomes are subdivided spatially to delimit long-range interactions into topologically associating domains (TADs). TADs are often flanked by chromatin insulators and transcription units that may participate in such demarcation. Remarkably,
Alexandre Heurteau +6 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Moiré band engineering in graphene/hexagonal boron nitride–based superlattices unlocks van Hove singularities (VHSs) for terahertz (THz) optoelectronics. Tuning the Fermi level near these singularities, associated with secondary neutrality points (SNPs), enhances the photothermoelectric response.
Leonid Elesin +16 more
wiley +1 more source
Large scale genomic reorganization of topological domains at the HoxD locus
Genome Biology, 2017 Background The transcriptional activation of HoxD genes during mammalian limb development involves dynamic interactions with two topologically associating domains (TADs) flanking the HoxD cluster.
Pierre J. Fabre +6 more
doaj +1 more source
, 2023 Transcription-factor binding to cis-regulatory regions regulates the gene expression program of a cell, but occupancy is often a poor predictor of the gene response.
Arnaud Droit (36418) +10 more
core +1 more source