Results 101 to 110 of about 14,944,148 (406)
Mitochondrial fatty acid oxidation is stimulated by red light irradiation
FEBS Letters, EarlyView.Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
wiley +1 more source
Total Synthesis of (+)-Macquarimicin A [PDF]
Journal of the American Chemical Society, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
Ryosuke, Munakata +5 more
openaire +2 more sources
A síntese dos sesquiterpenos baquenolidas The synthesis of the bakkenolide sesquiterpenes
Química Nova, 2008 The bakkenolide group of sesquiterpenes has been a focal point of synthetic efforts amongst several research laboratories all linked to our common origins at the Chemistry Institute at the State University in São Paulo.
Timothy John Brocksom +2 more
doaj +1 more source
Ubiquitin-based probes prepared by total synthesis to profile the activity of deubiquitinating enzymes [PDF]
, 2012 Epitope-tagged active-site-directed probes are widely used to visualize the activity of deubiquitinases (DUBs) in cell extracts, to investigate the specificity and potency of small-molecule DUB inhibitors, and to isolate and identify DUBs by mass ...
Berlin, I. +9 more
core +1 more source
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1
FEBS Letters, EarlyView.Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji +5 more
wiley +1 more source
Enantioselective Total Synthesis of (+)-Salvileucalin B [PDF]
, 2011 An enantioselective total synthesis of the diterpenoid natural product (+)-salvileucalin B is reported. Key findings include a copper-catalyzed arene cyclopropanation reaction to provide the unusual norcaradiene core and a reversible retro ...
Levin, Sergiy +2 more
core +1 more source
Enantioselective Total Synthesis of Hyperforin [PDF]
, 2014 A modular, 18-step total synthesis of hyperforin is described. The natural product was quickly accessed using latent symmetry elements, whereby a group-selective, Lewis acid-catalyzed epoxide-opening cascade cyclization was used to furnish the bicyclo[3 ...
Moebius, David C. +2 more
core +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Synthetic studies toward to the first totalsynthesis of Floribundane B
Orbital: The Electronic Journal of Chemistry, 2012 Floribundane B is an iridoid recently isolated by D. I. M. de Mendonça and coworkers from the leaves and the bark of the trunk of Hymenodictyon floribundum B. L. Rob, a plant used in Angola folk medicine to treat fever.
João V. S. Silva +2 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source