Results 101 to 110 of about 14,482,813 (366)
AutoTTS: End-to-End Text-to-Speech Synthesis through Differentiable Duration Modeling [PDF]
arXiv, 2022 Parallel text-to-speech (TTS) models have recently enabled fast and highly-natural speech synthesis. However, they typically require external alignment models, which are not necessarily optimized for the decoder as they are not jointly trained. In this paper, we propose a differentiable duration method for learning monotonic alignments between input ...
arxiv
A new fast method for ceramic foam impregnation: Application to the CCVD synthesis of carbon nanotubes [PDF]
, 2007 A new process that allows preparing, in a single step, good washcoats of catalytic materials for the catalytic chemical vapour deposition (CCVD) synthesis of carbon nanotubes (CNTs) in reticulated ceramic foams is reported. It is shown that the washcoats,
Chartier, Thierry +4 more
core +3 more sources
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
Total Synthesis and Absolute Configuration of the Marine Norditerpenoid Xestenone
Marine Drugs, 2009 Xestenone is a marine norditerpenoid found in the northeastern Pacific sponge Xestospongia vanilla. The relative configuration of C-3 and C-7 in xestenone was determined by NOESY spectral analysis.
Hiroaki Miyaoka +3 more
doaj +1 more source
Neural Speech Synthesis for Estonian [PDF]
arXiv, 2020 This technical report describes the results of a collaboration between the NLP research group at the University of Tartu and the Institute of Estonian Language on improving neural speech synthesis for Estonian. The report (written in Estonian) describes the project results, the summary of which is: (1) Speech synthesis data from 6 speakers for a total ...
arxiv
Synthesis Cost-Optimal Targeted Mutant Protein Libraries [PDF]
arXiv, 2022 Protein variant libraries produced by site-directed mutagenesis are a useful tool utilized by protein engineers to explore variants with potentially improved properties, such as activity and stability. These libraries are commonly built by selecting residue positions and alternative beneficial mutations for each position.
arxiv
Navigating the Chiral Pool in the Total Synthesis of Complex Terpene Natural Products.
Chemical Reviews, 2017 The pool of abundant chiral terpene building blocks (i.e., "chiral pool terpenes") has long served as a starting point for the chemical synthesis of complex natural products, including many terpenes themselves.
Zachary G. Brill +3 more
semanticscholar +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Marine Drugs, 2015 Itralamides A and B were isolated from the lipophilic extract of Lyngbya majuscula collected from the eastern Caribbean. Itralamide B (1) showed cytotoxic activity towards human embryonic kidney cells (HEK293, IC50 = 6 μM).
Xiaoji Wang +8 more
doaj +1 more source
Search and Explore: Symbiotic Policy Synthesis in POMDPs [PDF]
arXiv, 2023 This paper marries two state-of-the-art controller synthesis methods for partially observable Markov decision processes (POMDPs), a prominent model in sequential decision making under uncertainty. A central issue is to find a POMDP controller - that solely decides based on the observations seen so far - to achieve a total expected reward objective.
arxiv