Results 201 to 210 of about 14,944,148 (406)

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

Total Synthesis of Peniterphenyls A and E. [PDF]

open access: yesMar Drugs
Xu H   +6 more
europepmc   +1 more source

The structural chemistry, reactivity, and total synthesis of dolabellane diterpenes

open access: hybrid, 1998
Abimael D. Rodrı́guez   +2 more
openalex   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

Navigating Excess Complexity: Total Synthesis of Daphenylline

open access: green
Brandon A. Wright   +3 more
openalex   +2 more sources

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li   +10 more
wiley   +1 more source

Total Synthesis of Calyciphylline F. [PDF]

open access: yesAngew Chem Int Ed Engl
Sato R   +5 more
europepmc   +1 more source

Antineoplastic Agents. 571. Total Synthesis of Bacillistatin 2

open access: green, 2009
George R. Pettit   +3 more
openalex   +1 more source

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