Results 31 to 40 of about 14,944,148 (406)

Total synthesis of palau’amine [PDF]

Nature Communications, 2015
AbstractPalau’amine has received a great deal of attention in the past two decades as an attractive synthetic target by virtue of its intriguing molecular architecture and significant immunosuppressive activity. Here we report the total synthesis of palau’amine characterized by the construction of an ABDE tetracyclic ring core including a trans-bicylo ...
Namba, Kosuke, Takeuchi, Kohei, Kaihara, Yukari, Oda, Masataka, Nakayama, Akira, Nakayama, Atsushi, Yoshida, Masahiro, Tanino, Keiji   +7 more
openaire   +2 more sources

Total Synthesis of Pyranicin. [PDF]

ChemInform, 2004
[Reaction: see text] A stereocontrolled convergent synthesis of the annonaceous acetogenin pyranicin (1) is presented. Asymmetric Horner-Wadsworth-Emmons (HWE) reactions were used to access key intermediates. The tetrahydropyran derivative 2 was obtained via an asymmetric desymmetrization of the meso-dialdehyde 6, and the butenolide fragment was ...
Daniel, Strand, Tobias, Rein
openaire   +2 more sources

Decision-making regarding total knee replacement surgery: a qualitative meta-synthesis [PDF]

, 2007
Knee osteoarthritis is a highly prevalent condition that can result in disability and reduced quality of life. The evidence suggests that total knee replacement surgery (TKR) is an effective intervention for patients with severe knee problems, but there ...
Jinks, C, O'Neill, T, Ong, BN
core   +3 more sources

Total Synthesis of Aquatolide [PDF]

Organic Letters, 2015
A total synthesis of the sesquiterpene lactone aquatolide has been accomplished. The central step is an intramolecular [2 + 2]-photocycloaddition of an allene onto an α,β-unsaturated δ-lactone. Other key steps are an intramolecular Horner-Wadsworth-Emmons reaction to close the lactone and an intramolecular Mukaiyama-type aldol reaction to cyclize the ...
Saya, J.M., Vos, K., Klein Nijenhuis, R.A., van Maarseveen, J.H., Ingemann, S., Hiemstra, H.   +5 more
openaire   +3 more sources

Total Syntheses of Cathepsin D Inhibitory Izenamides A, B, and C and Structural Confirmation of Izenamide B

Molecules, 2019
The first total syntheses of izenamides A, B, and C, which are depsipeptides inhibitor of cathepsin D, were accomplished. In addition, the stereochemistry of izenamide B was confirmed by our syntheses.
Changjin Lim
doaj   +1 more source

Total Observed Organic Carbon (TOOC): A synthesis of North American observations [PDF]

, 2007
Measurements of organic carbon compounds in both the gas and particle phases measured upwind, over and downwind of North America are synthesized to examine the total observed organic carbon (TOOC) over this region.
Aiken, A. C., Allan, J. D., Apel, E., Atlas, E. L., Baker, A. K., Bates, T. S., Beyersdorf, A. J., Blake, D. R., Campos, T., Coe, H., Crounse, J. D., de Gouw, J. A., DeCarlo, P. F., Dunlea, E. J., Flocke, F. M., Fried, A., Goldan, P., Goldstein, A. H., Griffin, R. J., Heald, C. L., Herndon, S. C., Holloway, J. S., Holzinger, R., Jimenez, J. L., Junkermann, W., Kuster, W. C., Lewis, A. C., Meinardi, S., Millet, D. B., Onasch, T., Polidori, A., Quinn, P. K., Riemer, D. D., Roberts, J. M., Salcedo, D., Sive, B., Swanson, A. L., Talbot, R., Warneke, C., Weber, R. J., Weibring, P., Wennberg, P. O., Wittig, A. E., Worsnop, D. R., Zhang, R., Zheng, J., Zheng, W.   +46 more
core   +7 more sources

Total Synthesis of Herbimycin A [PDF]

Organic Letters, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sophie, Canova, Véronique, Bellosta, Antony, Bigot, Patrick, Mailliet, Serge, Mignani, Janine, Cossy   +5 more
openaire   +2 more sources

Preparation of an advanced intermediate for the synthesis of leustroducsins and phoslactomycins by heterocycloaddition

Beilstein Journal of Organic Chemistry, 2022
A convergent strategy for the synthesis of leustroducsins and phoslactomycins has been designed, relying on the synthesis and the coupling of three main fragments.
Anaïs Rousseau, Guillaume Vincent, Cyrille Kouklovsky   +2 more
doaj   +1 more source

Biologically active Phytophthora mating hormone prepared by catalytic asymmetric total synthesis [PDF]

, 2008
A Phytophthora mating hormone with an array of 1,5-stereogenic centers has been synthesized by using our recently developed methodology of catalytic enantioselective conjugate addition of Grignard reagents. We applied this methodology in a diastereo- and
A. J. Minnaard, B. L. Feringa, Bajpai, Des Mazery, F. Govers, Fabritius, Govers, Harutyunyan, Howell, Judelson, Judelson, K. Bouwmeester, Lamour, Lopez, L  pez, Moreau, Qi, Randall, S. R. Harutyunyan, Smith, T. d. Hartog, van der Lee, van Summeren, Z. Zhao   +23 more
core   +4 more sources

Total Synthesis of Formamicin. [PDF]

ChemInform, 2004
The enantioselective total synthesis of the cytotoxic plecomacrolide natural product formamicin (1) is described. Key aspects of this synthesis include the efficient transacetalation reactions of MOM ethers 28 and 38 to form the seven-membered formyl acetals 29 and 39, a late-stage Suzuki cross-coupling reaction of the highly functionalized vinyl ...
Timothy B, Durham, Nicolas, Blanchard, Brad M, Savall, Noel A, Powell, William R, Roush   +4 more
openaire   +2 more sources