Results 41 to 50 of about 1,840,129 (319)
Total synthesis of panicein A2
Beilstein Journal of Organic Chemistry, 2015 The first total synthesis of the unusual aromatic sesquiterpene panicein A2 is reported and the structure of the natural product has been confirmed. When tested by the NCI against a range of human cancer cell lines, it was found that panicein A2 exhibits
Lili Yeung +4 more
doaj +1 more source
Total Synthesis of (–)-Voacinol and (–)-Voacandimine C
, 2022 We describe the first total synthesis of complex aspidosperma alkaloids (–)-voacinol and (–)-voacandimine C via a late-stage C7-methylenation strategy inspired by a biogenetic hypothesis.
Mohammad , Movassaghi +3 more
core +1 more source
Total Synthesis of (−)-Tuberostemonine [PDF]
Journal of the American Chemical Society, 2002 The first total synthesis of the complex pentacyclic Stemona alkaloid tuberostemonine was accomplished in 24 steps and in 1.4% overall yield from a hydroindole intermediate which is readily obtained in three steps from Cbz-l-tyrosine. An innovative synthetic strategy was applied that relays the single stereocenter of the amino acid precursor into nine ...
Peter, Wipf +2 more
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A Convergent Total Synthesis of (+)-Ineleganolide
, 2023 : We report the total synthesis of the furanobutenolide-derived diterpenoid (+)-ineleganolide. The synthetic approach relies on a convergent strategy, based on the coupling of two enantioenriched fragments which are derived from (-)-linalool and ...
Benjamin , Gross +3 more
core +1 more source
Synthesis, Biosynthesis, and Biological Activity of Diels–Alder Adducts from Morus Genus: An Update
Molecules, 2022 The plants of the Moraceae family are producers of a great variety of polyphenolic natural products. Among these, the Diels–Alder type adducts (DAAs) are endowed with a unique cyclohexene scaffold, since they are biosynthesized from [4+2] cycloaddition ...
Carola Tortora +8 more
doaj +1 more source
Total Synthesis of Loroxanthin
Marine Drugs, 2022 The first total synthesis of loroxanthin (1) was accomplished by Horner-Wadsworth-Emmons reaction of C25-apocarotenal 8 having a silyl-protected 19-hydroxy moiety with C15-phosphonate 25 bearing a silyl-protected 3-hydroxy-ε-end group.
Yumiko Yamano +3 more
doaj +1 more source
Total Synthesis of Callipeltoside A. [PDF]
ChemInform, 2004 A convergent total synthesis of cytotoxic marine macrolide callipeltoside A is described. The synthesis highlights two stereoselective [4 + 2] annulations for the preparation of associated pyran rings.
Hongbing, Huang, James S, Panek
openaire +2 more sources
Total Synthesis of Peshawaraquinone
, 2022 A concise synthesis of a stereochemically complex meroterpenoid, peshawaraquinone, via the unsymmetrical dimerization of its achiral precursor, dehydro-alpha-lapachone, is reported.
Jonathan, George +4 more
core +1 more source
An Expedient Synthesis of the Sugarcane Borer Pheromone Components
Molecules, 1998 A practical synthesis of the title compounds has been developed. The salient features of the synthesis were i) use of easily accessible starting materials viz. aleuritic acid, 10-undecenoic acid, cyclohexanone etc.
Vasant R. Mamdapur +2 more
doaj +1 more source
Marine Drugs, 2022 Reconsideration of the spectroscopic data for penipacids A–E, first reported in 2013 as the acyclic amidines 1–5 from the South China deep sea sediment-derived fungus Penicillium paneum SD-44, prompted a total synthesis structure revision as the ...
Zeinab G. Khalil +2 more
doaj +1 more source