Results 61 to 70 of about 10,668,490 (318)
Total Synthesis of Sordaricin [PDF]
The Journal of Organic Chemistry, 2003 An enantioconvergent total synthesis of sordaricin (3), the diterpene aglycon of an important class of antifungal compounds, is described. Two approaches were explored, the first of which utilized a possible biogenetic intramolecular [4 + 2] cycloaddition to form the complete carbon skeleton of the target molecule as a single regioisomer 30.
Mander, Lewis, Thomson, Regan
openaire +7 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi +9 more
wiley +1 more source
Oxidative radical cyclisations for total synthesis [PDF]
, 2013 Manganese(III) acetate mediated radical cyclisations provide a mild and powerful tool in the construction of complex bicyclic systems. This thesis focuses on the formation of a number of alkenyl substituted [3.3.0]-bicyclic γ-lactones utilising a ...
Ferrara, Steven
core +1 more source
Total Synthesis of Sclerotioloid A [PDF]
, 2023 A four-step total synthesis of a structurally unique N-propargyllated 2,5-diketopiperazine alkaloid sclerotioloid A has been achieved.
Juha, Siitonen
core +2 more sources
Recent advancements in the synthesis of Veratrum alkaloids
Beilstein Journal of Organic ChemistryThe Veratrum alkaloids constitute a class of natural products with particularly intricate polycyclic frameworks and dense stereochemistry and, thus, have stood long as benchmarks in chemical synthesis.
Morwenna Mögel +2 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
A Concise Total Synthesis of (±)-Stepharine and (±)-Pronuciferine [PDF]
, 2022 We herein report a concise total synthesis of (±)-stepharine and (±)-pronuciferine using readily available reagents as the starting materials. This synthesis features a three-component Catellani reaction/Au-catalyzed 6-exo-dig cyclization for the ...
Qianghui, Zhou +4 more
core +2 more sources
Total Synthesis of Cardenolides Acospectoside A and Acovenoside B
MoleculesAcospectoside A (1) and acovenoside B (2), two cytotoxic cardenolides extracted from the venomous South African bush Acokanthera oppositifolia, are distinguished by their unique structural motifs of the l-acovenose moiety at C-3 and a 1β-O-acetylated ...
Benzhang Liu, Peng Xu, Biao Yu
doaj +1 more source
Synthetic Approaches to the Lamellarins—A Comprehensive Review
Marine Drugs, 2014 The present review discusses the known synthetic routes to the lamellarin alkaloids published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins and then focuses on the larger class of the 5,6-saturated and -unsaturated ...
Dennis Imbri +2 more
doaj +1 more source