Results 71 to 80 of about 1,840,129 (319)
Marine Drugs, 2010 The salinosporamides are potent proteasome inhibitors among which the parent marine-derived natural product salinosporamide A (marizomib; NPI-0052; 1) is currently in clinical trials for the treatment of various cancers. Methods to generate this class of
Barbara C. Potts, Kin S. Lam
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Total Synthesis of Antheliolide A [PDF]
Synfacts, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chandra Sekhar, Mushti +2 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Total Synthesis of the Racemate of Laurolitsine
MoleculesThe total synthesis of laurolitsine was achieved for the first time. This reaction was accomplished in 14 steps with a 2.3% yield (this was calculated using 3-hydroxy-4-methoxybenzaldehyde as the starting material) starting from two simple materials, 3 ...
Mingyu Cao +5 more
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Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids
Marine Drugs, 2017 Marine organisms are prolific resources of guanidine-containing natural products with intriguing structures and promising biological activities. These molecules have therefore attracted the attention of chemists and biologists for their further studies ...
Jin Liu, Xu-Wen Li, Yue-Wei Guo
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The Total Synthesis of (+)‐Tedanolide. [PDF]
ChemInform, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Gunnar, Ehrlich +3 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
, 2020 This Structure Data File (SDfile) is associated with the thesis: Clemens, R.T. "The total synthesis of biologically active C-glycoside natural products: 1) total synthesis of (-)-centrolobine 2) total synthesis of (-)-varitriol and analogues 3) progress ...
Scalfani, Vincent F.
core
(−)-Complanine, an inflammatory substance of marine fireworm: a synthetic study
Beilstein Journal of Organic Chemistry, 2009 The synthesis of (−)-complanine, an inflammatory substance of Eurythoe complanata, was accomplished by a “chiral synthon” approach. The absolute configuration of this molecule was determined to be R.
Kazuhiko Nakamura +2 more
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Marine Drugs, 2019 Lissodendrin B is a 2-aminoimidazole alkaloid bearing a (p-hydroxyphenyl) glyoxal moiety that was isolated from the Indonesian sponge Lissodendoryx (Acanthodoryx) fibrosa. We reported the first efficient total synthesis of Lissodendrin B. The precursor 4,
Xianfeng Wei +4 more
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