Results 31 to 40 of about 10,668,490 (318)
Total Synthesis of Dynobactin A [PDF]
, 2023 The first total synthesis of the potent antimicrobial agent dynobactin A is disclosed. This synthesis capitalizes on the hidden symmetry present in this complex decapeptide by enlisting an aziridine ring opening strategy to access b-branched amino acids.
Kelly, Eberle +7 more
core +2 more sources
Total synthesis of (-)-pyridovericin and synthetic studies towards aetheramide B [PDF]
, 2015 In this thesis, two projects involving the total synthesis of natural products are presented. The first part gives an overview on neurodegenerative diseases and introduces the neuritogenic pyridopolyene natural product (–)-pyridovericin.
Schmid, Fabian Felix
core +1 more source
Convergent Total Synthesis of (–)-Cyclopamine [PDF]
, 2023 A concise and enantioselective total synthesis of the Veratrum alkaloid cyclopamine is disclosed. This highly convergent synthesis with a 15-step longest linear sequence (LLS) was enabled by a de novo synthesis of the trans-6,5 hetero-bicycle via a ...
Dongmin, Xu +6 more
core +2 more sources
Total Synthesis of Neohomohalichondrin B [PDF]
, 2023 The total synthesis of neohomohalichondrin B has been achieved using a de novo sequence that enabled a highly convergent pathway to access the C38-C55 thioester fragment.
Rachelle, Quach +2 more
core +2 more sources
Natural Product Communications, 2013 The total synthesis of clusianone was accomplished through the stereoselective construction of a bicyclo[3.3.1]nonane derivative via a three-step sequence which has been utilized for the total syntheses of nemorosone garsubellin A and hyperforin ...
Masahiro Uwamori, Masahisa Nakada
doaj +1 more source
Synthesis of the Enantiomers of Thioridazine
SynOpen, 2020 Thioridazine, a well-known antipsychotic drug, has shown promising effects on several bacterial strains (including Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus).
Simen Antonsen +7 more
doaj +1 more source
Total Synthesis of Ritterazine B [PDF]
, 2021 The first total synthesis of the cytotoxic alkaloid ritterazine B is reported. The synthesis features a unified approach to both steroid subunits, employing a titanium-mediated propargylation reaction to achieve divergence from a common precursor.
Anton V., Dubrovskiy +5 more
core +2 more sources
Total Synthesis of Callipeltoside A. [PDF]
ChemInform, 2004 A convergent total synthesis of cytotoxic marine macrolide callipeltoside A is described. The synthesis highlights two stereoselective [4 + 2] annulations for the preparation of associated pyran rings.
Hongbing, Huang, James S, Panek
openaire +2 more sources
The Total Synthesis of Dragmacidins D and F [PDF]
, 2005 The dragmacidins are an emerging class of bis(indole) natural products isolated from deep-water marine organisms. Although there has been a substantial effort to prepare the simple piperazine dragmacidins, little synthetic work has been done in the area
Garg, Neil Kamal
core +1 more source
Total Synthesis of (±)-Clavubicyclone [PDF]
Organic Letters, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Hisanaka, Ito +3 more
openaire +2 more sources