Results 11 to 20 of about 1,737,350 (269)
Total Synthesis of (+)-Mycalamide A [PDF]
Organic Letters, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Natsuko, Kagawa +2 more
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Total Synthesis of (−)-Callystatin A [PDF]
Organic Letters, 2004 [reaction: see text] A convergent enantioselective synthesis of the natural product (-)-callystatin A (1) is described. Key features of the synthesis include a lipase-mediated kinetic resolution to install the C5 lactone stereochemistry, a hydrozirconation-based approach to the C8-C9 trisubstituted (Z)-olefin, and a stereoselective cross-coupling of a ...
Neil F, Langille, James S, Panek
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Frontiers in Chemistry, 2021 Selectively activating the distal inactive C-H bond for functionalization is one of the on-going challenge in organic synthetic chemistry. In recent years, benefiting from the development of selective synthesis methods, novel methodologies not only make ...
Huang Junrong +11 more
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Total Synthesis of (+)-Cylindramide A [PDF]
Journal of the American Chemical Society, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Amy C, Hart, Andrew J, Phillips
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CHIMIA, 2017 Buruli ulcer, classified as a neglected tropical disease by the World Health Organization, is caused by a mycobacterium which secretes a macrolidic exotoxin called mycolactone A/B.
Sarah Saint-Auret +6 more
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Beilstein Journal of Organic Chemistry, 2022 A convergent strategy for the synthesis of leustroducsins and phoslactomycins has been designed, relying on the synthesis and the coupling of three main fragments.
Anaïs Rousseau +2 more
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The Total Synthesis of (−)-Lemonomycin [PDF]
Journal of the American Chemical Society, 2003 The first total synthesis of the novel glycosylated tetrahydroisoquinoline antitumor antibiotic (-)-lemonomycin has been accomplished (15 steps from 9). The highly convergent synthesis relies on a key asymmetric dipolar cycloaddition to set the stereochemistry of the aglycone core, a Suzuki fragment coupling to connect the diazabicycle to the aryl ...
Ashley, Eric R. +2 more
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Synthetic Advances in Macrosphelides: Natural Anticancer Agents
Molecules, 2014 Total synthesis of macrosphelides is summarized. Synthetic approaches contain the preparation of key fragments and the final ring-closure reaction for unique 16- or 15-membered macrolactone skeletons.
Seung-Mann Paek
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Total Synthesis of (±)-Symbioimine [PDF]
Organic Letters, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Yefen, Zou +2 more
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Tetrahedron Letters, 2022 Remdesivir, the first drug approved by the FDA to treat COVID-19, is in high demand for patients infected with the SARS-CoV-2 virus. Herein, we report a facile approach minimizing the protecting group manipulations to afford remdesivir in good overall yield.
Kumar Palli, Kishore +9 more
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