Results 21 to 30 of about 1,737,350 (269)
Total synthesis of gelsemoxonine [PDF]
Pure and Applied Chemistry, 2011 The first total synthesis of gelsemoxonine has been accomplished. A divinylcyclopropane–cycloheptadiene rearrangement of the highly functionalized substrate successfully assembled the spiro-quaternary carbon center connected to the bicyclic seven-membered core structure.
Jun, Shimokawa +3 more
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The Essence of Total Synthesis [PDF]
ChemInform, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
K C, Nicolaou, Scott A, Snyder
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Natural Product Communications, 2013 The total synthesis of clusianone was accomplished through the stereoselective construction of a bicyclo[3.3.1]nonane derivative via a three-step sequence which has been utilized for the total syntheses of nemorosone garsubellin A and hyperforin ...
Masahiro Uwamori, Masahisa Nakada
doaj +1 more source
Synthesis of the Enantiomers of Thioridazine
SynOpen, 2020 Thioridazine, a well-known antipsychotic drug, has shown promising effects on several bacterial strains (including Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus).
Simen Antonsen +7 more
doaj +1 more source
Total Synthesis of (+)-Superstolide A [PDF]
The Journal of Organic Chemistry, 2008 A convergent and highly stereocontrolled total synthesis of the cytotoxic macrolide (+)-superstolide A is described. Key features of this synthesis include the use of bimetallic linchpin 36b for uniting the C(1)-C(15) (43) and the C(20)-C(27) (38) fragments of the natural product, a late-stage Suzuki macrocyclization of 49, and a highly ...
Mariola, Tortosa +2 more
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Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy
Molecules, 2018 Synthesis of the sex pheromone of the tea tussock moth in 33% overall yield over 10 steps was achieved. Moreover, the chiral pool concept was applied in the asymmetric synthesis.
Hong-Li Zhang +5 more
doaj +1 more source
Total Synthesis of (+)-Lasonolide A [PDF]
Organic Letters, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tomoyuki, Yoshimura +5 more
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Total Synthesis of (−)-Tuberostemonine [PDF]
Journal of the American Chemical Society, 2002 The first total synthesis of the complex pentacyclic Stemona alkaloid tuberostemonine was accomplished in 24 steps and in 1.4% overall yield from a hydroindole intermediate which is readily obtained in three steps from Cbz-l-tyrosine. An innovative synthetic strategy was applied that relays the single stereocenter of the amino acid precursor into nine ...
Peter, Wipf +2 more
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Molecules, 2014 The discovery of a more cytotoxic macrosphelide derivative, including its total synthesis and bioassay are described. Application of the Koide protocol to a readily available propagylic alcohol allowed the rapid and practical synthesis of a macrosphelide
Yu Mi Heo +3 more
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Total Synthesis of Callipeltoside A. [PDF]
ChemInform, 2004 A convergent total synthesis of cytotoxic marine macrolide callipeltoside A is described. The synthesis highlights two stereoselective [4 + 2] annulations for the preparation of associated pyran rings.
Hongbing, Huang, James S, Panek
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