Results 21 to 30 of about 10,668,490 (318)

Novel Strategies in C-H Oxidations for Natural Product Diversification—A Remote Functionalization Application Summary

Frontiers in Chemistry, 2021
Selectively activating the distal inactive C-H bond for functionalization is one of the on-going challenge in organic synthetic chemistry. In recent years, benefiting from the development of selective synthesis methods, novel methodologies not only make ...
Huang Junrong, Huang Junrong, Yang Min, Dai Chuan, Zhou Yajun, Fang Huilong, Zhu Lizhi, Zhu Lizhi, Yin Feng, Yin Feng, Li Zigang, Li Zigang   +11 more
doaj   +1 more source

Total synthesis of gelsemoxonine [PDF]

Pure and Applied Chemistry, 2011
The first total synthesis of gelsemoxonine has been accomplished. A divinylcyclopropane–cycloheptadiene rearrangement of the highly functionalized substrate successfully assembled the spiro-quaternary carbon center connected to the bicyclic seven-membered core structure.
Jun, Shimokawa, Takaaki, Harada, Satoshi, Yokoshima, Tohru, Fukuyama   +3 more
openaire   +2 more sources

A Convergent Total Synthesis of (+)-Ineleganolide [PDF]

, 2023
: We report the total synthesis of the furanobutenolide-derived diterpenoid (+)-ineleganolide. The synthetic approach relies on a convergent strategy, based on the coupling of two enantioenriched fragments which are derived from (-)-linalool and ...
Benjamin , Gross, Seojung , Han, Scott , Virgil, Brian, Stoltz   +3 more
core   +2 more sources

Total Syntheses of Mycolactone A/B and its Analogues for the Exploration of the Biology of Buruli Ulcer

CHIMIA, 2017
Buruli ulcer, classified as a neglected tropical disease by the World Health Organization, is caused by a mycobacterium which secretes a macrolidic exotoxin called mycolactone A/B.
Sarah Saint-Auret, Anne-Caroline Chany, Virginie Casarotto, Cédric Tresse, Lise Parmentier, Hajer Abdelkafi, Nicolas Blanchard   +6 more
doaj   +1 more source

Preparation of an advanced intermediate for the synthesis of leustroducsins and phoslactomycins by heterocycloaddition

Beilstein Journal of Organic Chemistry, 2022
A convergent strategy for the synthesis of leustroducsins and phoslactomycins has been designed, relying on the synthesis and the coupling of three main fragments.
Anaïs Rousseau, Guillaume Vincent, Cyrille Kouklovsky   +2 more
doaj   +1 more source

Synthetic Advances in Macrosphelides: Natural Anticancer Agents

Molecules, 2014
Total synthesis of macrosphelides is summarized. Synthetic approaches contain the preparation of key fragments and the final ring-closure reaction for unique 16- or 15-membered macrolactone skeletons.
Seung-Mann Paek
doaj   +1 more source

The Essence of Total Synthesis [PDF]

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
K C, Nicolaou, Scott A, Snyder
openaire   +2 more sources

Total synthesis of lamellarins D, L, and N [PDF]

, 2006
Total synthesis of cytotoxic marine alkaloids, lamellarins D, L, and N, has been achieved by using Hinsberg-type pyrrole synthesis and palladium-catalyzedSuzuki-Miyaura coupling of the 3,4-dihydroxypyrrole bistriflate 6 as the key reactions.The total ...
Fujikawa, Naotaka, Iwao, Masatomo, Ishibashi, Fumito, Yamaguchi, Tomohiro, Fukuda, Tsutomu, Ohta, Takeshi   +5 more
core   +1 more source

Total Synthesis of Peshawaraquinone [PDF]

, 2022
A concise synthesis of a stereochemically complex meroterpenoid, peshawaraquinone, via the unsymmetrical dimerization of its achiral precursor, dehydro-alpha-lapachone, is reported.
Jonathan, George, David, Huang, Andrew, Lawrence, Tomas, de Castro, Christopher, Sumby   +4 more
core   +2 more sources

Total Synthesis of (+)-Lasonolide A [PDF]

Organic Letters, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tomoyuki, Yoshimura, Fumika, Yakushiji, Shingo, Kondo, Xiaofeng, Wu, Mitsuru, Shindo, Kozo, Shishido   +5 more
openaire   +2 more sources