Results 161 to 170 of about 60,239 (217)

Lupeol-Loaded Liposomes: Triple-Negative Breast Cancer (TNBC) Cytotoxicity and In Vivo Toxicological Evaluation. [PDF]

Chem Biodivers
Soares DCF, Viana DB, de Barros ALB, Mendes Miranda SE, Sachs D, Martins Nunes EH, do Egito EST.   +6 more
europepmc   +1 more source

Expanded characterization of the valproic acid zebrafish larval model of autism spectrum disorder: Insights into dysregulation in the gut

Animal Models and Experimental Medicine, EarlyView.
Meticulous calculation of zebrafish‐equivalent therapeutic valproic acid (VPA) dosage maximized the translational value of the data. Hyposerotonergic tone underpinned an anxiety‐like outcome as a core symptom of autism spectrum disorder (ASD). Compartment‐specific dopaminergic and serotonergic dysregulation in the brain versus gut provided mechanistic ...
Lesha Pretorius, Johanna Adriana Coetzee, Alexio Pedro dos Santos, Carine Smith   +3 more
wiley   +1 more source

In vitro toxicological evaluation of pouched portioned oral nicotine products. [PDF]

Front Toxicol
Keyser BM, Leverette R, McRae R, Wertman J, Shutsky T, Szeliga K, Makena P, Jordan KG.   +7 more
europepmc   +1 more source

Astrocyte SMN Restoration and Forskolin Treatment Improve SMA Synaptic Pathology

Annals of Neurology, EarlyView.
Objective Early phenotypic presentation of central afferent synapse dysfunction within patients with spinal muscular atrophy (SMA) represents a key target for therapeutic development; however, the underlying disease mechanisms remain unresolved. By further investigating motor neuron synapse and peri‐synaptic astrocyte process (PAP) defects in human SMA
Emily Welby, Xiaojie Liu, Melinda Wojtkiewicz, Linda Berg Luecke, Rebekah L. Gundry, Qing‐Song Liu, Allison D. Ebert   +6 more
wiley   +1 more source

<i>In vitro and in vivo</i> toxicological evaluation of 6'-Sialyllactose sodium salt produced by a novel method. [PDF]

Toxicol Rep
Gurung RB, Dolan LC, Arceneaux BG, Go H, Park EJ.   +4 more
europepmc   +1 more source

Toxicological Evaluation, Ultrasound-Assisted Phytochemicals, Antioxidant, GC-MS, FTIR, and In Vivo Analysis of <i>Hibiscus rosa-sinensis</i> Flowers. [PDF]

Food Sci Nutr
Raza H, Sultan MT, Noman AM, Imran A, Bhatti SA, Baig I, Rahim MA, Alsuwat MA, Ramadan MF, Zongo E.   +9 more
europepmc   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Acute and Sub-Chronic Toxicological Evaluation of <i>n</i>-Hexane Fraction of <i>Uvaria chamae</i> Leaves. [PDF]

Afr J Infect Dis
Bamimore VO, Manuel-Mosi ED, Fayehun OO, Olawuni JI, Ogunwole E, Elusiyan CA, Olayiwola G.   +6 more
europepmc   +1 more source

Corrigendum to "<i>In vitro</i> and <i>in vivo</i> toxicological evaluation of 6'-Sialyllactose sodium salt produced by a novel method" [Toxicol. Rep., Volume 15 (2025) 102101]. [PDF]

Toxicol Rep
Gurung RB, Dolan LC, Arceneaux BG, Go H, Park EJ.   +4 more
europepmc   +1 more source

Interfacial Mn‐Carbon Nitride Synergy Enables Selective Photocatalytic C─H Chlorination via Single‐Atom Catalysis

Angewandte Chemie International Edition, EarlyView.
A manganese single‐atom photocatalyst on functionalised carbon nitride enables selective visible‐light‐driven C(sp2)─H chlorination. DFT‐supported mechanistic studies indicate that photoinduced charge separation activates NCS, while isolated Mn sites stabilize Mn─Cl intermediates at the catalyst interface.
Jaro Vanderghinste, Prakash Kumar Sahoo, Xinbang Wu, Thanh Huyen Vuong, Anna Rokicińska, Susanna Monti, Giovanni Barcaro, Alina Skorynina, Aleksander Jaworski, Vivien Michaelis, Jabor Rabeah, Julia Bornhorst, Laura Simonelli, Piotr Kuśtrowski, Adam Slabon, Paul J. Dyson, Shoubhik Das   +16 more
wiley   +1 more source