Results 91 to 100 of about 2,258 (177)
Proteomic Profiling of Pre- and Post-Surgery Saliva of Glioblastoma Patients: A Pilot Investigation. [PDF]
Int J Mol SciGlioblastoma multiforme (GBM) is an extremely aggressive brain tumor characterized by a high infiltration capability and recurrence rate. Early diagnosis is crucial to improve the prognosis and to personalize the therapeutic approach.
Muntiu A +12 more
europepmc +3 more sources
Ruolo del sistema ubiquitina-proteasoma (UPS) nella disfunzione beta cellulare del diabete di tipo 2 e possibili opzioni terapeutiche. [PDF]
, 2011 Ruolo del sistema ubiquitina-proteasoma (UPS) nella disfunzione beta cellulare del diabete di tipo 2 e possibili opzioni terapeutiche. Sebbene la disfunzione beta cellulare rivesta un ruolo di primaria importanza nel diabete di tipo 2, le informazioni ad
BUGLIANI, MARCO
core
PROTEOMICS, Volume 24, Issue 11, June 2024.Abstract Small extracellular vesicles (sEVs) are cell‐derived vesicles evolving as important elements involved in all stages of cancers. sEVs bear unique protein signatures that may serve as biomarkers. Pancreatic cancer (PC) records a very poor survival rate owing to its late diagnosis and several cancer cell‐derived proteins have been reported as ...
Chamini J. Perera +11 more
wiley +1 more source
Role of tumor protein D52 in tumor occurrence and development, and its potential application value in tumor diagnosis and therapy [PDF]
, 2016 肿瘤蛋白D52(TPD52)在乳腺癌、前列腺癌、肺癌、卵巢癌和血液系统恶性病变等多种肿瘤中高表达,可参与肿瘤细胞增殖、侵袭、转移以及抑制DNA修复等生物学行为,并诱导机体产生对肿瘤的保护性免疫,是肿瘤诊断与分子靶向治疗中最有应用前景的候选蛋白之一。笔者对TPD52在肿瘤中发生发展的作用及其在肿瘤诊疗中潜在应用价值进行综述,旨在为TPD52进一步研究指明方向,更好实现其临床价值。Tumor protein D52(TPD52), which is involved in tumor cell ...
周思佳, 陈波, 骆明旭
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Clinical and Translational Medicine, Volume 14, Issue 2, February 2024.AIDPI is a robust biomarker for stratifying high‐risk OSA patients characterized by dysregulated cholesterol homeostasis, and SQLE is a metabolic vulnerability of these patients. Silencing SQLE impedes OSA by reducing cholesterol and inhibiting the FAK/PI3K/Akt/mTOR pathway.
Yongjie Wang +7 more
wiley +1 more source
Generation and characterisation of two D2A1 mammary cancer sublines to model spontaneous and experimental metastasis in a syngeneic BALB/c host [PDF]
, 2017 Studying the complex mechanisms underlying breast cancer metastasis and therapy response necessitates relevant in vivo models, particularly syngeneic models with an intact immune system.
Aslakson +34 more
core +3 more sources
Tumor Proteins D52 and D54 Have Opposite Effects on the Terminal Differentiation of Chondrocytes [PDF]
, 2017 The tumor protein D (TPD) family consists of four members, TPD52, TPD53, TPD54, and TPD55. The physiological roles of these genes in normal tissues, including epidermal and mesenchymal tissues, have rarely been reported.
Chihiro Ito +7 more
core +2 more sources
Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Inter-individual variation in DNA repair capacity: A need for multi-pathway functional assays to promote translational DNA repair research [PDF]
, 2014 Why does a constant barrage of DNA damage lead to disease in some individuals, while others remain healthy? This article surveys current work addressing the implications of inter-individual variation in DNA repair capacity for human health, and discusses
Chaim, Isaac Alexander +2 more
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Cancer Management and Research, 2020 Daoqing Su, Zhengang Ji, Pengfei Xue, Shengfu Guo, Qingbin Jia, Hanyu Sun Department of Neurosurgery, Liaocheng People’s Hospital and Liaocheng Brain Hospital, Liaocheng Hospital Affiliated to Shandong First Medical University, Liaocheng City ...
Su D, Ji Z, Xue P, Guo S, Jia Q, Sun H
doaj