Population frequencies of thiopurine-related pharmacogenes in healthy individuals from Kosovo. [PDF]
Pasha F +6 more
europepmc +1 more source
The IGNITE Pharmacogenetics Working Group: An Opportunity for Building Evidence with Pharmacogenetic Implementation in a Real‐World Setting [PDF]
Beitelshees, AL +26 more
core +1 more source
Acquired Immunodeficiency in Newborn Following Intrauterine Exposure to Thiopurines for Treatment of Inflammatory Bowel Disease. [PDF]
Morand S +7 more
europepmc +1 more source
Validation of diagnostic screening test for pharmacogenomic targets for thiopurine drugs in indian pediatric acute lymphoblastic leukemia patients. [PDF]
Joseph GT +17 more
europepmc +1 more source
Identification of cellular proteome using two-dimensional difference gel electrophoresis in ST cells infected with transmissible gastroenteritis coronavirus [PDF]
core +1 more source
Clinically actionable pharmacogenomic variants for anticancer therapy in Nigeria: first comprehensive variant profiling in underrepresented Nigerian cohorts. [PDF]
Ukpe MP, Ezeanuka AC.
europepmc +1 more source
Pharmacogenetic Analysis of TPMT and NUDT15 in a European Pediatric Cohort with IBD and Autoimmune Diseases: Frequency Data and Clinical Relevance. [PDF]
Pau A +10 more
europepmc +1 more source
硫唑嘌呤治疗系统性红斑狼疮的不良反应与硫嘌呤甲基转移酶活性的关系
【目的】探讨硫唑嘌呤(AZA)在系统性红斑狼疮(SLE)维持治疗中的不良反应(ARD)以及与硫嘌呤甲基转移酶(TPMT)活性的关系。【方法】分析AZA在250例SLE患者维持治疗中的ARD发生特点,并应用高效液相色谱法(HPLC) 测定这部分患者红细胞TPMT 活性,分析TPMT活性与AZA所致不良反应的关系。【结果】最常见的ARD是血液系统损害(21例,8.4%),其次为胃肠道反应(19例,7.6%),肝功能异常(8例,3.2%)、脱发(5例,2.0%),急性胰腺炎1例 ...
doaj

