Results 81 to 90 of about 37,032,341 (244)

Dynamic Electrophoretic Assembly Coupled With Water‐Splitting‐Induced pH Control Enables Precision Ion Sieving Membranes

Advanced Materials, EarlyView.
A green, external‐catalyst‐free route grows defect‐free covalent organic framework membranes directly on ion‐exchange supports using an alternating electric field and in situ‐generated acid. Through a self‐regulating, self‐healing mechanism, the membranes achieve near‐complete, ultra‐fast separation of monovalent ions such as Li+, Na+, and K+, offering
Mohammad Hossein Jandaghian, Petric Marc Ruya, Ipek Ozyurt, Ali Atyabi, Samuel Eyley, Wim Thielemans, Alexander Volodin, Riccardo Alessandri, Xing Yang   +8 more
wiley   +1 more source

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

Advanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen, Matthias Mork, Ramin Nasehi, Vasudha Turuvekere Krishnamurthy, Kira Zeevaert, Aaron Babendreyer, Jacopo Di Russo, Wolfgang Wagner, Laura De Laporte   +8 more
wiley   +1 more source

Methamphetamine Activates Trace Amine Associated Receptor 1 to Regulate Astrocyte Excitatory Amino Acid Transporter-2 via Differential CREB Phosphorylation During HIV-Associated Neurocognitive Disorders

Frontiers in Neurology, 2020
Methamphetamine (METH) use, referred to as methamphetamine use disorder (MUD), results in neurocognitive decline, a characteristic shared with HIV-associated neurocognitive disorders (HAND).
Irma E. Cisneros, Anuja Ghorpade, Kathleen Borgmann   +2 more
doaj   +1 more source

Culinary Chemistry as a Platform for Interfacial Materials Design

Advanced Materials Interfaces, EarlyView.
Culinary processes control interfaces through heating, shear, gelation, and molecular transport. This Review connects selected gastronomic examples with food‐derived nanomaterials, plasmonic sensing, anthocyanin photovoltaics, and intelligent packaging. Original agar‐based plasmonic films illustrate the proposed translation.
Josep Moreno, I. Brian Becerril‐Castro, Irene Calderon‐Gonzalez, Jaslyn Ru Ting Chen, Zhiming Wang, Alexander O. Govorov, José Manuel Romo‐Herrera, Neus Feliu, Wolfgang J. Parak, Miguel A. Correa‐Duarte, In Yee Phang, Xing Yi Ling, Ramón A. Alvarez‐Puebla   +12 more
wiley   +1 more source

Evidence for functional trace amine associated receptor-1 in normal and malignant B cells.

, 2011
Following the observation that dopaminergic components are present in normal and malignant B cells, we now provide evidence that they additionally express the functionally related trace amine-associated receptor-1 (TAAR1).
Gordon, John, Millan, MJ, Wasik, AM, Scanlan, T, Barnes, Nicholas; id_orcid   +4 more
core   +1 more source

Chitin‐Chitosan Cryogels for the Reversible Sequestration and Recovery of Heavy Metals From Wastewater

Advanced Materials Technologies, EarlyView.
Chitin‐chitosan cryogels with degrees of N‐acetylation from 12.2% to 71.4% are fabricated by dissolution, coagulation and lyophilization for the sequestration of heavy metals from water. Colorimetry and differential pulse voltammetry showed controlled adsorption and desorption capacities for As5+, Co2+ and Cu2+, making this material attractive for ...
Marta García‐Castrillo, Maialen Uribarrena, Jorge Sáiz, Guillermo Copello, Erlantz Lizundia   +4 more
wiley   +1 more source

Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor

, 2008
Trace amines are neurotransmitters whose role in regulating invertebrate physiology has been appreciated for many de-cades. Recent studies indicate that trace amines may also play a role in mammalian physiology by binding to a novel family of G protein ...
Robert J. Lefkowitz, Jonathan D. Violin, Salahpour, Ali, Tatyana D. Sotnikova, Sotnikova, Tatyana, Gainetdinov, Raul, Bernard Masri, Barak, Larry,, Violin, Jonathan, Zhang, Xiaodong, Larry S. Barak, Raul R. Gainetdinov, Ali Salahpour, Barak, Larry, S., Caron, Marc, Amy J. Ramsey, Marc G. Caron, Ramsey, Amy, Xiaodong Zhang, Masri, Bernard, Lefkowitz, Robert   +20 more
core   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

BRET biosensors to study GPCR biology, pharmacology and signal transduction

Frontiers in Endocrinology, 2012
Bioluminescence Resonance Energy Transfer (BRET) based biosensors have been extensively used over the last decade to study protein-protein interactions and intracellular signal transduction in living cells.
Ali eSalahpour, Stefano eEspinoza, Bernard eMasri, Vincent eLam, Lawrence eBarak, Raul R Gainetdinov   +5 more
doaj   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source