Results 61 to 70 of about 37,032,341 (244)
Modified Chromenes as Precursors to TAAR Regulators [PDF]
, 2011 200 million people worldwide are living with a thyroid disorder related to a hormonal imbalance. Symptoms of this imbalance include deviations from normal heart rates and metabolic rates.
Lehmann, Jonathan, Hart, Matthew
core
FEBS Open Bio, EarlyView.This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
Frontiers in Pharmacology, 2018 The trace amine-associated receptor 1 (TAAR1) is expressed by dopaminergic neurons, but the precise influence of trace amines upon their functional activity remains to be fully characterized.
Xiaoqun Zhang +11 more
doaj +1 more source
Trace Amine-Associated Receptor 1 Regulates Wakefulness and EEG Spectral Composition [PDF]
Neuropsychopharmacology, 2016 Trace amine-associated receptor 1 (TAAR1) agonists have been shown to have procognitive, antipsychotic-like, anxiolytic, weight-reducing, glucose-lowering, and wake-promoting activities. We used Taar1 knockout (KO) and overexpressing (OE) mice and TAAR1 agonists to elucidate the role of TAAR1 in sleep/wake.
Michael D Schwartz +6 more
openaire +2 more sources
Trace-amine associated receptor 1 and vulnerability to methamphetamine use disorders [PDF]
, 2021 Vulnerability to methamphetamine (MA) use is related to the genetics that mediate the aversive and rewarding effects of MA. According to the most recent research, a gene known as the trace-amine associated receptor 1 (TAAR1) seems to play protective role,
Tonello, Derek
core
From Food to Power: Hydrogel Thermoelectrics for Ingestible Electronics
Advanced Functional Materials, EarlyView.We introduce a fully edible thermoelectric–electrochromic platform that harvests heat from food and converts it into a visible color change. N‐type and p‐type hydrogel thermoelectric generators connected in series power anthocyanin‐based electrochromic displays, demonstrating the feasibility of safe, biodegradable, ingestible systems for on‐food ...
Antonia Georgopoulou +3 more
wiley +1 more source
Investigation of Naturally Occurring Single-Nucleotide Variants in Human TAAR1
Frontiers in Pharmacology, 2017 Activation of trace amine-associated receptor 1 (TAAR1) in endocrine pancreas is involved in weight regulation and glucose homeostasis. The purpose of this study was the identification and characterization of potential TAAR1 variants in patients with ...
Jessica Mühlhaus +16 more
doaj +1 more source
The dopamine metabolite 3-methoxytyramine is a neuromodulator. [PDF]
PLoS ONE, 2010 Dopamine (3-hydroxytyramine) is a well-known catecholamine neurotransmitter involved in multiple physiological functions including movement control. Here we report that the major extracellular metabolite of dopamine, 3-methoxytyramine (3-MT), can induce ...
Tatyana D Sotnikova +8 more
doaj +1 more source
Trace amine receptor in GtoPdb v.2025.3 [PDF]
Trace amine-associated receptors were discovered from a search for novel 5-HT receptors [9], where 15 mammalian orthologues were identified and divided into two families.
Maguire, Janet J. +4 more
core +1 more source
Advanced Functional Materials, EarlyView.Optoelectronic synaptic devices based on solution‐processed molecular telluride GST‐225 phase‐change inks are demonstrated for three‐factor learning. A global optical signal broadcast through a silicon waveguide induces non‐volatile conductance updates exclusively in locally electrically flagged memristors.
Kevin Portner +14 more
wiley +1 more source