Results 11 to 20 of about 966,346 (199)

Transcription Factor-Based Genetic Engineering in Microalgae

Plants, 2021
Sequence-specific DNA-binding transcription factors (TFs) are key components of gene regulatory networks. Advances in high-throughput sequencing have facilitated the rapid acquisition of whole genome assembly and TF repertoires in microalgal species.
Keiichi Mochdia, Shun Tamaki
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CRISPR-Based Genetic Switches and Other Complex Circuits: Research and Application

Life, 2021
CRISPR-based enzymes have offered a unique capability to the design of genetic switches, with advantages in designability, modularity and orthogonality.
Pei Du, Chunbo Lou, Xuejin Zhao, Qihui Wang, Xiangyu Ji, Weijia Wei   +5 more
doaj   +1 more source

Transcription factor competition facilitates self-sustained oscillations in single gene genetic circuits.

PLoS Computational Biology, 2023
Genetic feedback loops can be used by cells to regulate internal processes or to keep track of time. It is often thought that, for a genetic circuit to display self-sustained oscillations, a degree of cooperativity is needed in the binding and unbinding ...
Jasper Landman, Sjoerd M Verduyn Lunel, Willem K Kegel   +2 more
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Disease-associated genetic variants in the regulatory regions of human genes: mechanisms of action on transcription and genomic resources for dissecting these mechanisms

Вавиловский журнал генетики и селекции, 2021
Whole genome and whole exome sequencing technologies play a very important role in the studies of the genetic aspects of the pathogenesis of various diseases.
E. V. Ignatieva, E. A. Matrosova
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Genetic Architecture of Transcription and Chromatin Regulation [PDF]

Genomics & Informatics, 2015
DNA microarray and next-generation sequencing provide data that can be used for the genetic analysis of multiple quantitative traits such as gene expression levels, transcription factor binding profiles, and epigenetic signatures.
Kwoneel Kim, Hyoeun Bang, Kibaick Lee, Jung Kyoon Choi   +3 more
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Comparación de los perfiles de transcripción de pacientes con fiebre de dengue y fiebre hemorrágica por dengue que muestra diferencias en la respuesta inmunitaria y claves en la inmunopatogénesis

Biomédica: revista del Instituto Nacional de Salud, 2010
Introducción. El dengue puede manifestarse como una enfermedad leve o evolucionar hasta una enfermedad grave, llamada fiebre hemorrágica por dengue, cuyos mecanismos de inmunopatogénesis no son claros. Objetivo. Utilizar un análisis de microarreglos para
Natalia Houghton-Triviño, Katherine Martín, Kris Giaya, Jairo A. Rodríguez, Irene Bosch, Jaime E. Castellanos   +5 more
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Fractional dynamics of globally slow transcription and its impact on deterministic genetic oscillation. [PDF]

PLoS ONE, 2012
In dynamical systems theory, a system which can be described by differential equations is called a continuous dynamical system. In studies on genetic oscillation, most deterministic models at early stage are usually built on ordinary differential ...
Kun Wei, Shilong Gao, Suchuan Zhong, Hong Ma   +3 more
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Extraction and Characterization of Fucoidan Derived from Sargassum ilicifolium and Its Biomedical Potential with In Silico Molecular Docking

Applied Sciences, 2022
Fucoidan, a polymer derived from seaweed, poses a broad range of biological applications, and its potential medicinal benefits have been widely studied over the past decade.
Archana Lakshmanan, Balamuralikrishnan Balasubramanian, Viji Maluventhen, Arunkumar Malaisamy, Rathinasamy Baskaran, Wen-Chao Liu, Maruthupandian Arumugam   +6 more
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Impact of Module-X2 and Carbohydrate Binding Module-3 on the catalytic activity of associated glycoside hydrolases towards plant biomass

Scientific Reports, 2017
Cellulolytic enzymes capable of hydrolyzing plant biomass are secreted by microbial cells specifically in response to the carbon substrate present in the environment.
Nandita Pasari, Nidhi Adlakha, Mayank Gupta, Zeenat Bashir, Girish H. Rajacharya, Garima Verma, Manoj Munde, Rakesh Bhatnagar, Syed Shams Yazdani   +8 more
doaj   +1 more source

MedProDB: A database of Mediator proteins

Computational and Structural Biotechnology Journal, 2021
In the last three decades, the multi-subunit Mediator complex has emerged as the key component of transcriptional regulation of eukaryotic gene expression.
Rohan Bhardwaj, Jitendra Kumar Thakur, Shailesh Kumar   +2 more
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