Results 11 to 20 of about 5,008,846 (367)

Marine Antimicrobial Peptides-Based Strategies for Tackling Bacterial Biofilm and Biofouling Challenges

Molecules, 2022
An assemblage nexus of microorganisms enclosed in a composite extracellular polymeric matrix is called as a biofilm. The main factor causing biological fouling, or biofouling, is biofilms. Biofilm-mediated biofouling is a significant detrimental issue in
Anupam Patra, Jhilik Das, Nupur Rani Agrawal, Gajraj Singh Kushwaha, Mrinmoy Ghosh, Young-Ok Son   +5 more
doaj   +1 more source

A novel chromatin-remodeling complex variant, dcPBAF, is involved in maintaining transcription in differentiated neurons

Frontiers in Cell and Developmental Biology, 2023
The Polybromo-associated BAF (BRG1- or BRM-associated factors) (PBAF) chromatin-remodeling complex is essential for transcription in mammalian cells.
Nataliya V. Soshnikova, Nataliya V. Soshnikova, Nataliya V. Soshnikova, Asya M. Azieva, Asya M. Azieva, Nataliya S. Klimenko, Alvina I. Khamidullina, Alexey V. Feoktistov, Alexey V. Feoktistov, Andrey A. Sheynov, Alexander V. Brechalov, Victor V. Tatarskiy, Sofia G. Georgieva   +12 more
doaj   +1 more source

Structural Analysis of (p)ppGpp Reveals Its Versatile Binding Pattern for Diverse Types of Target Proteins

Frontiers in Microbiology, 2020
(p)ppGpp, highly phosphorylated guanosine, are global regulatory nucleotides that modulate several biochemical events in bacterial physiology ranging from core central dogma to various metabolic pathways.
Gajraj Singh Kushwaha, Gajraj Singh Kushwaha, Anupam Patra, Neel Sarovar Bhavesh   +3 more
doaj   +1 more source

Contrasting roles for G-quadruplexes in regulating human Bcl-2 and virus homologues KSHV KS-Bcl-2 and EBV BHRF1

Scientific Reports, 2022
Herpesviruses are known to acquire several genes from their hosts during evolution. We found that a significant proportion of virus homologues encoded by HSV-1, HSV-2, EBV and KSHV and their human counterparts contain G-quadruplex motifs in their ...
Shivani Kumar, Chitteti Ramamurthy, Divya Choudhary, Aashika Sekar, Anupam Patra, Neel Sarovar Bhavesh, Perumal Vivekanandan   +6 more
doaj   +1 more source

Genetic determinants of neuroglobin transcription [PDF]

neurogenetics, 2013
Neuroglobin (NGB) is a neuron-specific vertebrate globin shown to protect against hypoxia, ischemia, oxidative stress and the toxic effects of Amyloid-beta. Following on our and others' results highlighting the importance of NGB expression in disease, we searched for genetic determinants of its expression.
Dimitri Avramopoulos, E. Halper-Stromberg, Ruihua Wang, Susan Spear Bassett, M. Szymanski-Pierce   +4 more
openaire   +3 more sources

Analysis of G-quadruplexes upstream of herpesvirus miRNAs: evidence of G-quadruplex mediated regulation of KSHV miR-K12–1-9,11 cluster and HCMV miR-US33

BMC Molecular and Cell Biology, 2020
Background G-quadruplexes regulate gene expression, recombination, packaging and latency in herpesviruses. Herpesvirus-encoded miRNAs have been linked to important biological functions. The presence and the biological role of G-quadruplexes have not been
Shivani Kumar, Divya Choudhary, Anupam Patra, Neel Sarovar Bhavesh, Perumal Vivekanandan   +4 more
doaj   +1 more source

Transcription of an Expanded Genetic Alphabet [PDF]

Journal of the American Chemical Society, 2009
Expansion of the genetic alphabet with a third base pair would have immediate biotechnology applications and also lay the foundation for a semisynthetic organism with an expanded genetic code. A variety of unnatural base pairs have been shown to be formed efficiently and selectively during DNA replication, and the pairs formed between the unnatural ...
Young Jun Seo, Shigeo Matsuda, Floyd E. Romesberg   +2 more
openaire   +3 more sources

Evaluation of seaweed sulfated polysaccharides as natural antagonists targeting Salmonella typhi OmpF: molecular docking and pharmacokinetic profiling

Beni-Suef University Journal of Basic and Applied Sciences, 2022
Background Salmonella belongs to the Enterobacteriaceae family, a gram-negative, non-spore-forming, rod-shaped, motile, and pathogenic bacteria that transmit through unhygienic conditions.
Malaisamy Arunkumar, Murugan Mahalakshmi, Vairamuthu Ashokkumar, Manikka Kubendran Aravind, Sathaiah Gunaseelan, Verma Mohankumar, Balasubramaniem Ashokkumar, Perumal Varalakshmi   +7 more
doaj   +1 more source

NRF2, a Transcription Factor for Stress Response and Beyond

International Journal of Molecular Sciences, 2020
Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that regulates the cellular defense against toxic and oxidative insults through the expression of genes involved in oxidative stress response and drug detoxification.
Feng He, Xiaoli Ru, T. Wen
semanticscholar   +1 more source

CRISPR-Based Genetic Switches and Other Complex Circuits: Research and Application

Life, 2021
CRISPR-based enzymes have offered a unique capability to the design of genetic switches, with advantages in designability, modularity and orthogonality.
Pei Du, Chunbo Lou, Xuejin Zhao, Qihui Wang, Xiangyu Ji, Weijia Wei   +5 more
doaj   +1 more source