Results 41 to 50 of about 5,008,846 (367)

Functional Characteristics of Gene Expression Motifs with Single and Dual Strategies of Regulation [PDF]

Biomed. Phys. Eng. Express, 2 , 025009(2016), 2016
Transcriptional regulation by transcription factors and post-transcriptional regulation by microRNAs constitute two major modes of regulation of gene expression. While gene expression motifs incorporating solely transcriptional regulation are well investigated, the dynamics of motifs with dual strategies of regulation, i.e., both transcriptional and ...
arxiv   +1 more source

Genetic and Transcriptional Control of Bone Formation [PDF]

Oral and Maxillofacial Surgery Clinics of North America, 2010
An exquisite interplay of developmental cues, transcription factors, and coregulatory and signaling proteins support formation of skeletal elements of the jaw during embryogenesis and dynamic remodeling of alveolar bone in postnatal life. These molecules promote initial condensation of the mesenchyme, commitment of the mesenchymal progenitor to ...
Farah Y. Ghori, Haiyan Chen, Amjad Javed
openaire   +3 more sources

Fractional dynamics of globally slow transcription and its impact on deterministic genetic oscillation. [PDF]

PLoS ONE, 2012
In dynamical systems theory, a system which can be described by differential equations is called a continuous dynamical system. In studies on genetic oscillation, most deterministic models at early stage are usually built on ordinary differential ...
Kun Wei, Shilong Gao, Suchuan Zhong, Hong Ma   +3 more
doaj   +1 more source

Adaptive evolution of transcription factor binding sites [PDF]

, 2004
The regulation of a gene depends on the binding of transcription factors to specific sites located in the regulatory region of the gene. The generation of these binding sites and of cooperativity between them are essential building blocks in the ...
Berg, Johannes, Lässig, Michael, Willmann, Stana   +2 more
core   +4 more sources

Landscape of transcription in human cells

Nature, 2012
Eukaryotic cells make many types of primary and processed RNAs that are found either in specific subcellular compartments or throughout the cells. A complete catalogue of these RNAs is not yet available and their characteristic subcellular localizations ...
S. Djebali, Carrie A. Davis, A. Merkel, A. Dobin, T. Lassmann, A. Mortazavi, Andrea Tanzer, Julien Lagarde, Wei Lin, F. Schlesinger, Chenghai Xue, G. Marinov, Jainab Khatun, B. Williams, C. Zaleski, J. Rozowsky, M. Röder, F. Kokocinski, Rehab F Abdelhamid, T. Alioto, I. Antoshechkin, Michael T. Baer, Nadav S. Bar, P. Batut, K. Bell, I. Bell, S. Chakrabortty, Xian Chen, Jacqueline Chrast, João Curado, T. Derrien, J. Drenkow, E. Dumais, Jacqueline Dumais, R. Duttagupta, E. Falconnet, Meagan Fastuca, Katalin Fejes-Toth, Pedro G. Ferreira, S. Foissac, M. Fullwood, Hui Gao, David Gonzalez, Assaf Gordon, H. Gunawardena, C. Howald, Sonali Jha, Rory Johnson, P. Kapranov, Brandon King, C. Kingswood, O. J. Luo, Eddie Park, K. Persaud, Jonathan B. Preall, Paolo Ribeca, B. Risk, D. Robyr, M. Sammeth, Lorian Schaffer, L. See, Atif Shahab, Jørgen Skancke, A. Suzuki, Hazuki Takahashi, Hagen U. Tilgner, Diane Trout, Nathalie Walters, Huaien Wang, J. Wrobel, Yanbao Yu, Xiaoan Ruan, Y. Hayashizaki, J. Harrow, M. Gerstein, T. Hubbard, A. Reymond, S. Antonarakis, G. Hannon, Morgan C. Giddings, Y. Ruan, B. Wold, Piero Carninci, R. Guigó, T. Gingeras   +84 more
semanticscholar   +1 more source

Transcriptional Regulation of Channelopathies in Genetic and Acquired Epilepsies [PDF]

Frontiers in Cellular Neuroscience, 2020
Epilepsy is a common neurological disorder characterized by recurrent uncontrolled seizures and has an idiopathic "genetic" etiology or a symptomatic "acquired" component. Genetic studies have revealed that many epilepsy susceptibility genes encode ion channels, including voltage-gated sodium, potassium and calcium channels.
Karen M.J. van Loo, Albert J. Becker
openaire   +4 more sources

Structure and function of negative feedback loops at the interface of genetic and metabolic networks [PDF]

, 2006
The molecular network in an organism consists of transcription/translation regulation, protein-protein interactions/modifications and a metabolic network, together forming a system that allows the cell to respond sensibly to the multiple signal molecules
Andersson, Anna M. C., Krishna, Sandeep, Semsey, Szabolcs, Sneppen, Kim   +3 more
core   +4 more sources

Large-scale gene-expression studies and the challenge of multiple sclerosis. [PDF]

, 2002
In multiple sclerosis, a complex neurodegenerative disorder, a combination of genetic and environmental factors results in inflammation and myelin damage.
Baranzini, Sergio E, Hauser, Stephen L
core   +3 more sources

Extraction and Characterization of Fucoidan Derived from Sargassum ilicifolium and Its Biomedical Potential with In Silico Molecular Docking

Applied Sciences, 2022
Fucoidan, a polymer derived from seaweed, poses a broad range of biological applications, and its potential medicinal benefits have been widely studied over the past decade.
Archana Lakshmanan, Balamuralikrishnan Balasubramanian, Viji Maluventhen, Arunkumar Malaisamy, Rathinasamy Baskaran, Wen-Chao Liu, Maruthupandian Arumugam   +6 more
doaj   +1 more source

APETALA2 antagonizes the transcriptional activity of AGAMOUS in regulating floral stem cells in Arabidopsis thaliana. [PDF]

, 2017
APETALA2 (AP2) is best known for its function in the outer two floral whorls, where it specifies the identities of sepals and petals by restricting the expression of AGAMOUS (AG) to the inner two whorls in Arabidopsis thaliana.
Chen, Xuemei, Gao, Zhihong, Huang, Zhigang, Liu, Xigang, Shi, Ting, Xiao, Langtao, You, Chenjiang, Yumul, Rae Eden, Zheng, Binglian   +8 more
core   +1 more source