Results 41 to 50 of about 4,501,017 (312)

A synthetic mammalian electro-genetic transcription circuit [PDF]

open access: yesNucleic Acids Research, 2008
ISSN:0301 ...
Weber, Wilfried   +6 more
openaire   +6 more sources

Embodied Computational Evolution: Feedback Between Development and Evolution in Simulated Biorobots

open access: yesFrontiers in Robotics and AI, 2021
Given that selection removes genetic variance from evolving populations, thereby reducing exploration opportunities, it is important to find mechanisms that create genetic variation without the disruption of adapted genes and genomes caused by random ...
Joshua Hawthorne-Madell   +7 more
doaj   +1 more source

Microbiome analysis of saliva from oral squamous cell carcinoma (OSCC) patients and tobacco abusers with potential biomarkers for oral cancer screening

open access: yesHeliyon, 2023
Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer and accounts for about 95% of all head and neck cancers with high mortality, usually at a late stage.
Bolaji Fatai Oyeyemi   +6 more
doaj  

Dinâmica ativa em sala de aula no ensino-aprendizado da transcrição gênica em ciências da saúde

open access: yesMetodologias e Aprendizado, 2020
A metodologia ativa cria um ambiente propício para que o acadêmico tenha a possibilidade de ser resolutivo frente a um desafio, gerando o perfil profissional que está em consonância com as competências gerais dos profissionais da saúde.
Adroaldo Lunardelli   +1 more
doaj   +1 more source

Rapidly Characterizing the Fast Dynamics of RNA Genetic Circuitry with Cell-Free Transcription–Translation (TX-TL) Systems

open access: yesbioRxiv, 2014
RNA regulators are emerging as powerful tools to engineer synthetic genetic networks or rewire existing ones. A potential strength of RNA networks is that they may be able to propagate signals on timescales that are set by the fast degradation rates of ...

semanticscholar   +1 more source

Transcription as source of genetic heterogeneity in budding yeast

open access: yesYeast, 2023
Transcription presents challenges to genome stability both directly, by altering genome topology and exposing single-stranded DNA to chemical insults and nucleases, and indirectly by introducing potential obstacles to the DNA replication machinery. Such obstacles include the RNA polymerase holoenzyme itself, DNA bound regulatory factors, G-quadruplexes
Baptiste Piguet, Jonathan Houseley
openaire   +2 more sources

Chromatin- and transcription-related factors repress transcription from within coding regions throughout the Saccharomyces cerevisiae genome. [PDF]

open access: yesPLoS Biology, 2008
Previous studies in Saccharomyces cerevisiae have demonstrated that cryptic promoters within coding regions activate transcription in particular mutants.
Vanessa Cheung   +6 more
doaj   +1 more source

Transcription Factors and Plants Response to Drought Stress: Current Understanding and Future Directions

open access: yesFrontiers in Plant Science, 2016
Increasing vulnerability of plants to a variety of stresses such as drought, salt and extreme temperatures poses a global threat to sustained growth and productivity of major crops.
R. Joshi   +7 more
semanticscholar   +1 more source

Genetic Architecture of Transcript-Level Variation in Humans [PDF]

open access: yesThe American Journal of Human Genetics, 2008
We report here the results of testing the pairwise association of 12,747 transcriptional gene-expression values with more than two million single-nucleotide polymorphisms (SNPs) in samples of European (CEPH from Utah; CEU) and African (Yoruba from Ibadan; YRI) ancestry.
Wei Zhang   +10 more
openaire   +3 more sources

Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development

open access: yeseLife, 2017
Many pancreatic transcription factors that are essential for islet cell differentiation have been well characterized; however, because they are often expressed in several different cell populations, their functional hierarchy remains unclear.
A. Churchill   +5 more
semanticscholar   +1 more source

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