Results 61 to 70 of about 4,936,819 (357)

Disembodiment: Reproduction, Transcription, And Trace [PDF]

, 2018
This article poses the question, what is so great about the body? Recent scholarship has emphasized the concept of an embodied cognition and reminded us of the significance of embodiment in musical performance.
Aaron Einbond, Benjamin, Chion, Donin, Einbond, Goldsmith, Kittler, Peirce, Weiwei   +8 more
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme

eLife, 2020
PPP-family phosphatases such as PP1 have little intrinsic specificity. Cofactors can target PP1 to substrates or subcellular locations, but it remains unclear how they might confer sequence-specificity on PP1.
Roman O Fedoryshchak, Magdalena Přechová, Abbey M Butler, Rebecca Lee, Nicola O'Reilly, Helen R Flynn, Ambrosius P Snijders, Noreen Eder, Sila Ultanir, Stephane Mouilleron, Richard Treisman   +10 more
doaj   +1 more source

Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands [PDF]

, 1998
Sequence-specific DNA-binding small molecules that can permeate human cells potentially could regulate transcription of specific genes. Multiple cellular DNA-binding transcription factors are required by HIV type 1 for RNA synthesis.
Baird, Eldon E., Dervan, Peter B., Dickinson, Liliane A., Gottesfeld, Joel M., Gulizia, Richard J., Mosier, Donald E., Trauger, John W.   +6 more
core   +1 more source

PlantTFDB 4.0: toward a central hub for transcription factors and regulatory interactions in plants

Nucleic Acids Res., 2016
With the goal of providing a comprehensive, high-quality resource for both plant transcription factors (TFs) and their regulatory interactions with target genes, we upgraded plant TF database PlantTFDB to version 4.0 (http://planttfdb.cbi.pku.edu.cn ...
Jinpu Jin, Feng Tian, Dechang Yang, Yuqi Meng, Lei Kong, Jingchu Luo, Ge Gao   +6 more
semanticscholar   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Role of FlhF and its domains in the assembly of a polar flagellum in P. aeruginosa

Journal of Bacteriology
FlhF, an SRP GTPase, regulates the polarity and flagellation patterns in various bacteria, including Pseudomonas aeruginosa. FlhF is a multidomain protein that comprises three domains: B, N, and G, or the GTPase domain.
Shikha Raghav, Rohit Prajapati, Deepti Jain   +2 more
doaj   +1 more source

Genome-wide transcription start site profiling in biofilm-grown Burkholderia cenocepacia J2315 [PDF]

, 2015
Background: Burkholderia cenocepacia is a soil-dwelling Gram-negative Betaproteobacterium with an important role as opportunistic pathogen in humans. Infections with B.
Coenye, Tom, Deforce, Dieter, Förstner, Konrad, Sass, Andrea, Van Acker, Heleen, Van Nieuwerburgh, Filip, Vogel, Jörg   +6 more
core   +2 more sources

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek, Lori Wiener, Stephanie Veldhuijzen van Zanten, Donna Johnston, Fyeza Hasan, Adam Rapoport, Nathasha Datoo, Kimberley Widger, Sumit Gupta, Karen Fergus, Anthony K. C. Chan, Alisha Kassam, Emily McCullogh, Dave Lysecki   +13 more
wiley   +1 more source

Transcription–Replication Coordination

Life, 2022
Transcription and replication are the two most essential processes that a cell does with its DNA: they allow cells to express the genomic content that is required for their functions and to create a perfect copy of this genomic information to pass on to ...
Marco Saponaro
doaj   +1 more source