Results 81 to 90 of about 3,535,290 (383)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Speech transcription using MED [PDF]

open access: yes, 2001
MED (Media EDitor) is a program designed to facilitate the transcription of digitized soundfiles into textfiles. It was written by Hans Drexler and Daan Broeder, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.
Lehmann, Katrin
core  

Radial or bilateral? The molecular basis of floral symmetry. [PDF]

open access: yes, 2020
In the plant kingdom, the flower is one of the most relevant evolutionary novelties. Floral symmetry has evolved multiple times from the ancestral condition of radial to bilateral symmetry.
ACETO, SERENA   +2 more
core   +1 more source

Whole genome sequencing of CRISPR/Cas9-engineered NF-κB reporter mice for validation and variant discovery

open access: yesScientific Data
Targeted knockout, mutations, or knock-in of genomic DNA fragments in model organisms have been used widely for functional and cell-tracking studies.
Guruswamy Mahesh   +4 more
doaj   +1 more source

ARTD10/PARP10 Induces ADP-Ribosylation of GAPDH and Recruits GAPDH into Cytosolic Membrane-Free Cell Bodies When Overexpressed in Mammalian Cells

open access: yesChallenges, 2018
Protein ADP-ribosylation is a reversible post-translational modification of cellular proteins that is catalysed by enzymes that transfer one (mono) or several (poly) units of ADP-ribose from β-NAD+ to a specific amino acid of the target protein. The
Emilia Mayo   +9 more
doaj   +1 more source

Structural Transition of the Nucleosome during Transcription Elongation

open access: yesCells, 2023
In eukaryotes, genomic DNA is tightly wrapped in chromatin. The nucleosome is a basic unit of chromatin, but acts as a barrier to transcription. To overcome this impediment, the RNA polymerase II elongation complex disassembles the nucleosome during ...
Tomoya Kujirai   +3 more
doaj   +1 more source

Dynamic competition between transcription initiation and repression: Role of nonequilibrium steps in cell-to-cell heterogeneity [PDF]

open access: yesPhys. Rev. E 92, 022710 (2015), 2015
Transcriptional repression may cause transcriptional noise by a competition between repressor and RNA polymerase binding. Although promoter activity is often governed by a single limiting step, we argue here that the size of the noise strongly depends on whether this step is the initial equilibrium binding or one of the subsequent unidirectional steps.
arxiv   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Disembodiment: Reproduction, Transcription, And Trace [PDF]

open access: yes, 2018
This article poses the question, what is so great about the body? Recent scholarship has emphasized the concept of an embodied cognition and reminded us of the significance of embodiment in musical performance.
Aaron Einbond   +8 more
core   +1 more source

Theoretical analysis of transcription process with polymerase stalling [PDF]

open access: yesarXiv, 2015
Experimental evidences show that in gene transcription, RNA polymerase has the possibility to be stalled at certain position of the transcription template. This may be due to the template damage, or protein barriers. Once stalled, polymerase may backtrack along the template to the previous nucleotide to wait for the repair of the damaged site, or ...
arxiv  

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