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miRNAs Regulate miRNAs: Coordinated Transcriptional and Post-Transcriptional Regulation [PDF]

open access: bronzeCell Cycle, 2006
microRNAs are short single-stranded RNA molecules that negatively regulate gene expression at post-transcriptional level. Recently it has been demonstrated that microRNAs are involved in many physiological processes, including differentiation and development.
Andrea Tuccoli   +2 more
openalex   +4 more sources

Roles of lncRNAs in the transcription regulation of HIV-1 [PDF]

open access: yesBiomedical Journal, 2022
Long noncoding RNAs (LncRNAs) is a class of RNA molecules that are more than 200bp but cannot be translated into proteins. More and more studies have proved that lncRNA plays a crucial role in various biological functions and disease processes, including
Xingzhu Liu   +6 more
doaj   +2 more sources

Regulation of HPV transcription

open access: yesClinics, 2018
Human papillomavirus infection is associated with the development of malignant and benign neoplasms. Approximately 40 viral types can infect the anogenital mucosa and are categorized into high- and low-risk oncogenic human papillomavirus, depending on ...
Aline Lopes Ribeiro   +2 more
doaj   +4 more sources

Transcriptional regulation [PDF]

open access: yesEMBO reports, 2008
Overall, the meeting provided an excellent environment for those interested in transcriptional regulation to interact and to hear about a diverse array of topics, which stimulated lively discussions from the interdisciplinary audience. It was a consensus opinion that the meeting was a great success and it is hoped that the keystone symposia will ...
Jan Tuckermann, Peter Herrlich
  +6 more sources

Transcriptional regulation [PDF]

open access: yesWormBook, 2005
The regulation of transcription in C. elegans shares many similarities to transcription in other organisms. The details of how specific transcription factors bind to target promoters and act as either activators or repressors are still being examined in many cases, but an increasing number of factors and their binding sites are being characterized ...
Peter G, Okkema, Michael, Krause
openaire   +4 more sources

REC domain stabilizes the active heptamer of σ54-dependent transcription factor, FleR from Pseudomonas aeruginosa

open access: yesiScience, 2023
Summary: Motility in Pseudomonas aeruginosa is mediated through a single, polar flagellum, which is essential for virulence, colonization, and biofilm formation.
Pankaj Kumar Sahoo, Sheenu, Deepti Jain
doaj   +1 more source

Metabolic profiling of serum and urine in preeclampsia and gestational diabetes in early pregnancy

open access: yesMedicine in Drug Discovery, 2022
PE and GDM are two major metabolic diseases affecting pregnancy. Individuals suffering from GDM are at an increased risk of developing PE in later gestational stages.
Nupur Rani Agarwal   +3 more
doaj   +1 more source

N-Terminus Plays a Critical Role for Stabilizing the Filamentous Assembly and the Antifungal Activity of Bg_9562

open access: yesMicrobiology Spectrum, 2022
Bg_9562, a prophage tail-like protein was earlier shown to be required for bacterial mycophagy by Burkholderia gladioli strain NGJ1. The purified protein exhibited broad-spectrum antifungal activity; however, the structural and mechanistic details vis-à ...
Pankaj Kumar Sahoo   +5 more
doaj   +1 more source

Marine Antimicrobial Peptides-Based Strategies for Tackling Bacterial Biofilm and Biofouling Challenges

open access: yesMolecules, 2022
An assemblage nexus of microorganisms enclosed in a composite extracellular polymeric matrix is called as a biofilm. The main factor causing biological fouling, or biofouling, is biofilms. Biofilm-mediated biofouling is a significant detrimental issue in
Anupam Patra   +5 more
doaj   +1 more source

Structural Analysis of (p)ppGpp Reveals Its Versatile Binding Pattern for Diverse Types of Target Proteins

open access: yesFrontiers in Microbiology, 2020
(p)ppGpp, highly phosphorylated guanosine, are global regulatory nucleotides that modulate several biochemical events in bacterial physiology ranging from core central dogma to various metabolic pathways.
Gajraj Singh Kushwaha   +3 more
doaj   +1 more source

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