Results 1 to 10 of about 5,538,386 (238)

3D chromatin architecture and transcription regulation in cancer. [PDF]

open access: yesJ Hematol Oncol, 2022
Chromatin has distinct three-dimensional (3D) architectures important in key biological processes, such as cell cycle, replication, differentiation, and transcription regulation.
Deng S, Feng Y, Pauklin S.
europepmc   +2 more sources

m6A RNA modification in transcription regulation. [PDF]

open access: yesTranscription, 2021
RNA modifications are prevalent among all the classes of RNA, regulate diverse biological processes, and have emerged as a key regulatory mechanism in post-transcriptional control of gene expression.
Akhtar J, Lugoboni M, Junion G.
europepmc   +2 more sources

Roles of lncRNAs in the transcription regulation of HIV-1 [PDF]

open access: yesBiomedical Journal, 2022
Long noncoding RNAs (LncRNAs) is a class of RNA molecules that are more than 200bp but cannot be translated into proteins. More and more studies have proved that lncRNA plays a crucial role in various biological functions and disease processes, including
Xingzhu Liu   +6 more
doaj   +2 more sources

REC domain stabilizes the active heptamer of σ54-dependent transcription factor, FleR from Pseudomonas aeruginosa

open access: yesiScience, 2023
Summary: Motility in Pseudomonas aeruginosa is mediated through a single, polar flagellum, which is essential for virulence, colonization, and biofilm formation.
Pankaj Kumar Sahoo, Sheenu, Deepti Jain
doaj   +1 more source

Deciphering the acetylation code of p53 in transcription regulation and tumor suppression

open access: yesOncogene, 2022
Although it is well-established that p53-mediated tumor suppression mainly acts through its ability in transcriptional regulation, the molecular mechanisms of this regulation are not completely understood.
Zhang-chuan Xia   +4 more
semanticscholar   +1 more source

Metabolic profiling of serum and urine in preeclampsia and gestational diabetes in early pregnancy

open access: yesMedicine in Drug Discovery, 2022
PE and GDM are two major metabolic diseases affecting pregnancy. Individuals suffering from GDM are at an increased risk of developing PE in later gestational stages.
Nupur Rani Agarwal   +3 more
doaj   +1 more source

N-Terminus Plays a Critical Role for Stabilizing the Filamentous Assembly and the Antifungal Activity of Bg_9562

open access: yesMicrobiology Spectrum, 2022
Bg_9562, a prophage tail-like protein was earlier shown to be required for bacterial mycophagy by Burkholderia gladioli strain NGJ1. The purified protein exhibited broad-spectrum antifungal activity; however, the structural and mechanistic details vis-à ...
Pankaj Kumar Sahoo   +5 more
doaj   +1 more source

Single-component near-infrared optogenetic systems for gene transcription regulation

open access: yesNature Communications, 2021
Near-infrared (NIR) optogenetic systems for transcription regulation are in high demand because NIR light exhibits low phototoxicity, low scattering, and allows combining with probes of visible range. However, available NIR optogenetic systems consist of
A. A. Kaberniuk   +4 more
semanticscholar   +1 more source

Marine Antimicrobial Peptides-Based Strategies for Tackling Bacterial Biofilm and Biofouling Challenges

open access: yesMolecules, 2022
An assemblage nexus of microorganisms enclosed in a composite extracellular polymeric matrix is called as a biofilm. The main factor causing biological fouling, or biofouling, is biofilms. Biofilm-mediated biofouling is a significant detrimental issue in
Anupam Patra   +5 more
doaj   +1 more source

The concurrence of DNA methylation and demethylation is associated with transcription regulation

open access: yesNature Communications, 2021
The mammalian DNA methylome is formed by two antagonizing processes, methylation by DNA methyltransferases (DNMT) and demethylation by ten-eleven translocation (TET) dioxygenases.
Jiejun Shi   +7 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy