Results 151 to 160 of about 736,695 (298)

The Terminator

open access: yes, 2003
Short essay on The Terminator ...
Tapper, Michael
core  

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

open access: yesAdvanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong   +8 more
wiley   +1 more source

Characterization of a transcription terminator of the procyclin PARP A unit of Trypanosoma brucei.

open access: yes, 1996
The polycistronic procylcin PARP (for procyclic acidic repetitive protein) A transcription unit of Trypanosoma brucei was completely characterized by the mapping of the termination region. In addition to the tandem of procyclin genes and GRESAG 2.1, this
Pays, Etienne   +4 more
core  

BacTermFinder: bacteria-agnostic comprehensive terminator finder using a CNN ensemble

open access: yes
Terminator is a region in the DNA that ends the transcription process. Knowing the location of bacterial terminators will lead to a better understanding of how bacteria’s transcription works.
Taheri Ghahfarokhi, Seyed Mohammad Amin
core   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

open access: yesAdvanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong   +14 more
wiley   +1 more source

The terminator saga

open access: yes, 1998
The terminator concept and its impending consequences in agriculture have been hitting our daily newspaper headlines. The terminator gene if expressed within a seed, will mark the death of the seed and the target can be cotton, millets, rice, wheat or ...
Gopinathan, KP
core  

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