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Duck plague caused by the duck plague virus (DPV) is an infectious disease that seriously harms the waterfowl breeding industry. The VP16 protein of α herpesvirus can bind to specific cis-acting elements upstream of the promoter of the immediate-early ...
Tong Zhou +58 more
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Anthocyanin biosynthesis is affected by light, temperature, and other environmental factors. The regulation mode of light on anthocyanin synthesis in apple, pear, tomato and other species has been reported, while not clear in potato.
Xijuan Zhao +9 more
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Ligand-induced shifts in conformational ensembles that describe transcriptional activation
Nuclear receptors function as ligand-regulated transcription factors whose ability to regulate diverse physiological processes is closely linked with conformational changes induced upon ligand binding.
Sabab Hasan Khan +5 more
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Panax notoginseng (Burk) F.H. Chen is a rare and valuable Chinese herb, but root rot mainly caused by Fusarium solani severely affects the yield and quality of P. notoginseng herbal materials. In this study, we isolated 30 P.
Lilei Zheng +13 more
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Transcriptional Activation: Tuning-up transcription [PDF]
Eukaryotic transcription is a complex process, and recent results identify multiple steps that need to be stimulated to activate transcription, one of which is a change in conformation of the general transcription factor TFIIB.
Sheldon, Michael, Danny, Reinberg
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CRISPR-Based Approaches for Gene Regulation in Non-Model Bacteria
CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa) have become ubiquitous approaches to control gene expression in bacteria due to their simple design and effectiveness.
Stephanie N. Call +3 more
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Role of estrogen receptor coregulators in endocrine resistant breast cancer
Breast cancer (BC) is the most ubiquitous cancer in women. Approximately 70–80% of BC diagnoses are positive for estrogen receptor (ER) alpha (ERα).
Kristin A. Altwegg, Ratna K. Vadlamudi
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MYB superfamily is one of the most abundant families in plants, and plays critical role in plant growth, development, metabolism regulation, and stress response.
Qiuhui Wei +17 more
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