Results 51 to 60 of about 5,966,093 (336)

Isolation and Functional Analysis of the bZIP Transcription Factor Gene TaABP1 from a Chinese Wheat Landrace

Journal of Integrative Agriculture, 2012
In plants, basic leucine zipper (bZIP) transcription factors play important roles in regulatory processes, including stress response, pathogenic defense and light response as well as organ and tissue differentiation.
Xin-you CAO, Ming CHEN, Zhao-shi XU, Yao-feng CHEN, Lian-cheng LI, Yue-hua YU, Yang-na LIU, You-zhi MA   +7 more
doaj   +1 more source

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene.

Cancer Cell, 2003
Hypoxia unleashes the invasive and metastatic potential of tumor cells by largely unknown mechanisms. The Met tyrosine kinase, a high affinity receptor for hepatocyte growth factor (HGF), plays a crucial role in controlling invasive growth and is often ...
Selma Pennacchietti, P. Michieli, M. Galluzzo, M. Mazzone, S. Giordano, P. Comoglio   +5 more
semanticscholar   +1 more source

Selective Activation of Alternative MYC Core Promoters by Wnt-Responsive Enhancers. [PDF]

, 2018
In Metazoans, transcription of most genes is driven by the use of multiple alternative promoters. Although the precise regulation of alternative promoters is important for proper gene expression, the mechanisms that mediates their differential ...
Bardales, Jorge A, Darzacq, Xavier, Kawaji, Hideya, Murakawa, Yasuhiro, Wieser, Evin   +4 more
core   +3 more sources

Spontaneous virus reactivation in cattle chronically infected with bovine leukemia virus

BMC Veterinary Research, 2019
Background The absence of virus expression during the chronic stage of bovine leukemia virus (BLV) infection and its reactivation upon ex vivo culture has become a long-lived Dogma.
Juan Pablo Jaworski, Marcos Iván Petersen, Hugo Adrián Carignano, Karina Gabriela Trono   +3 more
doaj   +1 more source

Manipulation of the Plant Host by the Geminivirus AC2/C2 Protein, a Central Player in the Infection Cycle

Frontiers in Plant Science, 2020
Geminiviruses are a significant group of emergent plant DNA viruses causing devastating diseases in food crops worldwide, including the Southern United States, Central America and the Caribbean.
Jennifer Guerrero, Elizabeth Regedanz, Liu Lu, Jianhua Ruan, David M. Bisaro, Garry Sunter   +5 more
doaj   +1 more source

Turning off the switch in medulloblastoma. The inhibitory acetylation of an oncogene [PDF]

, 2010
[No abstract ...
CANETTIERI, Gianluca, CONI, SONIA, DI MARCOTULLIO, LUCIA, GRECO, Azzura, GULINO, Alberto   +4 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The Role of VP16 in the Life Cycle of Alphaherpesviruses

Frontiers in Microbiology, 2020
The protein encoded by the UL48 gene of alphaherpesviruses is named VP16 or alpha-gene-transactivating factor (α-TIF). In the early stage of viral replication, VP16 is an important transactivator that can activate the transcription of viral immediate ...
Dengjian Fan, Dengjian Fan, Dengjian Fan, Mingshu Wang, Mingshu Wang, Mingshu Wang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Renyong Jia, Renyong Jia, Renyong Jia, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Dekang Zhu, Dekang Zhu, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Xumin Ou, Xumin Ou, Xumin Ou, Sai Mao, Sai Mao, Sai Mao, Qun Gao, Qun Gao, Qun Gao, Di Sun, Di Sun, Di Sun, Xingjian Wen, Xingjian Wen, Xingjian Wen, Yunya Liu, Yunya Liu, Yunya Liu, Yanling Yu, Yanling Yu, Yanling Yu, Ling Zhang, Ling Zhang, Ling Zhang, Bin Tian, Bin Tian, Leichang Pan, Leichang Pan, Xiaoyue Chen, Xiaoyue Chen, Xiaoyue Chen   +62 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway. [PDF]

, 2017
Recent studies have linked branched-chain amino acid (BCAA) with numerous metabolic diseases. However, the molecular basis of BCAA's roles in metabolic regulation remains to be established.
Dong, Weibing, Liu, Yunxia, Shao, Jing, Sun, Haipeng, Wang, Yibin, Zhou, Meiyi   +5 more
core   +2 more sources