Results 51 to 60 of about 5,670,610 (287)

Histone Methylation and Memory of Environmental Stress

Cells, 2019
Cellular adaptation to environmental stress relies on a wide range of tightly controlled regulatory mechanisms, including transcription. Changes in chromatin structure and organization accompany the transcriptional response to stress, and in some cases ...
Paola Fabrizio, Steven Garvis, Francesca Palladino   +2 more
doaj   +1 more source

Light Affects Salt Stress-Induced Transcriptional Memory of P5CS1 in Arabidopsis

Proceedings of the National Academy of Sciences of the United States of America, 2016
Jing Bo Jin, Qing Fang Lin
exaly   +2 more sources

Priming of transcriptional memory responses via the chromatin accessibility landscape in T cells [PDF]

, 2017
Memory T cells exhibit transcriptional memory and "remember" their previous pathogenic encounter to increase transcription on re-infection. However, how this transcriptional priming response is regulated is unknown.
Christopher R. Sutton, Denyer, Gareth, Sutton, Christopher R., HARDY, Kris, Dunn, J, Seddiki, N, Turner, SJ, Khanna, R, Morris, Melanie, Melanie Morris, Hardy, K, Sudha Rao, Abel Tan, Rajiv Khanna, Rao, S, Rao, Sudha, Turner, Stephen J., Tu, WJ, McCuaig, R, Sutton, CR, Sau Kuen Lee, Stephen J. Turner, Nabila Seddiki, SUTTON, Chris, Smith, C, Smith, Corey, TU, Sherry, Li, J, McCuaig, Robert, Tan, A, Jasmine Li, Kristine Hardy, Dunn, Jenny, Jenny Dunn, Li, Jasmine, Vedran Brezar, Lee, Sau Kuen, Lee, Sau, Hardy, Kristine, Corey Smith, Khanna, Rajiv, Morris, M, Lee, SK, Gareth Denyer, Robert McCuaig, Wen Juan Tu, Brezar, Vedran, Denyer, G, Tan, Abel, Brezar, V, Tu, Wen Juan, Seddiki, Nabila, Sutton, Christopher, Turner, Stephen J.; id_orcid   +53 more
core   +2 more sources

Epigenetic memory in gene regulation and immune response [PDF]

, 2020
Cells must fine-tune their gene expression programs for optimal cellular activities in their natural growth conditions. Transcriptional memory, a unique transcriptional response, plays a pivotal role in faster reactivation of genes upon environmental ...
이지은, 김태수
core   +2 more sources

CSN5A Subunit of COP9 Signalosome Is Required for Resetting Transcriptional Stress Memory after Recurrent Heat Stress in Arabidopsis

Biomolecules, 2021
In nature, plants are exposed to several environmental stresses that can be continuous or recurring. Continuous stress can be lethal, but stress after priming can increase the tolerance of a plant to better prepare for future stresses.
Amit Kumar Singh, Shanmuhapreya Dhanapal, Alin Finkelshtein, Daniel A. Chamovitz   +3 more
doaj   +1 more source

Transcriptional memory at the nuclear periphery [PDF]

Current Opinion in Cell Biology, 2009
A number of inducible yeast genes are targeted to the nuclear periphery upon transcriptional activation. However, when repressed again, the INO1 and GAL1 genes remain at the nuclear periphery for multiple generations. Retention at the nuclear periphery represents a novel type of transcriptional memory; the peripherally localized, recently repressed ...
openaire   +2 more sources

Reconciling Epigenetic Memory and Transcriptional Responsiveness [PDF]

Cell Systems, 2017
The molecular basis of cellular memory is important but poorly understood. Using estimates of histone dynamics, Martin Howard and colleagues construct a mathematical model that helps to explain both the stability and flexibility of Polycomb-mediated gene regulation in cellular memory.
Fisher, AG, Stumpf, MPH, Merkenschlager, M   +2 more
openaire   +3 more sources

Role of chromatin states in transcriptional memory [PDF]

Biochimica et Biophysica Acta (BBA) - General Subjects, 2009
Establishment of cellular memory and its faithful propagation is critical for successful development of multicellular organisms. As pluripotent cells differentiate, choices in cell fate are inherited and maintained by their progeny throughout the lifetime of the organism.
Sharmistha, Kundu, Craig L, Peterson
openaire   +2 more sources

Roles and Transcriptional Responses of Inhibitory Neurons in Learning and Memory

Frontiers in Molecular Neuroscience, 2021
Increasing evidence supports a model whereby memories are encoded by sparse ensembles of neurons called engrams, activated during memory encoding and reactivated upon recall.
Corinna Giorgi, Corinna Giorgi, Silvia Marinelli   +2 more
doaj   +1 more source

Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation [PDF]

, 2018
Memory T cells are characterized by their rapid transcriptional programs upon re-stimulation. This transcriptional memory response is facilitated by permissive chromatin, but exactly how the permissive epigenetic landscape in memory T cells integrates ...
Li, J, Zaunders, JJ, Sutcliffe, EL, Munier, CML, Dunn, J, Tan, A, Theodoratos, A, Seddiki, N, Turner, SJ, Kelleher, AD, Hardy, K, Zafar, A, Zerweck, J, Xu, Y, Phetsouphanh, Chansavath, Casarotto, MG, Rao, S, Milburn, PJ, Tu, WJ, McCuaig, R, Brezar, V, Phetsouphanh, C, Sutton, CR, Knaute, T, Lim, PS, Masch, A   +25 more
core   +3 more sources