Results 21 to 30 of about 40,064,733 (237)

Genome-wide association study of receptive language ability of 12 year olds [PDF]

open access: yes, 2013
Purpose: We have previously shown that individual differences in measures of receptive language ability at age 12 are highly heritable. The current study attempted to identify some of the genes responsible for the heritability of receptive language ...
Hanscombe, K.B.   +32 more
core   +1 more source

Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology [PDF]

open access: yes, 2022
To identify genetic determinants of airway dysfunction, we performed a transcriptome-wide association study for asthma by combining RNA-seq data from the nasal airway epithelium of 681 children, with UK Biobank genetic association data.
Fairbanks-Mahnke, Ana   +38 more
core   +1 more source

Genome-wide association and functional follow-up reveals new loci for kidney function [PDF]

open access: yes, 2012
Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide association studies in up to 130,600 European ancestry participants overall, and stratified for key CKD risk factors. We uncovered 6 new
Döring, Angela   +999 more
core   +2 more sources

Integrative analysis of transcriptome-wide association study and gene expression profiling identifies candidate genes associated with stroke [PDF]

open access: yesPeerJ, 2019
Background Stroke is a major public health burden worldwide. Although genetic variation is known to play a role in the pathogenesis of stroke, the specific pathogenic mechanisms are still unclear.
Jian Yang   +10 more
doaj   +2 more sources

Transcriptome-Wide Association Studies and Integration Analysis of mRNA Expression Profiles Identify Candidate Genes and Pathways Associated With Ankylosing Spondylitis

open access: yesFrontiers in Immunology, 2022
This study aimed to identify susceptibility genes and pathways associated with ankylosing spondylitis (AS) by integrating whole transcriptome-wide association study (TWAS) analysis and mRNA expression profiling data.
Ruoyang Feng   +4 more
doaj   +1 more source

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure [PDF]

open access: yes, 2011
Numerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans1, 2, 3. We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N =
Döring, Angela   +999 more
core   +2 more sources

Nuclear RNA sequencing of the mouse erythroid cell transcriptome [PDF]

open access: yes, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Umlauf David   +39 more
core   +2 more sources

Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. [PDF]

open access: yes, 2011
The prevalence of hypertension in African Americans (AAs) is higher than in other US groups; yet, few have performed genome-wide association studies (GWASs) in AA.
Keating, BJ   +999 more
core   +2 more sources

Additional file 3 of Transcriptome-wide association study identifies new susceptibility genes and pathways for spondyloarthritis

open access: yes, 2023
Additional file 3: Table S1 Top genes selected by transcriptome-wide association study (TWAS ...
Menghao Teng (16939097)   +4 more
core   +1 more source

Transcriptome-wide association and prediction for carotenoids and tocochromanols in fresh sweet corn kernels

open access: yes, 2021
Sweet corn is consistently one of the most highly consumed vegetables in the U.S., providing a valuable opportunity to increase nutrient intake through biofortification.
University of Georgia (17856095)
core  

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