Results 191 to 200 of about 23,538 (242)

Expression of IMD-CBM peptide induces the autophagic degradation of CAV1 (caveolin 1) to inhibit LDL transcytosis and retard diabetic atherosclerosis. [PDF]

Autophagy
Wang L, Jia X, Bai X, Zhao Y, Cheng W, Shu M, Shu Y, Zhang L, Wang R, Jin S.   +9 more
europepmc   +1 more source

The Reality of Active Targeting in Nanomedicine: Promise Versus Performance. [PDF]

Chembiochem
Cellesi F.
europepmc   +1 more source

Breaking the Silent Barrier: Engineering Antibodies for Brain-Targeted Rabies Immunotherapy. [PDF]

Pharmaceutics
Sun C, Xiao L, Guo X, Wang W, Zhang K, Wang L, Lin Z, Tang Z.   +7 more
europepmc   +1 more source

Advances in Machine Learning-Enhanced PBPK Models for Brain-Targeted Drug Delivery via Nanocarriers: A Comprehensive Review. [PDF]

J Funct Biomater
Hu H, Wang Y.
europepmc   +1 more source

Leveraging endogenous proteins to improve cancer nanomedicine delivery.

Nanoscale
Xu Z, Jolly KJ, Zhang F.
europepmc   +1 more source

Dll4 Suppresses Transcytosis for Arterial Blood-Retinal Barrier Homeostasis [PDF]

Circulation Research, 2020
Rationale: Central nervous system has low vascular permeability by organizing tight junction (TJ) and limiting endothelial transcytosis. While TJ has long been considered to be responsible for vascular barrier in central nervous system, suppressed ...
Akiyoshi Uemura, Jee Myung Yang, Junyeop Lee   +2 more
exaly   +2 more sources

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Lung Endothelial Transcytosis

Comprehensive Physiology, 2020
Abstract Transcytosis of macromolecules through lung endothelial cells is the primary route of transport from the vascular compartment into the interstitial space. Endothelial transcytosis is mostly a caveolae‐dependent process that combines receptor‐mediated endocytosis, vesicle trafficking via actin‐cytoskeletal
Joshua H, Jones, Richard D, Minshall
openaire   +2 more sources

Role of Micelle Size in Cell Transcytosis-Based Tumor Extravasation, Infiltration, and Treatment Efficacy

Nano Letters, 2023
Transcytosis-based active transport of cancer nanomedicine has shown great promise for enhancing its tumor extravasation and infiltration and antitumor activity, but how the key nanoproperties of nanomedicine, particularly particle size, influence the ...
Shiqun Shao, Zi-Chen Li, Zhuxian Zhou
exaly   +2 more sources