Results 201 to 210 of about 23,538 (242)
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Transcytosis in Drug Absorption and Distribution
2021The term transcytosis designates the vesicular transcellular transport of molecules from one side of a polarized epithelial or endothelial cell to the other. It is a key process for the absorption and/or distribution of large molecules, e.g., macromolecules, or, in some cases, more complex entities, e.g., nanoscale particles/constructs.Epithelial cell ...
Talevi, Alan, Bellera, Carolina Leticia
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Endothelial transcytosis in health and disease
Cell and Tissue Research, 2008The visionaries predicted the existence of transcytosis in endothelial cells; the cell biologists deciphered its mechanisms and (in part) the molecules involved in the process; the cell pathologists unravelled the presence of defective transcytosis in some diseases.
Lucia-Doina Popov
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Transcytosis and Catabolism of Antibody
Immunologic Research, 2002This review describes the evolution of our knowledge of the transmission of immunoglobulin G (IgG) from mother to infant and the factors which regulate the persistence of IgG in the circulation. These apparently unrelated processes involve the same Fc receptor, FcRn (n = neonatal).
Victor, Ghetie, E Sally, Ward
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Advanced Drug Delivery Reviews, 1998
Vesicular coat proteins mediate the formation of nascent vesicles and select the cargo to be incorporated therein. As additional coat proteins are discovered that regulate vesicular traffic along very specific intracellular pathways, the possibility looms of regulating the intracellular trafficking and targeting of therapeutic agents by modulation of ...
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Vesicular coat proteins mediate the formation of nascent vesicles and select the cargo to be incorporated therein. As additional coat proteins are discovered that regulate vesicular traffic along very specific intracellular pathways, the possibility looms of regulating the intracellular trafficking and targeting of therapeutic agents by modulation of ...
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Transcytosis: Crossing Cellular Barriers
Physiological Reviews, 2003Tuma, Pamela L., and Ann L. Hubbard. Transcytosis: Crossing Cellular Barriers. Physiol Rev 83: 871–932, 2003; 10.1152/physrev.00001.2003.—Transcytosis, the vesicular transport of macromolecules from one side of a cell to the other, is a strategy used by multicellular organisms to selectively move material between two environments without altering the ...
Pamela L, Tuma, Ann L, Hubbard
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Analysis of Transcytosis of CCN2 by Chondrocytes
2016Transcytosis is a mechanism for the transcellular transport of biomolecules. Analysis of transcytosis is frequently performed in cells with distinct polarity, such as brain endothelial cells. However, in cells without evident polarity, analysis of transcytosis has not been performed. Here, we describe a method for analyzing transcytosis of a CCN family
Kazumi, Kawata +2 more
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Transcytosis of Galectin-3 in Mouse Intestine
2022The GlycoLipid-Lectin (GL-Lect) hypothesis provides a conceptual framework to explain how endocytic pits are built in processes of clathrin-independent endocytosis. According to this hypothesis, oligomeric cellular or pathogenic lectins interact with glycosylated plasma membrane lipids in a way such as to drive the formation of tubular endocytic pits ...
Ivashenka, Alena +5 more
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Transcytosis shuts the door for an unwanted guest
Trends in Plant Science, 2013Penetration resistance is a well-described plant defense process, in which SOLUBLE N-ETHYLMALEIMIDE-SENSITIVE-FACTOR ATTACHMENT RECEPTOR (SNARE) proteins have essential roles in membrane fusion processes. Strong focal accumulation of these proteins at the site of attack by powdery mildew fungi has been considered important for their function.
Nielsen, Mads Eggert +1 more
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Transcytosis in cultured proximal tubular cells
The Journal of Membrane Biology, 1986Studies were designed to examine fluid-phase pinocytosis in proximal tubular cells. Canine proximal tubules were obtained from the band IV of Percoll gradient centrifugation of the dispersed renal cortex, and were seeded on collagen-coated polycarbonate membranes. Integrity of monolayers was confirmed by electrophysiologic measurements, and by scanning
M S, Goligorsky, K A, Hruska
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LDL transcytosis by protein membrane diffusion
The International Journal of Biochemistry & Cell Biology, 2004Endothelial cell (EC) cultures of different, selected vascular beds and/or organs were screened for receptor-mediated transport of proteins with a semipermeable filter assay. In SVEC4-10 cells, a mouse lymphoid endothelial cell line, orosomucoid, albumin, insulin and LDL were transcytosed from the apical (luminal) to basal (abluminal) side by a ...
Kuzmenko ES +3 more
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