Results 91 to 100 of about 141,563 (385)

Recent Advances in Microneedle Platforms for Transdermal Drug Delivery Technologies

Polymers, 2021
In many clinical applications, the transdermal route is used as an alternative approach to avoid the significant limitations associated with oral drug delivery.
Sipho Mdanda, P. Ubanako, Pierre P. D. Kondiah, Pradeep Kumar, Y. Choonara   +4 more
semanticscholar   +1 more source

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

Transdermal Drug Delivery Systems: A Focused Review of the Physical Methods of Permeation Enhancement [PDF]

Advanced Pharmaceutical Bulletin
The skin is the body’s largest organ and serves as a site of administration for various medications. Transdermal drug delivery systems have several advantages over traditional delivery systems.
Rifath Sheikh Vaseem, Alison D’cruz, Srishti Shetty, Hafsa -, Aditya Vardhan, Shreya Shenoy R, Shirleen Miriam Marques, Lalit Kumar, Ruchi Verma   +8 more
doaj   +1 more source

New patents on topical anesthetics. [PDF]

, 2014
Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano, CANTISANI, CARMEN, D'ANDREA, Vito, Frascani, F, MACALUSO, LAURA, paolino, giovanni, RICHETTA, Antonio Giovanni   +6 more
core   +1 more source

A Bioresorbable Neural Interface for On‐Demand Thermal Pain Block

Advanced Functional Materials, EarlyView.
Bioresorbable, implantable neural electronics provide dynamic, on‐demand thermal modulation of peripheral nerves for safe, drug‐free pain relief. A microscale thin‐film heater and temperature sensor embedded within biodegradable encapsulants enable precise temperature control via real‐time feedback.
Jeonghwan Park, Hak‐Young Ahn, Minho Seong, Taehoon Kim, Yulin Zhou, Yameng Xu, Jaehee Lee, Ritika Raj Menghani, Yujin Choi, Minsu Park, Nadir Muzaffar, Youngeun Lee, Seung Gi Seo, Jong Uk Kim, Sang Min Won, Jahyun Koo, Elena Aprea, Taeyeon Kim, Ying Yan, Matthew R. MacEwan, Wilson Z. Ray, Raudel Avila, Geumbee Lee, John A. Rogers   +23 more
wiley   +1 more source

Microemulsion-based novel transdermal delivery system of tetramethylpyrazine: preparation and evaluation in vitro and in vivo

International Journal of Nanomedicine, 2011
Ji-Hui Zhao, Li Ji, Hui Wang, Zhi-Qiang Chen, Yong-Tai Zhang, Ying Liu, Nian-Ping FengSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of ChinaObjective: To deliver 2,3,5,6-tetramethylpyrazine ...
Zhao JH, Ji L, Wang H, Chen ZQ, Zhang YT, Liu Y, Feng NP   +6 more
doaj  

Trends in long-term prescribing of dependence forming medicines [PDF]

, 2019
Using patient-level primary care data to estimate the extent to which antidepressant medicines are prescribed to people continuously for long periods of time.
McManus, S., Nguyen, A., Sehmi, R., Smith, N.   +3 more
core  

Beyond Cholinesterase Inhibition. Anti-Inflammatory Role and Pharmacological Profile of Current Drug Therapy for Alzheimer's Disease [PDF]

, 2016
Inflammation is a common response of an individual against either exogenous or endogenous damage. The role of inflammation and of inflammatory cells recently emerged also in the pathogenesis of neurodegenerative disorders. Experimental evidences show how
GIUBILEI, Franco
core   +1 more source

Formulation and Evaluation of Rosuvastatin Calcium Polymeric Nanoparticles-Loaded Transdermal Patch [PDF]

, 2022
Mais Saadallah, Omar Hamid
openalex   +1 more source

Microneedle Arrays Combined with Nanomedicine Approaches for Transdermal Delivery of Therapeutics

Journal of Clinical Medicine, 2021
Organic and inorganic nanoparticles (NPs) have shown promising outcomes in transdermal drug delivery. NPs can not only enhance the skin penetration of small/biomacromolecule therapeutic agents but can also impart control over drug release or target ...
Vahid Alimardani, S. Abolmaali, G. Yousefi, Zahra Rahiminezhad, M. Abedi, A. Tamaddon, S. Ahadian   +6 more
semanticscholar   +1 more source