Results 71 to 80 of about 152,119 (385)

Transdermal Delivery of Drugs with Microneedles—Potential and Challenges

Pharmaceutics, 2015
Transdermal drug delivery offers a number of advantages including improved patient compliance, sustained release, avoidance of gastric irritation, as well as elimination of pre-systemic first-pass effect.
Kevin Ita
doaj   +1 more source

Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]

, 2014
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
core   +1 more source

Transdermal cold atmospheric plasma-mediated immune checkpoint blockade therapy

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Strategies to improve efficacy and reduce side effects of immune checkpoint blockade (ICB) therapy are clinically relevant. Here, we described a transdermal cold atmospheric plasma (CAP)-mediated ICB therapy.
Guojun Chen, Zhitong Chen, Di Wen, Zejun Wang, Hongjun Li, Yi Zeng, G. Dotti, R. Wirz, Zhen Gu   +8 more
semanticscholar   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Solid Microneedles for Transdermal Delivery of Amantadine Hydrochloride and Pramipexole Dihydrochloride

Pharmaceutics, 2015
The aim of this project was to study the influence of microneedles on transdermal delivery of amantadine hydrochloride and pramipexole dihydrochloride across porcine ear skin in vitro.
Mylien T. Hoang, Kevin B. Ita, Daniel A. Bair   +2 more
doaj   +1 more source

New patents on topical anesthetics. [PDF]

, 2014
Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano, CANTISANI, CARMEN, D'ANDREA, Vito, Frascani, F, MACALUSO, LAURA, paolino, giovanni, RICHETTA, Antonio Giovanni   +6 more
core   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Vascular responses of the extremities to transdermal application of vasoactive agents in Caucasian and African descent individuals [PDF]

, 2015
This is an accepted manuscript of an article published by Springer in European Journal of Applied Physiology on 04/04/2015, available online: https://doi.org/10.1007/s00421-015-3164-2 The accepted version of the publication may differ from the final ...
AC Shore, Army Medical surveillance activity, AT Koutsavlis, B Endrich, B Waeber, BJ Kim, C Cardillo, C Cardillo, CC Ungley, CC Ungley, Clare M. Eglin, CM Stein, CM Stein, CR Anderson, CS Thompson-Torgerson, D Bylund, D Miller, DA Rosenbaum, DF Kahn, DL Feairheller, DS Jones, DW DeGroot, E Clark, E Mata-Greenwood, FSC Golden, GA Conway, HA Daanen, HC Parkington, HP Rang, J Gainer, J Jia, J Jia, J Lundberg, James R. House, JE Burgess, JE Ramsay, JM Johnson, JP Noon, K Hope, K Komori, K Sauerstein, KK Griendling, KW Russell, L Ekenvall, L Kalinowski, LA Holowatz, LA Holowatz, M Honda, M Roustit, M Schmelz, M Shibasaki, MA Chotani, MA Chotani, MA Hashmi, Matthew J. Maley, ME Pueyo, Michael J. Tipton, MJ Easter, MJ Maley, MS Taylor, N Melikian, O Wilson, RF Furchgott, RG Hendry, RT Grant, RT Grant, SJ Duffy, SJ Morris, SJ Sarnoff, SR Bailey, T Lewis, TJ Cleophas, TM Mäkinen, WH Candler   +73 more
core   +4 more sources

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

Cyclodextrins in delivery systems: Applications

Journal of Pharmacy and Bioallied Sciences, 2010
Cyclodextrins (CDs) are a family of cyclic oligosaccharides with a hydrophilic outer surface and a lipophilic central cavity. CD molecules are relatively large with a number of hydrogen donors and acceptors and, thus in general, they do not permeate ...
Gaurav Tiwari, Ruchi Tiwari, Awani K Rai
doaj   +1 more source