Results 91 to 100 of about 3,929,037 (185)

Negatively charged phospholipids doped liposome delivery system for mRNA with high transfection efficiency and low cytotoxicity. [PDF]

Drug Deliv, 2023
Wang L, Xing H, Guo S, Cao W, Zhang Z, Huang L, Xin S, Luo Y, Wang Y, Yang J.   +9 more
europepmc   +1 more source

Transfection of mouse neuroblastoma N18TG2 cells with Metafectene Pro reagent

, 2016
A number of reagents that give reasonably good transfection efficiency of mouse neuroblastoma cells have been developed; however, these reagents usually display a toxic action.
Gabriellaaugusti tocco,, ORLANDO, Viviana, I. T. A. L. , Y., Department Of Cell And Developmental Biology “sapienza” University Of Rome,   +3 more
core  

Conjugation of microbial-derived gold nanoparticles to different types of nucleic acids: evaluation of transfection efficiency. [PDF]

Sci Rep, 2023
Pourali P, Dzmitruk V, Benada O, Svoboda M, Benson V.   +4 more
europepmc   +1 more source

The Effect of Cryoprotectants and Storage Conditions on the Transfection Efficiency, Stability, and Safety of Lipid-Based Nanoparticles for mRNA and DNA Delivery. [PDF]

Adv Healthc Mater, 2023
Kafetzis KN, Papalamprou N, McNulty E, Thong KX, Sato Y, Mironov A, Purohit A, Welsby PJ, Harashima H, Yu-Wai-Man C, Tagalakis AD.   +10 more
europepmc   +1 more source

The effect of the histological properties of tumors on transfection efficiency of electrically assisted gene delivery to solid tumors in mice

, 2007
Uniform DNA distribution in tumors is a prerequisite step for high transfection efficiency in solid tumors. To improve the transfection efficiency of electrically assisted gene delivery to solid tumors in vivo, we explored how tumor histological ...
Grosel, A., Mesojednik, S., Pavlin, D., Cemazar, M., Kranjc, S., Sersa, G., Coer, A., Tevz, G.   +7 more
core   +1 more source

Deconvolution of cargo delivery and immunogenicity following intranasal delivery of mRNA lipid nanoparticle vaccines

Molecular Therapy: Nucleic Acids
Intranasal vaccination aims to elicit mucosal immunity in the respiratory tract to better protect against respiratory infections (e.g., SARS-CoV-2 and influenza). Most vaccines, including recent COVID-19 mRNA lipid nanoparticles (LNPs), are optimized for
Mai N. Vu, Devaki Pilapitiya, Andrew Kelly, Marios Koutsakos, Stephen J. Kent, Jennifer A. Juno, Hyon-Xhi Tan, Adam K. Wheatley   +7 more
doaj   +1 more source

Self-Assembled Oleic Acid-Modified Polyallylamines for Improved siRNA Transfection Efficiency and Lower Cytotoxicity. [PDF]

ACS Appl Bio Mater, 2023
Salvador C, Andreozzi P, Romero G, Loinaz I, Dupin D, Moya SE.   +5 more
europepmc   +1 more source

ROS responsive polyethylenimine-based fluorinated polymers for enhanced transfection efficiency and lower cytotoxicity. [PDF]

Bosn J Basic Med Sci, 2022
Hua P, Yang D, Chen R, Qiu P, Chen M.
europepmc   +1 more source

Albumin Incorporation in Polyethylenimine–DNA Polyplexes Influences Transfection Efficiency

, 2016
Polyplexes of plasmid with synthetic polycationic vectors, such as linear polyethylenimine (LPEI), have been widely investigated. While much is known about the role of physicochemical characterization of the polycation in transfection, the role of serum ...
Marie-Isabel Syga (1443166), Esther Kohler (698230), V. Prasad Shastri (394832), Elena Nicolì (1443163)   +3 more
core   +1 more source

Polysaccharide-Polyplex Nanofilm Coatings Enhance Nanoneedle-Based Gene Delivery and Transfection Efficiency. [PDF]

Small, 2022
Hachim D, Zhao J, Bhankharia J, Nuñez-Toldra R, Brito L, Seong H, Becce M, Ouyang L, Grigsby CL, Higgins SG, Terracciano CM, Stevens MM, Stevens MM.   +12 more
europepmc   +1 more source