Results 31 to 40 of about 9,216,194 (230)

Clinical Relevance of Transforming Growth Factor-β1, Interleukin-6 and Haptoglobin for Prediction of Obesity Complications in Prepubertal Egyptian Children

Open Access Macedonian Journal of Medical Sciences, 2015
BACKGROUND: The rate of obesity is increasing throughout the world. Obesity in adults’ research is characterized by chronic inflammation, associated with type 2 Diabetes and cardiovascular risk. The degree to which these changes occur in childhood obesity is not fully defined.AIM: This study was designed to explore the relation between circulating ...
El-Alameey, Inas R., Fadl, Nevein N., Hameed, Enas R. Abdel, Sherif, Lobna S., Ahmed, Hanaa H.   +4 more
openaire   +3 more sources

Evaluation of TGF-β1 and MCP-1 expression and tubulointerstitial fibrosis in children with Henoch-Schönlein purpura nephritis and IgA nephropathy: A clinical correlation

Clinics
OBJECTIVES: Henoch-Schönlein purpura nephritis and immunoglobulin A nephropathy are two diseases with similar clinical presentations but very different prognoses.
Zhao Shuiai, Shen Huijun, Gu Weizhong, Liu Aimin, Mao Jianhua   +4 more
doaj   +1 more source

Type-1 Collagen differentially alters β-catenin accumulation in primary Dupuytren's Disease cord and adjacent palmar fascia cells

BMC Musculoskeletal Disorders, 2009
Background Dupuytren's Disease (DD) is a debilitating contractile fibrosis of the palmar fascia characterised by excess collagen deposition, contractile myofibroblast development, increased Transforming Growth Factor-β levels and β-catenin accumulation ...
Gan Bing, Wu Yan, Njarlangattil Anna, Vi Linda, O'Gorman David B   +4 more
doaj   +1 more source

The Role of <i>L. plantarum</i> as an Immunomodulator Secretion of <i>Transforming Growth Factor</i>-β1, <i>Transforming Growth Factor</i>-β3, and <i>Interferon</i>-α Macrophages and Dermal Fibroblasts

Asian Journal of Applied Sciences, 2017
This research aims to see the effect of L.plantarum in modulating the secretion of Transforming Growth Factor-TGFβ1, TGFβ3 macrophages and fibroblasts, Interferon-IFNα macrophages, and to analyze the possibility of L.plantarum potency in supporting the process of scarless wound healing.
Rita Shintawati, Sunarjati Sudigdoadi, Tita Husnitawati Madjid, Endang Sutedja   +3 more
openaire   +2 more sources

Additional file 1: of Partial epithelial-mesenchymal transition in keloid scars: regulation of keloid keratinocyte gene expression by transforming growth factor-β1

, 2016
Additional methods.
Hahn, Jennifer, McFarland, Kevin, Combs, Kelly, Supp, Dorothy   +3 more
openaire   +1 more source

Additional file 1: of P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression

, 2016
Supplementary information containing Table S1. presenting primer sequences used for real-time PCR, and Table S2. presenting the characterization of epithelial to myofibroblast/ myofibroblast-like cell transdifferentiation in 36 articles. (PDF 487 kb)
Li, Haisheng, Yao, Zhihui, He, Weifeng, Gao, Hongyan, Bai, Yang, Yang, Sisi, Zhang, Lu, Zhan, Rixing, Tan, Jianglin, Zhou, Junyi, Takata, Masao, Wu, Jun, Luo, Gaoxing   +12 more
openaire   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Marein alleviates myocardial fibrosis in diabetic mice [PDF]

Jichu yixue yu linchuang
Objective To study the effect of marein on myocardial fibrosis in diabetic mice. Methods Ten leptin receptor gene defective heterozygous (db/m) mice aged 5-6 weeks were selected as the control group and 30 diabetic mice with leptin receptor gene ...
TIAN Yating, ZHANG Fang, ZHANG Boxiang, LI Tian
doaj   +1 more source

Inhibitory Effects of Hepatocyte Growth Factor and Interleukin-6 on Transforming Growth Factor-β1 Mediated Vocal Fold Fibroblast-Myofibroblast Differentiation

, 2010
Objectives The role of myofibroblasts in vocal fold scarring has not been extensively studied, partly because of the lack of a robust in vitro model. The objective of this investigation was to develop and characterize a myofibroblast in vitro model that ...
Bimal Vyas, Xia Chen, Keiko Ishikawa, Susan L. Thibeault, Suzy Duflo   +4 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source