Results 11 to 20 of about 4,794 (208)

Transglycosylation products generated by Talaromyces amestolkiae GH3 β-glucosidases: effect of hydroxytyrosol, vanillin and its glucosides on breast cancer cells [PDF]

Microbial Cell Factories, 2019
Background Transglycosylation represents one of the most promising approaches for obtaining novel glycosides, and plant phenols and polyphenols are emerging as one of the best targets for creating new molecules with enhanced capacities.
Juan Antonio Méndez-Líter, Isabel Tundidor, Manuel Nieto-Domínguez, Beatriz Fernández de Toro, Andrés González Santana, Laura Isabel de Eugenio, Alicia Prieto, Juan Luis Asensio, Francisco Javier Cañada, Cristina Sánchez, María Jesús Martínez   +10 more
doaj   +2 more sources

Efficient Preparation of Homogenous Antibody Conjugates via Glycosite-Specific Transglycosylation Enabled by Readily Available Glycosyl Donors. [PDF]

Angew Chem Int Ed Engl
A streamlined platform for glycosite‐specific antibody conjugation is enabled by LacNAc‐derived cyclic acetal donors, which can be prepared in only two steps and used directly in single‐enzyme Endo S2‐mediated transglycosylation. The platform supports the broad construction of homogeneous gsADCs and gsDACs, with donor 7 producing glycoengineered ...
Cai D, Zhao Y, Lu G, Li C, Lao Y, Mudududdla R, Zhang J, Jia P, Huang P, Wu W, Nguyen TT, Huang X, Li L, Tang W.   +13 more
europepmc   +3 more sources

Studies on Lysozyme Catalyzed Transglycosylation [PDF]

Journal of the Faculty of Agriculture, Kyushu University, 1974
The lysozyme catalyzed transglycosylation with glycol chitin or related oligosaccharides as substrate and p-nitrophenyl β-glycoside of 2-acetamido-2-deoxy-D-glucopyranoside as acceptor was studied in order to obtain basic information which is expected to
Hayashi, Katsuya, Inohara, Yasuhiro, Taira, Kazutomo, Doi, Yasutaka, Funatsu, Masaru   +4 more
openaire   +2 more sources

Studies on Lysozyme Catalyzed Transglycosylation

Studies on Lysozyme Catalyzed Transglycosylation
The lysozyme catalyzed transglycosylation with glycol chitin or related oligosaccharides as substrate and p-nitrophenyl β-glycoside of 2-acetamido-2-deoxy-D-glucopyranoside as acceptor was studied in order to obtain basic information which is expected to be available for the elucidation of the mechanism of lysozyme catalyzed reaction.
Hayashi, Katsuya, 林, 勝哉, Funatsu, Masaru, Doi, Yasutaka, Inohara, Yasuhiro, Taira, Kazutomo, 船津, 勝   +6 more
openaire   +1 more source

Structural Insight into a Yeast Maltase—The BaAG2 from Blastobotrys adeninivorans with Transglycosylating Activity

Journal of Fungi, 2021
An early-diverged yeast, Blastobotrys (Arxula) adeninivorans (Ba), has biotechnological potential due to nutritional versatility, temperature tolerance, and production of technologically applicable enzymes. We have biochemically characterized from the Ba
Karin Ernits, Christian Kjeldsen, Karina Persson, Eliis Grigor, Tiina Alamäe, Triinu Visnapuu   +5 more
doaj   +1 more source

Generation of efficient mutants of endoglycosidase from Streptococcus pyogenes and their application in a novel one-pot transglycosylation reaction for antibody modification. [PDF]

PLoS ONE, 2018
The fine structures of Fc N-glycan modulate the biological functions and physicochemical properties of antibodies. By remodeling N-glycan to obtain a homogeneous glycoform or chemically modified glycan, antibody characteristics can be controlled or ...
Mitsuhiro Iwamoto, Yukiko Sekiguchi, Kensuke Nakamura, Yoshirou Kawaguchi, Takeshi Honda, Jun Hasegawa   +5 more
doaj   +1 more source

Green-Chemical Strategies for Production of Tailor-Made Chitooligosaccharides with Enhanced Biological Activities

Molecules, 2023
Chitooligosaccharides (COSs) are b-1,4-linked homo-oligosaccharides of N-acetylglucosamine (GlcNAc) or glucosamine (GlcN), and also include hetero-oligosaccharides composed of GlcNAc and GlcN.
Reeba Thomas, Tamo Fukamizo, Wipa Suginta   +2 more
doaj   +1 more source

Enzymatic transglycosylation for glycoconjugate synthesis [PDF]

Current Opinion in Chemical Biology, 2009
Remarkable advances have been made in recent years in exploiting the transglycosylation activity of glycosidases and glycosynthase mutants for oligosaccharide and glycoconjugate synthesis. New glycosynthases were generated from retaining glycosidases, inverting glycosidases, and those that proceed in a mechanism of substrate-assisted catalysis ...
Lai-Xi, Wang, Wei, Huang
openaire   +2 more sources

Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A. [PDF]

PLoS ONE, 2009
Endo-beta-N-acetylglucosaminidases (ENGases) are dual specificity enzymes with an ability to catalyze hydrolysis and transglycosylation reactions. Recently, these enzymes have become the focus of intense research because of their potential for synthesis ...
Jie Yin, Lei Li, Neil Shaw, Yang Li, Jing Katherine Song, Wenpeng Zhang, Chengfeng Xia, Rongguang Zhang, Andrzej Joachimiak, Hou-Cheng Zhang, Lai-Xi Wang, Zhi-Jie Liu, Peng Wang   +12 more
doaj   +1 more source

An Integrated Enzymatic Approach to Produce Pentyl Xylosides and Glucose/Xylose Laurate Esters From Wheat Bran

Frontiers in Bioengineering and Biotechnology, 2021
Alkyl glycosides and sugars esters are non-ionic surfactants of interest for various applications (cosmetics, food, detergency,…). In the present study, xylans and cellulose from wheat bran were enzymatically converted into pentyl xylosides and glucose ...
Chloé Jocquel, Murielle Muzard, Richard Plantier-Royon, Caroline Rémond   +3 more
doaj   +1 more source