Results 51 to 60 of about 773,655 (299)

Expression and function of transient receptor potential channels in the female bovine reproductive tract [PDF]

, 2016
© 2016 Elsevier Inc. The epithelium lining the oviduct is critical for early reproductive events, many of which are mediated via intracellular calcium ions.
Atkin, Stephen L., Ghavideldarestani, Maryam, Leese, Henry J., Sturmey, Roger G.   +3 more
core   +2 more sources

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development. [PDF]

, 2020
Developmental progression depends on temporally defined changes in gene expression mediated by transient exposure of lineage intermediates to signals in the progenitor niche.
Benner, Christopher W, Geusz, Ryan J, Harrington, Austin R, Jhala, Ulupi S, Matta, Ileana, Patel, Nisha A, Rosenfeld, Michael G, Sander, Maike, Shih, Hung-Ping, Vinckier, Nicholas K, Wang, Allen, Wang, Jianxun, Wang, Jinzhao, Wetton, Nichole, Wortham, Matthew   +14 more
core   +2 more sources

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

AGROBEST: an efficient Agrobacterium-mediated transient expression method for versatile gene function analyses in Arabidopsis seedlings [PDF]

, 2014
Background: Transient gene expression via Agrobacterium-mediated DNA transfer offers a simple and fast method to analyze transgene functions. Although Arabidopsis is the most-studied model plant with powerful genetic and genomic resources, achieving ...
Chen, Chao-Ying, Chiu, Wan-Ling, Lai, Erh-Min, Liu, Kun-Hsiang, Sheen, Jen, Wang, Yi-Chieh, Wu, Hung-Yi, Wu, Jing-Fen, Wu, Shu-Hsing   +8 more
core   +2 more sources

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Expression profiling of migrated and invaded breast cancer cells predicts early metastatic relapse and reveals Krüppel-like factor 9 as a potential suppressor of invasive growth in breast cancer [PDF]

, 2013
Cell motility and invasion initiate metastasis. However, only a subpopulation of cancer cells within a tumor will ultimately become invasive. Due to this stochastic and transient nature, in an experimental setting, migrating and invading cells need to be
Croes, Lieselot, De Wever, Olivier, De Wilde, Annemieke, Dirix, Luc, Lardon, Filip, LIMAME, RIDHA, Op de Beeck, Ken, Pauwels, Patrick, Peeters, Marc, Van Camp, Guy, Van Laere, Steven   +10 more
core   +3 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

RNAseq Analyses Identify Tumor Necrosis Factor-Mediated Inflammation as a Major Abnormality in ALS Spinal Cord [PDF]

, 2016
ALS is a rapidly progressive, devastating neurodegenerative illness of adults that produces disabling weakness and spasticity arising from death of lower and upper motor neurons.
A Al-Chalabi, A Chesi, A Dobin, A Hirano, A Kratz, A McKenna, A Saito, A Zhou, AB van Spriel, AE Renton, AM Bolger, AT Kwon, B Hoesel, B Ikiz, B Tian, B Zhang, C Cereda, C Figueroa-Romero, C Trapnell, Cedric Raoul, CG Saris, CM Higgins, CY Jin, D Brustolim, D Kim, D Kim, D Liu, D Nagy, D Schiffer, David G. Brohawn, DJ Park, ED Hall, EW Stommel, GA Van der Auwera, GN Babu, H Jeong, H Li, H Tanaka, IM Chiu, IR Holtman, J Ganesalingam, J Kong, J Satoh, James P. Bennett, JL Elliott, JS Henkel, JS Henkel, K Hattermann, K Hensley, KE Lewis, KM Mohler, L Probert, Laura C. O’Brien, LB Fanning, LC O'Brien, LJ Kogelman, M Damiano, M Hausmann, M Maschietto, M Mattiazzi, M Poloni, M Prudencio, MA DePristo, MD Robinson, ME Alexianu, ME Rusiniak, MG Hinds, MI Love, MJ Landrum, MR Turner, MW Amoroso, O Abel, O Hardiman, O Micheau, P Corcia, P Langfelder, PB Verghese, PD Stenson, PG Engstrom, PK Andrus, PR Heath, RJ Ferrante, S Abel, S Anders, S Byrne, S Hagl, S Horvath, S Khan, S Sasaki, S Sasaki, SL Carter, SN Dowey, SS Han, T Yoshihara, W Zhao, Y Chang, Y Ma, YJ Surh, Z Wang, ZH Zhang   +99 more
core   +10 more sources

Carbon-nanotube for Transient Expression in Rice Calli

Hayati Journal of Biosciences, 2022
Transient gene expression is an important technique in gene functional analysis, protein production and in plants. However, traditional transient expression methods using Agrobacterium are time-consuming with low efficiency.
Paphawarin Pinyokham, Kamolwan Khianchaikhan, Pongsakorn Sunvittayakul, Supachai Vuttipongchaikij, Piyama Tasanasuwan, Chatchawan Jantasuriyarat   +5 more
doaj   +1 more source

Developmental regulation of expression of the lactate dehydrogenase (LDH) multigene family during mouse spermatogenesis [PDF]

, 1990
Expression of the Lactate Dehydrogenase (LDH) genes during various stages of spermatogenesis was studied by using a combination of Northern blot analyses and in situ hybridization techniques.
Bellvé, Anthony, Del Mazo, Jesus, Eversole, Pam, Hiraoka, Yukihiro, Li, Steven S. L., Simon, Melvin, Thomas, Kelwyn   +6 more
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