Results 41 to 50 of about 243,028 (200)
TRPV3-ANO1 interaction positively regulates wound healing in keratinocytes
Communications Biology, 2023 The chloride channel anoctamin1, upon activation by calcium influx through transient receptor potential vanilloid 3, mediates chloride influx and enhances wound healing in keratinocytes.
Yu Yamanoi +5 more
doaj +1 more source
Frontiers in Endocrinology, 2022 The transient receptor potential vanilloid (TRPV) ion channel family is involved in multiple sensory and physiological functions including thermosensing and temperature-dependent neuroendocrine regulation.
Marina Morini +5 more
doaj +1 more source
Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways. [PDF]
, 2016 Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or infection, evokes a complex cellular response (inflammation) that is associated with painful hyperalgesic states.
Guan, Zhonghui +2 more
core +2 more sources
The neurochemistry and morphology of functionally identified corneal polymodal nociceptors and cold thermoreceptors. [PDF]
PLoS ONE, 2018 It is generally believed that the unencapsulated sensory nerve terminals of modality specific C- and Aδ-neurons lack structural specialization. Here we determined the morphology of functionally defined polymodal receptors and cold thermoreceptors in the ...
Abdulhakeem S Alamri +3 more
doaj +1 more source
Structural insights on TRPV5 gating by endogenous modulators. [PDF]
, 2018 TRPV5 is a transient receptor potential channel involved in calcium reabsorption. Here we investigate the interaction of two endogenous modulators with TRPV5.
Carnevale, Vincenzo +13 more
core +3 more sources
Drug Design, Development and Therapy, 2020 Jin Yu, Caifeng Zhu, Jiazhen Yin, Dongrong Yu, Feng Wan, Xuanli Tang, Xue Jiang Department of Nephrology, Guangxing Hospital Affiliated to ZheJiang Chinese Medical University (Key Laboratory of Zhejiang Province, Management of Kidney Disease), Hangzhou ...
Yu J +6 more
doaj
Insulin Increases Expression of TRPC6 Channels in Podocytes by a Calcineurin-Dependent Pathway
Cellular Physiology and Biochemistry, 2016 Background/Aims: Insulin signaling to podocytes is relevant for the function of the glomerulus. Now, we tested the hypothesis that insulin increases the surface expression of canonical transient receptor potential canonical type 6 (TRPC6) channels in ...
Shengqiang Xia +4 more
doaj +1 more source
Cholesterol Stimulates the Transient Receptor Potential Melastatin 4 Channel in mpkCCDc14 Cells
Frontiers in Pharmacology, 2021 We have shown that cholesterol regulates the activity of ion channels in mouse cortical collecting duct (CCD) mpkCCDc14 cells and that the transient receptor potential melastatin 4 (TRPM4) channel is expressed in these cells.
Yong-Xu Cai +14 more
doaj +1 more source
PKC-dependent Phosphorylation of the H1 Histamine Receptor Modulates TRPC6 Activity [PDF]
, 2014 Transient receptor potential canonical 6 (TRPC6) is a cation selective, DAG-regulated, Ca2+-permeable channel activated by the agonists of Gq-protein-coupled heptahelical receptors.
Chen, Xingjuan +7 more
core +2 more sources
Molecular Sensors and Modulators of Thermoreception [PDF]
, 2015 Peer ...
Zhang, Xuming
core +1 more source