Results 81 to 90 of about 243,028 (200)

Aldosterone signaling through transient receptor potential melastatin 7 cation channel (TRPM7) and its α-kinase domain [PDF]

, 2013
We demonstrated a role for the Mg2 + transporter TRPM7, a bifunctional protein with channel and α-kinase domains, in aldosterone signaling. Molecular mechanisms underlying this are elusive.
Yogi, A., Callera, G.E., O'Connor, S., Antunes, T.T., Valinsky, W., Miquel, P., Montezano, A.C.I., Perraud, A.-L., Schmitz, C., Shrier, A., Touyz, R.M.   +10 more
core   +2 more sources

Pan-cancer analyses reveal the genetic and pharmacogenomic landscape of transient receptor potential channels [PDF]

, 2022
Tao Pan, Yueying Gao, Gang Xu, Ping Zhou, Si Li, Jing Guo, Haozhe Zou, Qi Xu, Xiaoyan Huang, Juan Xu, Yongsheng Li   +10 more
openalex   +1 more source

The Mitochondrial Ca(2+) Uniporter: Structure, Function, and Pharmacology. [PDF]

, 2017
Mitochondrial Ca(2+) uptake is crucial for an array of cellular functions while an imbalance can elicit cell death. In this chapter, we briefly reviewed the various modes of mitochondrial Ca(2+) uptake and our current understanding of mitochondrial Ca(2+)
A Quintana, A Raffaello, A Rasola, A Tosatto, A Varadi, AA Rowland, AI Tarasov, AN Antony, AR Marks, B Chance, B Glancy, B Moreau, C Giorgi, C Petrungaro, CC Mendes, CD Lobaton, CV Logan, CV Nicchitta, D Chaudhuri, D Chaudhuri, D De Stefani, D Jiang, D Lewis-Smith, D Tomar, D Vecellio Reane, DA Cox, DD Hall, DG Nicholls, DJ Pagliarini, E Carafoli, E Carafoli, E Kovacs-Bogdan, E Murphy, E Noack, E Rapizzi, F Fieni, F Fieni, F Perocchi, FD Vasington, G Bathori, G Beutner, G Beutner, G Csordas, G Csordas, G Csordas, G Csordas, G Csordas, G Csordas, G Csordas, G Czirjak, G Giannini, G Hajnoczky, G Hajnoczky, G Huang, G Michels, G Munch, G Szabadkai, G Szalai, G Szanda, G Szanda, GA Rutter, GC Sparagna, GD Schellenberg, GL Becker, H Vais, HF Deluca, I Bogeski, I Drago, I Zimanyi, J Matesanz-Isabel, J Nakai, J O-Uchi, J O-Uchi, J O-Uchi, J Qiu, J Santo-Domingo, J Schwartz, JD Martell, JG McCormack, JL Harrington, JM Baughman, JQ Kwong, JS Marchant, JT Lanner, JW Putney Jr, K Mallilankaraman, K Mallilankaraman, K Oxenoid, KJ Kamer, KM Holmstrom, L Buntinas, L Hymel, L Mela, L Wang, LH Jeyakumar, LK Seidlmayer, LS Jouaville, M Boerries, M Crompton, M Crompton, M Giacomello, M Giacomello, M Hoth, M Hoth, M Montero, M Montero, M Murgia, M Patron, M Plovanich, M Salvi, M Sastrasinh, MA Matlib, MF Tsai, MK Park, ML Joiner, ML Joiner, ML Litsky, ML Olson, MR Alam, MR Duchen, N MacQuaide, NE Hoffman, NJ Dolman, P Bernardi, P Koncz, P Pinton, PJ Doonan, PS Brookes, R Amann, R Jakob, R Malli, R Malli, R Perez-Campo, R Rizzuto, R Rizzuto, R Rizzuto, R Rizzuto, RM Denton, RM Denton, RM Denton, RS Sohal, S Feng, S Fuente de la, S Grimm, S Marchi, S Shanmughapriya, S Xu, SA Thayer, SS Lam, SY Ryu, T Pozzan, T Rharass, T Yamamoto, TE Gunter, TE Gunter, TE Gunter, TS Luongo, V Hung, V Paupe, VK Sharma, W Tan, WL Ying, X Pan, X Quan, Y Kirichok, Y Lee, Y Sancak, Y Wu   +167 more
core   +2 more sources

Dominant mutations in the cation channel gene transient receptor potential vanilloid 4 cause an unusual spectrum of neuropathies [PDF]

, 2017
Hereditary neuropathies form a heterogeneous group of disorders for which over 40 causal genes have been identified to date. Recently, dominant mutations in the transient receptor potential vanilloid 4 gene were found to be associated with three distinct
Auer-Grumbach, Michaela, Baets, Jonathan, Barisic, Nina, Berciano, José, Boltshauser, Eugen, Crosby, Andrew H., Fischbeck, Kenneth H., Garcia, Antonio, Gaudet, Rachelle, Hilton-Jones, David, Houlden, Henry, Jonghe, Peter De, Jordanova, Albena, Landouré, Guida, Lopez-Laso, Eduardo, Ludlow, Christy L., McEntagart, Meriel, Merlini, Luciano, Reilly, Mary M., Shaw, Christopher E., Sumner, Charlotte J., Timmerman, Vincent, Zimoń, Magdalena   +22 more
core  

Selective Gαi Subunits as Novel Direct Activators of Transient Receptor Potential Canonical (TRPC)4 and TRPC5 Channels [PDF]

, 2012
Jae-Pyo Jeon, Chansik Hong, Eun‐Jung Park, Ju‐Hong Jeon, Nam‐Hyuk Cho, In Gyu Kim, Han Choe, Shmuel Muallem, Hyun Jin Kim, Insuk So   +9 more
openalex   +1 more source

Molecular mechanism of TRPV2 channel modulation by cannabidiol

eLife, 2019
Transient receptor potential vanilloid 2 (TRPV2) plays a critical role in neuronal development, cardiac function, immunity, and cancer. Cannabidiol (CBD), the non-psychotropic therapeutically active ingredient of Cannabis sativa, is an activator of TRPV2
Ruth A Pumroy, Amrita Samanta, Yuhang Liu, Taylor ET Hughes, Siyuan Zhao, Yevgen Yudin, Tibor Rohacs, Seungil Han, Vera Y Moiseenkova-Bell   +8 more
doaj   +1 more source

Multimodal roles of transient receptor potential channel activation in inducing pathological tissue scarification. [PDF]

Front Immunol, 2023
Zheng Y, Huang Q, Zhang Y, Geng L, Wang W, Zhang H, He X, Li Q.   +7 more
europepmc   +1 more source

Receptor for Activated C Kinase 1 (RACK1) Inhibits Function of Transient Receptor Potential (TRP)-type Channel Pkd2L1 through Physical Interaction [PDF]

, 2011
Jungwoo Yang, Qian Wang, Wang Zheng, Jagdeep Tuli, Qiang Li, Yuliang Wu, Shaimaa Hussein, Xiao‐Qing Dai, Shiva Shafiei, Xiao-Gai Li, Patrick Y. Shen, Jiancheng Tu, Xing‐Zhen Chen   +12 more
openalex   +1 more source

Baicalein and <i>Salvia officinalis</i> Extract Upregulate Transglutaminase 1 mRNA Expression via the Activation of Transient Receptor Potential Channel V4

, 2022
Akihiro Aioi, Ryuta Muromoto, Tadashi Matsuda   +2 more
openalex   +2 more sources

TRPML1 gating modulation by allosteric mutations and lipids

eLife
Transient Receptor Potential Mucolipin 1 (TRPML1) is a lysosomal cation channel whose loss-of-function mutations directly cause the lysosomal storage disorder mucolipidosis type IV (MLIV).
Ninghai Gan, Yan Han, Weizhong Zeng, Youxing Jiang   +3 more
doaj   +1 more source