Catechol estrogens stimulate insulin secretion in pancreatic β-cells via activation of the transient receptor potential A1 (TRPA1) channel [PDF]
, 2019 Estrogen hormones play an important role in controlling glucose homeostasis and pancreatic β-cell function. Despite the significance of estrogen hormones for regulation of glucose metabolism, little is known about the roles of endogenous estrogen ...
Cabrera, Over +7 more
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Transient Receptor Potential (TRP) Channels in Health and Disease
Cells, 2019 Almost 25 years ago, the first mammalian transient receptor potential (TRP) channel, now named TRPC1, was cloned and published (reviewed in [...]
Alexander Dietrich
doaj +1 more source
Dependence of NMDA/GSK-3β Mediated Metaplasticity on TRPM2 Channels at Hippocampal CA3-CA1 Synapses [PDF]
, 2011 Transient receptor potential melastatin 2 (TRPM2) is a calcium permeable non-selective cation channel that functions as a sensor of cellular redox status. Highly expressed within the CNS, we have previously demonstrated the functional expression of these
Yu-Feng Xie +6 more
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Transient receptor potential (TRP) gene superfamily encoding cation channels
Human Genomics, 2011 Transient receptor potential (TRP) non-selective cation channels constitute a superfamily, which contains 28 different genes. In mammals, this superfamily is divided into six subfamilies based on differences in amino acid sequence homology between the ...
Pan Zan, Yang Hua, Reinach Peter S
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Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior [PDF]
, 2006 The S100 family protein p11 (S100A10, annexin 2 light chain) is involved in the trafficking of the voltage-gated sodium channel Na(V)1.8, TWIK-related acid-sensitive K+ channel (TASK-1), the ligand-gated ion channels acid-sensing ion channel 1a (ASIC1a ...
Baker, MD +8 more
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TRPC1 channels underlie stretch-modulated sarcoplasmic reticulum calcium leak in cardiomyocytes
Frontiers in Physiology, 2022 Transient receptor potential canonical 1 (TRPC1) channels are Ca2+-permeable ion channels expressed in cardiomyocytes. An involvement of TRPC1 channels in cardiac diseases is widely established.
Molly E. Streiff +8 more
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, 2018 Background: The spread of tumors through neural routes is common in several types of cancer in which patients suffer from a moderate-to-severe neuropathy, neural damage and a distorted quality of life.
Elsadek, Bakheet, Maqboul, Ahmad
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Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held Synapse [PDF]
, 2017 Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases. We found that these channels can be activated in neurons of the medial nucleus of the trapezoid body (MNTB) of the auditory system in ...
Di Guilmi, Mariano Nicolás +3 more
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Erythropoietin Increases Expression and Function of Transient Receptor Potential Canonical 5 Channels [PDF]
, 2011 Hypertension is a common complication in hemodialysis patients during erythropoietin (EPO) treatment. The underlying mechanisms of EPO-induced hypertension still remain to be determined. Increased transient receptor potential canonical (TRPC)
Friis, Ulla G +7 more
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Transient Receptor Potential Channels and Metabolism.
Molecules and cells, 2019 Transient receptor potential (TRP) channels are nonselective cationic channels, conserved among flies to humans. Most TRP channels have well known functions in chemosensation, thermosensation, and mechanosensation. In addition to being sensing environmental changes, many TRP channels are also internal sensors that help maintain homeostasis.
Dhakal, Subash, Lee, Youngseok
openaire +2 more sources