Canonical transient receptor potential channels and hypothalamic control of homeostatic functions. [PDF]
J NeuroendocrinolKelly MJ, Wagner EJ.
europepmc +3 more sources
Transient receptor potential ion channels control thermoregulatory behaviour in reptiles. [PDF]
PLoS ONE, 2007 Biological functions are governed by thermodynamics, and animals regulate their body temperature to optimise cellular performance and to avoid harmful extremes.
Frank Seebacher, Shauna A Murray
doaj +1 more source
Structure of the full-length TRPV2 channel by cryo-EM. [PDF]
, 2016 Transient receptor potential (TRP) proteins form a superfamily Ca(2+)-permeable cation channels regulated by a range of chemical and physical stimuli. Structural analysis of a 'minimal' TRP vanilloid subtype 1 (TRPV1) elucidated a mechanism of channel ...
Cohen, Matthew R +6 more
core +2 more sources
Ultrasonic neuromodulation mediated by mechanosensitive ion channels: current and future
Frontiers in Neuroscience, 2023 Ultrasound neuromodulation technology is a promising neuromodulation approach, with the advantages of noninvasiveness, high-resolution, deep penetration and good targeting, which aid in circumventing the side effects of drugs and invasive therapeutic ...
Mengyao Song +9 more
doaj +1 more source
Distance constraints on activation of TRPV4 channels by AKAP150-bound PKCĪ± in arterial myocytes. [PDF]
, 2017 TRPV4 (transient receptor potential vanilloid 4) channels are Ca2+-permeable channels that play a key role in regulating vascular tone. In arterial myocytes, opening of TRPV4 channels creates local increases in Ca2+ influx, detectable optically as "TRPV4
Moreno, Claudia M +6 more
core +3 more sources
TRPing to the Point of Clarity: Understanding the Function of the Complex TRPV4 Ion Channel
Cells, 2021 The transient receptor potential vanilloid 4 channel (TRPV4) belongs to the mammalian TRP superfamily of cation channels. TRPV4 is ubiquitously expressed, activated by a disparate array of stimuli, interacts with a multitude of proteins, and is modulated
Trine L. Toft-Bertelsen, Nanna MacAulay
doaj +1 more source
Insights into Activation Mechanisms of Store-Operated TRPC1 Channels in Vascular Smooth Muscle. [PDF]
, 2020 In vascular smooth muscle cells (VMSCs), the stimulation of store-operated channels (SOCs) mediate Ca2+ influx pathways which regulate important cellular functions including contraction, proliferation, migration, and growth that are associated with the ...
Albert, AP +3 more
core +1 more source
Cellular functions of Transient Receptor Potential channels [PDF]
The International Journal of Biochemistry & Cell Biology, 2010 Transient Receptor Potential channels are polymodal cellular sensors involved in a wide variety of cellular processes, mainly by increasing cellular Ca(2+). In this review we focus on the roles of these channels in: (i) cell death (ii) proliferation and differentiation and (iii) transmitter release.
Daniela, Dadon, Baruch, Minke
openaire +2 more sources
Involvement of Neural Transient Receptor Potential Channels in Peripheral Inflammation
Frontiers in Immunology, 2020 Transient receptor potential (TRP) channels are a superfamily of non-selective cation channels that act as polymodal sensors in many tissues throughout mammalian organisms.
Harold A. Silverman +11 more
doaj +1 more source
Functional expression of TRPV4 channels in human collecting duct cells: implications for secondary hypertension in diabetic nephropathy [PDF]
, 2012 Background. The Vanilloid subfamily of transient receptor potential (TRPV) ion channels has been widely implicated in detecting osmotic and mechanical stress.
Bland, Rosemary +2 more
core +3 more sources