Results 31 to 40 of about 202,065 (342)

Dysfunction of transient receptor potential ion channels as an important pathophysiological mechanism in asthma

open access: yesRussian Open Medical Journal, 2020
Asthma is a chronic heterogeneous disease characterized by chronic inflammation and bronchial hyperreactivity. Neurogenic inflammation is one of the important causes of hyperreactivity.
Oxana Y. Kytikova   +4 more
doaj   +1 more source

Vanilloid Transient Receptor Potential Cation Channels: An Overview [PDF]

open access: bronzeCurrent Pharmaceutical Design, 2008
The mammalian branch of the Transient Receptor Potential (TRP) superfamily of cation channels consists of 28 members. They can be subdivided in six main subfamilies: the TRPC ('Canonical'), TRPV ('Vanilloid'), TRPM ('Melastatin'), TRPP ('Polycystin'), TRPML ('Mucolipin') and the TRPA ('Ankyrin') group.
Bernd Nilius   +2 more
openalex   +5 more sources

Modulation of Calcium Transients in Cardiomyocytes by Transient Receptor Potential Canonical 6 Channels

open access: yesFrontiers in Physiology, 2020
Transient receptor potential canonical 6 (TRPC6) channels are non-selective cation channels that are thought to underlie mechano-modulation of calcium signaling in cardiomyocytes.
Azmi A. Ahmad   +6 more
doaj   +1 more source

Transient receptor potential ion channels and cerebral stroke

open access: yesBrain and Behavior, 2023
Methods The databases Pubmed, and the National Library of Medicine were searched for literature. All papers on celebral stroke and transient receptor potential ion channels were considered.
Qin'yi Xu   +4 more
doaj   +1 more source

Transient Receptor Potential (TRP) Channels in Haematological Malignancies: An Update

open access: yesBiomolecules, 2021
Transient receptor potential (TRP) channels are improving their importance in different cancers, becoming suitable as promising candidates for precision medicine.
Federica Maggi   +7 more
doaj   +1 more source

Transient receptor potential channel TRPV4 mediates TGF-β1-induced differentiation of human ventricular fibroblasts

open access: yesCardiology Journal, 2020
BACKGROUND: Cardiac fibroblasts (CFs) are principal extracellular matrix-producing cells. In response to injury, CFs transdifferentiate into myofibroblasts. Intracellular calcium (Ca2+) signaling, involved in fibroblast proliferation and differentiation,
Min-Soo Ahn   +12 more
doaj   +1 more source

Temperature activated transient receptor potential ion channels from Antarctic fishes

open access: yesOpen Biology, 2023
Antarctic notothenioid fishes (cryonotothenioids) live in waters that range between −1.86°C and an extreme maximum +4°C. Evidence suggests these fish sense temperature peripherally, but the molecular mechanism of temperature sensation in unknown ...
Julia M. York
doaj   +1 more source

TRPV4-A Missing Link Between Mechanosensation and Immunity [PDF]

open access: yes, 2020
Transient receptor potential vanilloid-type 4 (TRPV4) cation channel is widely expressed in all tissues as well as in immune cells and its function as mechanosensitive Ca2+ channel seems to be conserved throughout all mammalian species. Of late, emerging
Kuebler, Wolfgang M., Michalick, Laura
core   +1 more source

Transient Receptor Potential Canonical (TRPC) Channels: Then and Now

open access: yesCells, 2020
Twenty-five years ago, the first mammalian Transient Receptor Potential Canonical (TRPC) channel was cloned, opening the vast horizon of the TRPC field. Today, we know that there are seven TRPC channels (TRPC1–7).
Xingjuan Chen   +4 more
doaj   +1 more source

Expression and function of transient receptor potential channels in the female bovine reproductive tract [PDF]

open access: yes, 2016
© 2016 Elsevier Inc. The epithelium lining the oviduct is critical for early reproductive events, many of which are mediated via intracellular calcium ions.
Atkin, Stephen L.   +3 more
core   +2 more sources

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