Ultrasonic neuromodulation mediated by mechanosensitive ion channels: current and future
Frontiers in Neuroscience, 2023 Ultrasound neuromodulation technology is a promising neuromodulation approach, with the advantages of noninvasiveness, high-resolution, deep penetration and good targeting, which aid in circumventing the side effects of drugs and invasive therapeutic ...
Mengyao Song +9 more
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Transient receptor potential channels in Alzheimer's disease
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007 Cognitive impairment and emotional disturbances in Alzheimer's disease (AD) result from the degeneration of synapses and neuronal death in the limbic system and associated regions of the cerebral cortex. An alteration in the proteolytic processing of the amyloid precursor protein (APP) results in increased production and accumulation of amyloid beta ...
Yamamoto, Shinichiro +4 more
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TRPing to the Point of Clarity: Understanding the Function of the Complex TRPV4 Ion Channel
Cells, 2021 The transient receptor potential vanilloid 4 channel (TRPV4) belongs to the mammalian TRP superfamily of cation channels. TRPV4 is ubiquitously expressed, activated by a disparate array of stimuli, interacts with a multitude of proteins, and is modulated
Trine L. Toft-Bertelsen, Nanna MacAulay
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Inhibition of diacylglycerol–sensitive TRPC channels by synthetic and natural steroids [PDF]
, 2012 TRPC channels are a family of nonselective cation channels that regulate ion homeostasis and intracellular Ca2+ signaling in numerous cell types. Important physiological functions such as vasoregulation, neuronal growth, and pheromone recognition have ...
Kleemann, Heinz-Werner +35 more
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Involvement of Neural Transient Receptor Potential Channels in Peripheral Inflammation
Frontiers in Immunology, 2020 Transient receptor potential (TRP) channels are a superfamily of non-selective cation channels that act as polymodal sensors in many tissues throughout mammalian organisms.
Harold A. Silverman +11 more
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The role of transient receptor potential channels in joint diseases [PDF]
European Cells & Materials, 2017 ransient receptor potential channels (TRP channels) are cation selective transmembrane receptors with diverse structures, activation mechanisms and physiological functions.
O Krupkova, J Zvick, K Wuertz-Kozak
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Functional expression of TRPV4 channels in human collecting duct cells : implications for secondary hypertension in diabetic nephropathy [PDF]
, 2012 Background. The Vanilloid subfamily of transient receptor potential (TRPV) ion channels has been widely implicated in detecting osmotic and mechanical stress.
Hills, Claire E. +2 more
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Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts
Pharmaceuticals, 2017 2017 marks the 20th anniversary of the molecular cloning by David Julius and colleagues (1997) of the long sought-after capsaicin receptor, now known as TRPV1 (Transient Receptor Potential Vanilloid 1) [1].
Susan Huang, Arpad Szallasi
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Biomedicines, 2022 Background: Atrial fibroblasts activation causes atrial fibrosis, which is one major pathophysiological contributor to atrial fibrillation (AF) genesis.
Yuan Hung +6 more
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Anàlisi genètica i funcional de la migranya hemiplègica i la migranya comuna [PDF]
, 2011 [cat] Aquesta tesi es centra en la genètica de la migranya. La migranya comuna és un trastorn neurològic caracteritzat per episodis recurrents de mal de cap.
Carreño, Oriel
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