Results 11 to 20 of about 10,656,275 (241)
Vanilloid transient receptor potential cation channels: An overview [PDF]
Current Pharmaceutical Design, 2008 The mammalian branch of the Transient Receptor Potential ( TRP) superfamily of cation channels consists of 28 members. They can be subdivided in six main subfamilies: the TRPC ('Canonical'), TRPV ('Vanilloid'), TRPM ('Melastatin'), TRPP ('Polycystin ...
Vennekens, Rudi +2 more
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Materials Today Advances, 2023 Reactive oxygen species (ROS) play an important role in regulating various physiological functions by activating specific ion channels to mediate cell growth, proliferation, regeneration, and apoptosis.
Boying Li +7 more
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Role of Known Transient Receptor Potential Vanilloid Channels in Modulating Cardiac Mechanobiology
Frontiers in Physiology, 2021 The transient receptor potential (TRP) channels have been described in almost every mammalian cell type. Several members of the Vanilloid (TRPV) subtype have been found to play important roles in modulating cardiac structure and function through Ca2 ...
Michael Miller +6 more
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Transient Receptor Potential Cation Channels in Disease [PDF]
Physiological Reviews, 2007 The transient receptor potential (TRP) superfamily consists of a large number of cation channels that are mostly permeable to both monovalent and divalent cations. The 28 mammalian TRP channels can be subdivided into six main subfamilies: the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystin), TRPML (mucolipin), and the TRPA ...
Nilius, Bernd +3 more
openaire +2 more sources
Russian Open Medical Journal, 2020 Asthma is a chronic heterogeneous disease characterized by chronic inflammation and bronchial hyperreactivity. Neurogenic inflammation is one of the important causes of hyperreactivity.
Oxana Y. Kytikova +4 more
doaj +1 more source
Frontiers in Physiology, 2020 Transient receptor potential canonical 6 (TRPC6) channels are non-selective cation channels that are thought to underlie mechano-modulation of calcium signaling in cardiomyocytes.
Azmi A. Ahmad +6 more
doaj +1 more source
Transient Receptor Potential (TRP) Channels [PDF]
, 2018 Transient Receptor Potential (TRP) channels are evolutionarily conserved integral membrane proteins. The mammalian TRP superfamily of ion channels consists of 28 cation permeable channels that are grouped into six subfamilies based on sequence homology (Fig. 6.1).
Amrita, Samanta +2 more
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Transient Receptor Potential (TRP) Channels in Haematological Malignancies: An Update
Biomolecules, 2021 Transient receptor potential (TRP) channels are improving their importance in different cancers, becoming suitable as promising candidates for precision medicine.
Federica Maggi +7 more
doaj +1 more source
Cardiology Journal, 2020 BACKGROUND: Cardiac fibroblasts (CFs) are principal extracellular matrix-producing cells. In response to injury, CFs transdifferentiate into myofibroblasts. Intracellular calcium (Ca2+) signaling, involved in fibroblast proliferation and differentiation,
Min-Soo Ahn +12 more
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Transient Receptor Potential Channels and Calcium Signaling [PDF]
Cold Spring Harbor Perspectives in Biology, 2019 Transient receptor potential (TRP) cation channels play diverse roles in cellular Ca2+ signaling. First, as Ca2+-permeable channels that respond to a variety of stimuli, TRP channels can directly initiate cellular Ca2+ signals. Second, as nonselective cation channels, TRP channel activation leads to membrane depolarization, influencing Ca2+ influx via ...
Vangeel, Laura, Voets, Thomas
openaire +3 more sources