Transient Receptor Potential Channels in Cardiovascular and Renal Diseases [PDF]
Cells, 2022 Transient receptor potential (TRP) channels belong to a superfamily of integral membrane proteins with diverse functions in sensory perception and cellular physiology [...]
Shuangtao Ma, Michael X. Zhu
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Transient Receptor Potential Channels and Inflammatory Bowel Disease [PDF]
Frontiers in Immunology, 2020 The transient receptor potential (TRP) cation channels are present in abundance across the gastrointestinal (GI) tract, serving as detectors for a variety of stimuli and secondary transducers for G-protein coupled receptors.
Yiding Chen +8 more
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Transient receptor potential channels meet phosphoinositides [PDF]
The EMBO Journal, 2008 Transient receptor potential (TRP) cation channels are unique cellular sensors that are involved in multiple cellular functions, ranging from transduction of sensory signals to the regulation of Ca(2+) and Mg(2+) homoeostasis. Malfunctioning of TRP channels is now recognized as the cause of several hereditary and acquired human diseases. At the time of
Nilius, Bernd +2 more
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Transient Receptor Potential Cation Channels in Disease [PDF]
Physiological Reviews, 2007 The transient receptor potential (TRP) superfamily consists of a large number of cation channels that are mostly permeable to both monovalent and divalent cations. The 28 mammalian TRP channels can be subdivided into six main subfamilies: the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystin), TRPML (mucolipin), and the TRPA ...
Nilius, Bernd +3 more
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Transient Receptor Potential Channels and Botulinum Neurotoxins in Chronic Pain [PDF]
Frontiers in Molecular Neuroscience, 2021 Pain afflicts more than 1.5 billion people worldwide, with hundreds of millions suffering from unrelieved chronic pain. Despite widespread recognition of the importance of developing better interventions for the relief of chronic pain, little is known ...
Eun Jin Go +4 more
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Transient receptor potential channels’ genes forecast cervical cancer outcomes and illuminate its impact on tumor cells [PDF]
Frontiers in GeneticsIntroduction: In recent years, there has been a strong association between transient receptor potential (TRP) channels and the development of various malignancies, drug resistance, and resistance to radiotherapy.
Shan Jiang +10 more
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Expression and functions of transient receptor potential channels in liver diseases [PDF]
Acta Pharmaceutica Sinica B, 2023 Liver diseases constitute a major healthcare burden globally, including acute hepatic injury resulted from acetaminophen overdose, ischemia–reperfusion or hepatotropic viral infection and chronic hepatitis, alcoholic liver disease (ALD), non-alcoholic ...
Wenhui Wang +6 more
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Druggable Lipid Binding Sites in Pentameric Ligand-Gated Ion Channels and Transient Receptor Potential Channels [PDF]
Frontiers in Physiology, 2022 Lipids modulate the function of many ion channels, possibly through direct lipid-protein interactions. The recent outpouring of ion channel structures by cryo-EM has revealed many lipid binding sites.
Wayland W. L. Cheng +2 more
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Editorial: Transient receptor potential channels (TRP): signal transduction [PDF]
Frontiers in Molecular Biosciences, 2023 Alexander Dietrich +3 more
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Functional expression of transient receptor potential channels in human preadipocytes [PDF]
, 2011 published_or_final_versionThe 16th Medical Resarch Conference (MRC), The University of Hong Kong, Hong Kong, China, 22 January 2011. In Hong Kong Medical Journal, 2011, v. 17, suppl. 1, p.
Hui Che, Gang Li
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