Transient Receptor Potential Channels in the Vasculature
Physiological Reviews, 2015 The mammalian genome encodes 28 distinct members of the transient receptor potential (TRP) superfamily of cation channels, which exhibit varying degrees of selectivity for different ionic species. Multiple TRP channels are present in all cells and are involved in diverse aspects of cellular function, including sensory perception and signal transduction.
Scott, Earley, Joseph E, Brayden
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Permeation and Rectification in Canonical Transient Receptor Potential-6 (TRPC6) Channels [PDF]
Frontiers in Physiology, 2018 Transient receptor potential-6 channels are widely expressed cation channels that play a role in regulating Ca2+ dynamics, especially during G protein-coupled receptor signaling.
Stuart E. Dryer +2 more
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Differing endometrial expression of calcium modulating transient receptor potential channels [PDF]
Journal of Translational Medicine, 2021 Maryam Ghavideldarestani +2 more
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Materials Today Advances, 2023 Reactive oxygen species (ROS) play an important role in regulating various physiological functions by activating specific ion channels to mediate cell growth, proliferation, regeneration, and apoptosis.
Boying Li +7 more
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Role of Known Transient Receptor Potential Vanilloid Channels in Modulating Cardiac Mechanobiology
Frontiers in Physiology, 2021 The transient receptor potential (TRP) channels have been described in almost every mammalian cell type. Several members of the Vanilloid (TRPV) subtype have been found to play important roles in modulating cardiac structure and function through Ca2 ...
Michael Miller +6 more
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Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries [PDF]
, 2014 Transient receptor potential canonical type 3 (TRPC3) channels are non-selective cation channels and regulate intracellular Ca2+ concentration. We examined the role of TRPC3 channels in agonist-, membrane depolarization (high K+)-, and mechanical ...
Abramowitz, Joel +6 more
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Transient Receptor Potential (TRP) Channels [PDF]
, 2018 Transient Receptor Potential (TRP) channels are evolutionarily conserved integral membrane proteins. The mammalian TRP superfamily of ion channels consists of 28 cation permeable channels that are grouped into six subfamilies based on sequence homology (Fig. 6.1).
Amrita, Samanta +2 more
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Thermosensory Transient Receptor Potential Ion Channels and Asthma
Biomedicines, 2021 Asthma is a widespread chronic disease of the bronchopulmonary system with a heterogeneous course due to the complex etiopathogenesis. Natural-climatic and anthropogenic factors play an important role in the development and progression of this pathology.
Oxana Yu. Kytikova +5 more
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Transient receptor potential channel polymorphisms are associated with the somatosensory function in neuropathic pain patients. [PDF]
PLoS ONE, 2011 Transient receptor potential channels are important mediators of thermal and mechanical stimuli and play an important role in neuropathic pain. The contribution of hereditary variants in the genes of transient receptor potential channels to neuropathic ...
Andreas Binder +21 more
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Transient Receptor Potential Channels and Auditory Functions. [PDF]
Antioxid Redox Signal, 2022 Significance: Transient receptor potential (TRP) channels are cation-gated channels that serve as detectors of various sensory modalities, such as pain, heat, cold, and taste. These channels are expressed in the inner ear, suggesting that they could also contribute to the perception of sound.
Ramkumar V +5 more
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