Results 111 to 120 of about 11,254,715 (215)
Targeting Transient Receptor Potential (TRP) Channels, Mas-Related G-Protein-Coupled Receptors (Mrgprs), and Protease-Activated Receptors (PARs) to Relieve Itch. [PDF]
Pharmaceuticals (Basel), 2023 Tsagareli MG +3 more
europepmc +1 more source
Research Progress on Upper Airway Cough Syndrome
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley +1 more source
Modulation of transient receptor potential (TRP) channels by plant derived substances used in over-the-counter cough and cold remedies. [PDF]
Respir Res, 2023 Stinson RJ, Morice AH, Sadofsky LR.
europepmc +1 more source
Where Eastern Medicine Meets Western Medicine: A World Review of the Management of Chronic Cough
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Purpose To summarize current Western and Eastern approaches to the evaluation and management of chronic cough, with particular emphasis on etiology‐directed therapy, cough hypersensitivity, behavioral interventions, neuromodulators, procedural treatments, and traditional remedies.
Thomas Zheng Jie Teng +5 more
wiley +1 more source
Geographical Variation in Thermal Adaptation of the Asiatic Toad (Bufo gargarizans)
Integrative Zoology, EarlyView.Northern and southern populations of Bufo gargarizans exhibit coordinated divergence in thermal preference, resting metabolic rate, and TRPM4 temperature sensitivity along a climatic gradient. ABSTRACT Thermal adaptation in animals can manifest in multiple dimensions, yet few studies have integrated behavioral, physiological, and molecular perspectives
Longcheng Fan, Yonghua Wu
wiley +1 more source
Transient Receptor Potential Channels and Calcium Signaling
, 2019 Transient receptor potential (TRP) cation channels play diverse roles in cellular Ca2+ signaling. First, as Ca2+-permeable channels that respond to a variety of stimuli, TRP channels can directly initiate cellular Ca2+ signals.
Vangeel, Laura, Voets, Thomas
core +1 more source
Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper
Allergy, EarlyView.ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg +18 more
wiley +1 more source
, 2012 Aims: Microdomain signalling mechanisms underlie key aspects of artery function and the modulation of intracellular calcium, with transient receptor potential (TRP) channels playing an integral role. This study determines the distribution and role of TRP
Sianne Toemoe (20029977) +14 more
core
Brain Pathology, EarlyView.Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen +8 more
wiley +1 more source
, 2007 Pulmonary and systemic arterial hypertension are associated with profound alterations in Ca2+ homeostasis and smooth muscle cell proliferation. A novel class of non-selective cation channels, the transient receptor potential (TRP) channels, have emerged ...
Yuan, Jason X.-J. +2 more
core +1 more source