Results 141 to 150 of about 19,126 (203)

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

Animal Research and One Health, Volume 4, Issue 3, Page 261-277, August 2026.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao, Jie Liu, Rui Yang, Xizhen Fan, Cheng Liang, Xin'e Shi, Jianjun Jin   +6 more
wiley   +1 more source

Correction: Transient Receptor Potential (TRP) Channels in Cochlear Function: Looking Beyond Mechanotransduction. [PDF]

J Assoc Res Otolaryngol
Nguyen T, Bergles DE.
europepmc   +1 more source

Comparative Neuroanatomy of Hydrothermal Vent Shrimps: Ecological Differentiation Among Four Alvinocaridid Species

Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.
Hydrothermal vent shrimps share a conserved brain architecture with enlarged mushroom bodies and terminal medullae, shaped by similar environmental pressures. Despite this similarity, some anatomical features near the brain vary between species, suggesting that some ecological factors, such as microhabitat and trophic strategies, also influence nervous
Adrien Mathou, Julia Machon, Rebecca Meth, Magali Zbinden, Juliette Ravaux, Steffen Harzsch   +5 more
wiley   +1 more source

Transient Receptor Potential (TRP) Channels in Cochlear Function: Looking Beyond Mechanotransduction. [PDF]

J Assoc Res Otolaryngol
Nguyen T, Bergles DE.
europepmc   +1 more source

Heart‐Specific Spinal and Vagal Afferents: Transcriptomic Signatures and Optogenetically Modulated Functional Coupling With Cardiomyocytes

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Selective purification of heart‐specific spinal and vagal sensory neurons by retrograde labeling and FACS purification showed enhanced spontaneous, optogenetic, and chemically stimulated Ca2+ activity. Transcriptomic profiling identified distinct ion channel and GPCR signatures in heart‐specific sensory neurons.
T. Akgul Caglar, Y. E. Kazci, Z. B. Durdu, S. Sahoglu Goktas, S. Bay, E. Vatandaslar, M. U. Turhan, G. Ozturk, E. Cagavi   +8 more
wiley   +1 more source

Role of thermosensitive transient receptor potential (TRP) channels in thermal preference of male and female mice. [PDF]

J Therm Biol
Carstens MI, Mahroke A, Selescu T, Carstens E.   +3 more
europepmc   +1 more source

Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3+/D120N mouse model of Lennox–Gastaut syndrome

Epilepsia Open, Volume 11, Issue 4, Page 1263-1275, August 2026.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and ...
Thomas Harman, Laura A. Sharman, Ka Lai Yip, Miguel Bedoya‐Pérez, Vaishali Janve, Jonathon C. Arnold   +5 more
wiley   +1 more source

Pharmacological or genetic targeting of Transient Receptor Potential (TRP) channels can disrupt the planarian escape response. [PDF]

PLoS One, 2019
Sabry Z, Ho A, Ireland D, Rabeler C, Cochet-Escartin O, Collins ES.   +5 more
europepmc   +1 more source

Evolutionarily conserved hydrophobicity and sterics in TM3/TM4 balance Orai1 pore opening

Protein Science, Volume 35, Issue 8, August 2026.
Abstract The calcium (Ca2+) channel Orai1—the pore‐forming subunit of the Ca2+ release‐activated Ca2+ channel—is opened by its physiological activator, the endoplasmic reticulum (ER)‐resident Ca2+ sensor stromal interaction molecule 1 (STIM1) upon ER Ca2+ store‐depletion.
Maximilian Fröhlich, Tamara Radišković, Valentina Hopl, Magdalena Prantl, Hadil Najjar, Selina Harant, Diana Thallinger, Muhammad Shehzad Anwar, Ferdinand Horvath, Julia Söllner, Yuliia Nazarenko, Matthias Sallinger, Nora Müller, Adéla Tiffner, Sarah Weiß, Herwig Grabmayr, Heinrich Krobath, Isabella Derler   +17 more
wiley   +1 more source

Non‐Contact Transspatial Regulatory Function of the Extracellular Matrix

Smart Medicine, Volume 5, Issue 4, August 2026.
Non‐contact transspatial regulation of the extracellular matrix (ECM), whereby the ECM remotely modulates cellular behavior without direct physical contact, is proposed and systematically investigated for the first time. This process involves multiple pathways and components, with actin‐dependent macropinocytosis playing a predominant role potentially.
Ting Cao, Chen Yang, Zhengyang Wang, Changmin Shao, Ziye Xu, Baode Chen, Jiayu Zhang, Yongcheng Wang, Fangfu Ye   +8 more
wiley   +1 more source