Results 211 to 220 of about 23,801 (234)
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Transient receptor potential vanilloid type 1 channels contribute to reflex cutaneous vasodilation in humans

Journal of Applied Physiology, 2012
Mechanisms underlying the cutaneous vasodilation in response to an increase in core temperature remain unresolved. The purpose of this study was to determine a potential contribution of transient receptor potential vanilloid type 1 (TRPV-1) channels to reflex cutaneous vasodilation.
Brett J, Wong, Sarah M, Fieger
openaire   +2 more sources

Roles of Transient Receptor Potential Vanilloid Subtype 1 and Cannabinoid Type 1 Receptors in the Brain: Neuroprotection versus Neurotoxicity

Molecular Neurobiology, 2007
Transient receptor potential vanilloid subtype 1 (TRPV1), also known as vanilloid receptor 1 (VR1), is a nonselective cation channel that is activated by a variety of ligands, such as exogenous capsaicin (CAP) or endogenous anandamide (AEA), as well as products of lipoxygenases.
Sang R, Kim   +7 more
openaire   +2 more sources

Cannabinoid type 1 receptors and transient receptor potential vanilloid type 1 channels in fear and anxiety—two sides of one coin?

Neuroscience, 2012
The transient receptor potential vanilloid type 1 channel (TRPV1; originally vanilloid receptor VR1) is activated in peripheral terminals of nociceptive fibers by noxious heat, low pH, and natural products such as capsaicin, the pungent ingredient of red-hot chilli peppers. Evidence has been accumulating that TRPV1 is expressed also in the brain, where
Moreira, F.   +4 more
openaire   +3 more sources

Essential role of transient receptor potential vanilloid type 1 in evodiamine‐mediated protection against atherosclerosis

Acta Physiologica, 2012
AbstractAimWe investigated whether transient receptor potential vanilloid type 1 (TRPV1) was involved in the therapeutic effect of evodiamine, a main bioactive component in the fruit of Evodiae rutaecarpa, on the development of atherosclerosis in apolipoprotein E‐deficient (ApoE−/−) mice and ApoE−/−TRPV1−/− mice.MethodsHistopathology was examined by ...
J, Wei   +6 more
openaire   +2 more sources

The role of transient receptor potential vanilloid type 1 in unimodal and multimodal object recognition task in rats

Pharmacological Reports, 2017
The role of transient receptor potential vanilloid type 1 (TRPV1) channels in learning and memory processes has recently been recognized. In the present study, the role of this receptor in the multisensory integration process was investigated.This study was done using 96 male Wistar rats, which were kept in a reverse 12-12h dark/light cycle.
Mahboobeh, Bannazadeh   +7 more
openaire   +2 more sources

A Polyclonal Antibody to the Prepore Loop of Transient Receptor Potential Vanilloid Type 1 Blocks Channel Activation

The Journal of Pharmacology and Experimental Therapeutics, 2006
Transient receptor potential vanilloid type 1 (TRPV1) can be activated by multiple chemical and physical stimuli such as capsaicin, anandamide, protons, and heat. Capsaicin interacts with the binding pocket constituted by transmembrane regions 3 and 4, whereas protons act through residues in the prepore loop of TRPV1.
Lana, Klionsky   +9 more
openaire   +2 more sources

The Transient Receptor Potential Vanilloid Type 1 Ion Channel in Hypometabolic Response to Hypoxia

Inquiry@Queen's Undergraduate Research Conference Proceedings, 2018
When challenged with low levels of available oxygen (hypoxia), larger mammals, including humans, attempt to maintain a consistent oxygen supply by increasing their rate of respiration. Smaller rodents and newborn mammals, on the other hand, respond to hypoxia by curtailing oxygen consumption.
openaire   +1 more source

XEN-D0501, a Novel Transient Receptor Potential Vanilloid 1 Antagonist, Does Not Reduce Cough in Patients with Refractory Cough

American Journal of Respiratory and Critical Care Medicine, 2017
Maria G Belvisi   +2 more
exaly  

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